Results 81 to 90 of about 24,815 (217)
BMC Biotechnology, 2012 Background Today, thrombosis is one of the most widely occurring diseases in modern life. Drugs with thrombolytic functions are the most effective methods in the treatment of thrombosis.
Yuan Jun +5 more
doaj +1 more source
The never ending success story of tranexamic acid in acquired bleeding
Haematologica, 2020 Tranexamic acid (TXA) is an anti-fibrinolytic agent that acts by inhibiting plasminogen activation and fibrinolysis. Although its first clinical use dates back more than 50 years, this hemostatic agent is still the object of intense clinical and ...
Massimo Franchini +1 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Triplet births, particularly those achieved by assisted reproductive technologies, entail markedly elevated maternal and fetal risks, including hypertensive diseases. Intracerebral hemorrhage is an uncommon but devastating complication during the postpartum period.
Raman Goit +8 more
wiley +1 more source
Use of intrapleural recombinant streptokinase in a pregnant woman with pleural empyema
Archivo Médico de Camagüey, 2018 Background: pneumonia complicates 0,78-2,7 per 1 000 pregnancies placing the mother and the fetus at risk. Empyema as a complication of pneumonia in a pregnant patient adds a high rate of morbidity and mortality to the mother and the fetus if one does ...
Miguel Emilio García Rodríguez +5 more
doaj
Bleeding related to disturbed fibrinolysis [PDF]
, 2016 The components and reactions of the fibrinolysis system are well understood. The pathway has fewer reactants and interactions than coagulation, but the generation of a complete quantitative model is complicated by the need to work at the solid‐liquid ...
Cawthern K.M. +12 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Immunoglobulin replacement therapy (IRT) for primary immunodeficiency reduces infection risk and subsequent complications and can be lifesaving. However, IRT can cause severe systemic adverse events (AEs) that may limit adequate dosing. These AEs may be caused, in part, by activation and/or consumption of complement proteins, thereby lowering ...
Douglas H. Jones, Heidi Memmott
wiley +1 more source
Фармация и фармакология (Пятигорск), 2019 The search and development of direct and rapid anticoagulants used per os, is an urgent problem in physiological and medical science. A number of plants contain heparin-like components with a positive effect on the hemostatic system, both within normal ...
M. G. Lyapina +3 more
doaj +1 more source
Reduction of Steroid-Induced Intraocular Pressure Elevation in Sheep by Tissue Plasminogen Activator [PDF]
, 2013 PURPOSE. To investigate whether tissue plasminogen activator (tPA) can prevent and/or reverse steroid-induced IOP elevation in an ovine model. METHODS.
Alvarez, Larry +5 more
core +2 more sources
Effects of immune checkpoint inhibitors on the pulmonary circulation in lung cancer patients
International Journal of Cancer, Volume 158, Issue 3, Page 682-696, 1 February 2026.What's new? Immune checkpoint inhibitors (ICIs) are effective against various cancers, but as more patients receive these therapies, more immune‐related adverse events (irAEs) emerge. Recent studies have suggested that ICIs are associated with an increase in pulmonary artery diameter and the ratio between pulmonary artery diameter and aortic diameter ...
Yao Xu +11 more
wiley +1 more source
Asn12 and Asn278: Critical Residues for In Vitro Biological Activity of Reteplase
Advances in Hematology, 2010 Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome.
Naganath Mandi +4 more
doaj +1 more source