Results 81 to 90 of about 34,989 (222)

Cancer‐Associated Fibroblasts: Origin, Classification, Tumorigenicity, and Targeting for Cancer Therapy

MedComm, Volume 6, Issue 11, November 2025.
This review explores the multifaceted roles of cancer‐associated fibroblasts (CAFs) in tumor biology. It examines their diverse origins, dynamic activation via signaling pathways, and spatial–temporal heterogeneity, proposing an updated classification of eight distinct CAF subtypes. The review highlights CAFs' contributions to tumor growth, metastasis,
Chang Fan, Wenlong Zhu, Yuan Chen, Wanwan Zhu, Jin Ding   +4 more
wiley   +1 more source

The Evolution of Functional Amyloids and Their Impact on Host–Microbe Interactions

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review describes functional amyloids and highlights the importance of structural repetition and molecular mimicry that distinguish the amyloid fold. The authors describe how amyloid can be the last universal common ancestor of protein folds. The authors also discuss how microbes utilize functional amyloids and how the structural characteristics of
Divya Kolli, Saroj K. Rout, Roland Riek, Matthew R. Chapman   +3 more
wiley   +1 more source

Current concepts of the management of dental extractions for patients taking warfarin [PDF]

, 2003
The document attached has been archived with permission from the Australian Dental Association. An external link to the publisher’s copy is included.Background: Controversy has surrounded the correct management of patients therapeutically anticoagulated ...
Akbarian M., Albrechtsen OK, Askey JM, Behrmann SJ, Birn H., Bjoerlin G., Bjorlen G., Carter G., Carter GD, Carter GD, Cosgriff SW., Davis B., Davis FB, Declerk D., Duperon DF, Duvoison GE, Frank BW, Gersel-Pedersen N., Gonias SL, Greenberg MS, Heine RD., Hidaka N., Hirsh J., Kovacs B., Kwapsis B., Lytle BW, Marshall J., Marshall V., Matras H., Moody GH., Mulligan R., Okamoto S., Quick AJ., Ramstrom G., Rijken DC, Roller L., Shira RB, Sindet-Pedersen S., Sindet-Pedersen S., Sindet-Pedersen S., Tulloch J., Vinkier F., Walsh PN., Wepner F., Ziffer AM, Zusman S.   +45 more
core   +1 more source

Technical Note and Short Review: A Challenging Case of a Premature Newborn Presenting With ICH, IVH, Ventriculitis, and Hydrocephalus

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Premature infants are at a heightened risk of intracerebral or intraventricular hemorrhages (IVH), which often lead to posthaemorrhagic hydrocephalus and necessitate the placement of a ventriculoperitoneal (VP) shunt. Here, we present a case involving suspected ICH, which led to multiloculated hydrocephalus, recurrent ventriculitis, and ...
Hannes Egermann, Christian Knorr, Basheer Al‐Shameri, Adolf Müller, Markus Denzinger, Stephan Lackermair   +5 more
wiley   +1 more source

Mutant and chimeric recobinant plasminogen activatorsproduction in eukaryotic cellsand preliminary characterization [PDF]

, 1987
Mutant urokinase-type plasminogen activator (u-PA) genes and hybrid genes between tissue-type plasminogen activator (t-PA) and u-PA have been designed to direct the synthesis of new plasminogen activators and to investigate the structure-function ...
Andre, B., Bollen, A., Collen, D., Cravador, A., Deforesta, F., Dewilde, M., Gheysen, D., Herzog, A., Hoylaerts, M., Jacobs, P., Pierard, L., Topisirovic, L.   +11 more
core   +1 more source

Characterization and In Vitro Probiotic Assessment of Alkalihalobacillus wakoensis as New Potent Probiotic Candidate

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Alkalihalobacillus wakoensis ATCC 21832 demonstrated excellent acid (95.6% survival at pH 2.5) and bile tolerance, produced catalase, protease, and nattokinase, and exhibited broad antimicrobial activity. The strain was sensitive to several antibiotics, formed moderate biofilm, showed high hydrophobicity, adhered to epithelial cells, and enhanced HepG ...
Ali Zarei, Ahmad Gholami, Zahra Kanannejad, Aydin Berenjian, Seyed Hesamodin Nabavizadeh, Milad Mohkam   +5 more
wiley   +1 more source

Non-Surgical Bleeding and Transurethral Resection of the Prostate (TURP) Syndrome after TURP Surgery: A Case Report and Literature Review

Pathophysiology
Patients undergoing transurethral resection of the prostate (TURP) surgery can develop TURP syndrome and post-TURP bleeding. Post-TURP bleeding can be surgical, from arteries or venous sinuses, or non-surgical, due to coagulopathy preventing clot ...
Akram M. Eraky, Sidney C. Rubenstein, Adnan Khan, Yasser Mokhtar, Nicole M. Gregorich   +4 more
doaj   +1 more source

Identification of Human Blood on the Basis of the Fibrin Plate Method [PDF]

, 1962
The method of identifying human blood is studied from the standpoint of the fibrinolytic enzyme system by means of the "fibrin plate method" and the following results are obtained: 1) "Fibrin plate method" is, in the point of its ...
Kumano, Osamu
core   +1 more source

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Ammollo, Aziz, Borissoff, Brill, Brinkmann, Clark, Esmon, Esmon, Fuchs, Fuchs, Gladysheva, Gleber, Guthold, Komissarov, Komorowicz, Longstaff, Longstaff, Massberg, Nikolova, Rocha, Ruf, Ryan, Rábai, Rácz, Saha, Sands, Scrutton, Semeraro, Silva, Smeeth, Walker, Weisel, Weisel, Wohner, Xu, Yang, Yeromonahos   +36 more
core   +1 more source

The two therapeutic strategies of surgical intervention and medical management in a patient with enhanced-fibrinolytic type of disseminated intravascular coagulation after aortic replacement for Stanford type A aortic dissection with chronic heart and renal failure

BMC Cardiovascular Disorders
Background Management of the enhanced-fibrinolytic type of disseminated intravascular coagulation (DIC) caused by aortic disorders is the two strategies of surgical intervention and medical treatment based on the patient’s age and comorbidities.
Hiroki Okamoto, Tomoya Ozawa, Tomoaki Suzuki, Yoshihisa Nakagawa   +3 more
doaj   +1 more source