Results 101 to 110 of about 34,662 (239)

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 928-941, April 2026.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Identification of Human Blood on the Basis of the Fibrin Plate Method [PDF]

open access: yes, 1962
The method of identifying human blood is studied from the standpoint of the fibrinolytic enzyme system by means of the "fibrin plate method" and the following results are obtained: 1) "Fibrin plate method" is, in the point of its ...
Kumano, Osamu
core   +1 more source

Intrapleural Gentian Violet Irrigation for Refractory Methicillin‐Resistant Staphylococcus aureus Empyema: A Case Series

open access: yesRespirology Case Reports, Volume 14, Issue 4, April 2026.
This case series demonstrates that intrapleural gentian violet (GV) irrigation is a safe and effective adjunct for refractory MRSA empyema. GV irrigation achieved rapid bacterial clearance (median 5 days) without procedural complications or systemic toxicity, providing a viable alternative when standard surgical debridement and systemic antibiotics ...
Yasoo Sugiura   +7 more
wiley   +1 more source

A Parallel Group, 1:1 Randomised, Pilot Study Comparing the Clinical Efficacy and Bleeding Risk Between Low Dose and Standard Dose Intrapleural Tissue Plasminogen Activator for Adults With Pleural Infection

open access: yesRespirology Case Reports, Volume 14, Issue 4, April 2026.
This protocol is for the TRAPPE study, a pilot study to serve as preparatory work before proceeding to a full‐scale, multicentre RCT. The feasibility of the study design involving flexibility of dose escalation and various clinical parameters will be tested for suitability as study outcome measurements before proceeding to a full‐scale RCT.
Ken Ka Pang Chan   +4 more
wiley   +1 more source

Hemostatic disturbances in acute ischemic stroke [PDF]

open access: yes, 2012
Background: Stroke is the 2nd most common cause of death after ischemic heart disease. About 85% of all strokes are caused by a thrombus or an embolus in the cerebral circulation.
Rooth, Elisabeth
core   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

open access: yesInternational Endodontic Journal, Volume 59, Issue 4, Page 590-613, April 2026.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer   +2 more
wiley   +1 more source

Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha

open access: yesBMC Biotechnology, 2012
Background Currently, the two most commonly used fibrinolytic agents in thrombolytic therapy are recombinant tissue plasminogen activator (rt-PA) and streptokinase (SK).
Moussa Manal   +7 more
doaj   +1 more source

Use of intrapleural recombinant streptokinase in a pregnant woman with pleural empyema

open access: yesArchivo Médico de Camagüey, 2018
Background: pneumonia complicates 0,78-2,7 per 1 000 pregnancies placing the mother and the fetus at risk. Empyema as a complication of pneumonia in a pregnant patient adds a high rate of morbidity and mortality to the mother and the fetus if one does ...
Miguel Emilio García Rodríguez   +5 more
doaj  

A method to quantitatively characterize the formation and dissociation of tumor cell clusters using light transmission aggregometry

open access: yesMolecular Oncology
In this paper, we have modified the workflow of the traditional light transmission aggregometry (LTA) protocol to characterize tumor cell clusters in vitro in a quantifiable and multifaceted manner.
Regina Komal Kottana   +2 more
doaj   +1 more source

The Recent History of Platelets in Thrombosis and Other Disorders [PDF]

open access: yes, 2005
The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 25 November 2003. Introduction by Professor Tom Meade, London School of Hygiene and Tropical Medicine.First published by the Wellcome ...
Reynolds, LA, Tansey, EM
core  

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