Results 81 to 90 of about 3,220,825 (277)

Screening, production and biochemical characterization of a new fibrinolytic enzyme produced by Streptomyces sp. (Streptomycetaceae) isolated from Amazonian lichens [PDF]

open access: yes, 2016
Thrombosis is a pathophysiological disorder caused by accumulation of fibrin in the blood. Fibrinolytic proteases with potent thrombolytic activity have been produced by diverse microbial sources.
Afifah D.N.   +40 more
core   +2 more sources

Coagulopathy as a Complication of Cardiopulmonary Arrest Following Balloon Valvuloplasty in a Dog

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
An 8‐month‐old dog developed a consumptive coagulopathy and presumptive DIC following cardiac arrest during a balloon valvuloplasty procedure. Successful management required massive transfusion therapy and critical care. ABSTRACT Objective To describe successful management of a coagulopathy secondary to cardiopulmonary arrest (CPA) associated with ...
Marissa A. Turner, Theresa C. Hallowell
wiley   +1 more source

Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk [PDF]

open access: yes, 2017
An enhanced thrombotic environment and premature atherosclerosis are key factors for the increased cardiovascular risk in diabetes. The occlusive vascular thrombus, formed secondary to interactions between platelets and coagulation proteins, is composed ...
A Agren   +191 more
core   +2 more sources

Comparison of the Effectiveness of Nigella Sativa and Vitamin E in Preventing Intra‐abdominal Adhesions

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
In a rat model of intra‐abdominal adhesions, Vitamin E (vit E) and Nigella sativa (NS) oil were compared for their therapeutic effects. While both reduced inflammation and fibrosis, vit E demonstrated superior efficacy, significantly lowering TNF‐α levels, reducing fibrosis, and enhancing collagen maturation.
Musa Ozekinci   +3 more
wiley   +1 more source

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

open access: yesBioengineering & Translational Medicine, 2023
Postsurgical adhesions are a common complication of surgical procedures that can lead to postoperative pain, bowel obstruction, infertility, as well as complications with future procedures. Several agents have been developed to prevent adhesion formation,
Jiahui Chen   +7 more
doaj   +1 more source

Recent advances in cardiovascular medicines : thrombolytics [PDF]

open access: yes, 1990
Thrombolytic therapy represents a major advance in reducing mortality following myocardial infarction. Pharmacists must be aware of the principles and problems of thrombolysis and the extant large studies conducted in hospitals and in the community. This
Felice, Herbert   +2 more
core  

Production and characterization of new fibrinolytic protease from Mucor subtillissimus UCP 1262 in solid-state fermentation [PDF]

open access: yes, 2015
Fibrinolytic enzymes have received attention regarding their medicinal potential for thrombolytic diseases, a leading cause of morbidity and mortality worldwide.
Brandão, Romero Marcos Pedrosa   +7 more
core   +1 more source

Uptake of orally administered tranexamic acid in women during active labor: A pilot intervention study on prophylactic treatment of postpartum hemorrhage

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 7, Page 1347-1356, July 2025.
Women in active labor given oral tranexamic acid do reach therapeutic plasma concentrations. Time to therapeutic concentration is longer compared with intravenous administration, but duration in the therapeutic interval is significantly longer. Abstract Introduction Postpartum hemorrhage is the leading cause of maternal mortality worldwide.
Gita Strindfors   +2 more
wiley   +1 more source

Effect of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study). [PDF]

open access: yes, 2011
OBJECTIVE: To assess the effect of tranexamic acid (which reduces bleeding in surgical patients and reduces mortality due to bleeding in trauma patients) on intracranial haemorrhage in patients with traumatic brain injury.
CRASH-2 Collaborators, Intracranial Bleeding Study
core   +1 more source

Clot formation and resolution properties of platelets during cold storage for 21 days

open access: yesTransfusion, Volume 65, Issue 7, Page 1307-1318, July 2025.
Abstract Background Cold storage (2–6°C) preserves the aggregatory and clot formation properties of platelets beyond the standard 7‐day shelf life. Comparatively little is known about the effect of cold storage on clot resolution functions, which are necessary to ensure normal hemostatic balance is maintained.
Janhavi Mahajan   +3 more
wiley   +1 more source

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