Purification of fibrinolytic enzyme from Bacillus amyloliquefaciens GUTU06 and properties of the enzyme [PDF]
Food Chemistry: X, 2023 A producing-fibrinolytic enzyme strain was isolated with high yield. The strain was identified as Bacillus amyloliquefaciens. B. amyloliquefaciens GUTU06 fibrinolytic enzyme was purified by acetone precipitation and reverse micelle. Acetone precipitation
Jialin Wu +6 more
semanticscholar +4 more sources
A Novel Bi-Functional Fibrinolytic Enzyme with Anticoagulant and Thrombolytic Activities from a Marine-Derived Fungus Aspergillus versicolor ZLH-1 [PDF]
Marine Drugs, 2022 Fibrinolytic enzymes are important components in the treatment of thrombosis-associated disorders. A new bi-functional fibrinolytic enzyme, versiase, was identified from a marine-derived fungus Aspergillus versicolor ZLH-1.
Lihong Zhao +5 more
semanticscholar +4 more sources
Purification and Characterization of a Fibrinolytic Enzyme from Marine Bacillus velezensis Z01 and Assessment of Its Therapeutic Efficacy In Vivo [PDF]
Microorganisms, 2022 Fibrinolytic enzymes are the most effective agents for the treatment of thrombotic diseases. In the present study, we purified and characterized an extracellular fibrinolytic serine metalloprotease (named Velefibrinase) that is produced by marine ...
Yuting Zhou +4 more
semanticscholar +4 more sources
Non-sterile Submerged Fermentation of Fibrinolytic Enzyme by Marine Bacillus subtilis Harboring Antibacterial Activity With Starvation Strategy [PDF]
Frontiers in Microbiology, 2019 Microbial fibrinolytic enzyme is a promising candidate for thrombolytic therapy. Non-sterile production of fibrinolytic enzyme by marine Bacillus subtilis D21-8 under submerged fermentation was realized at a mild temperature of 34°C, using a unique ...
Shihan Pan +4 more
semanticscholar +4 more sources
Enhanced Production of Fibrinolytic Enzyme from Pseudomonas aeruginosa by Optimization Media Components [PDF]
Journal of Applied Sciences and Nanotechnology, 2021 *Corresponding Author: Bilal H. Jasim as.18.18@grad.uotechnology.edu.iq Abstract Fibrinolytic enzyme is factor that lysis fibrin clots. This fibrinolytic factor has prospective use to treat cardiovascular diseases, such as stroke and heart attack ...
B. Jasim, E. Ali
semanticscholar +2 more sources
Fibrin and Fibrinolytic Enzyme Cascade in Thrombosis: Unravelling the Role [PDF]
Life (Basel), 2023 Blood clot formation in blood vessels (thrombosis) is a major cause of life-threatening cardiovascular diseases. These clots are formed by αA-, βB-, and ϒ-peptide chains of fibrinogen joined together by isopeptide bonds with the help of blood coagulation
Rajni Singh +3 more
semanticscholar +2 more sources
Increase of a Fibrinolytic Enzyme Production through Promoter Replacement of aprE3-5 from Bacillus subtilis CH3-5 [PDF]
J Microbiol Biotechnol, 2021 Bacillus subtilis CH3-5 isolated from cheonggukjang secretes a 28 kDa protease with a strong fibrinolytic activity. Its gene, aprE3-5, was cloned and expressed in a heterologous host (Jeong et al., 2007).
Z. Yao +6 more
semanticscholar +2 more sources
Fibrinolytic Enzyme from Green Microalgae: A New Potential Drug for Thrombolytic Therapy?
Phycology, 2023 Thrombosis is characterized by the pathological formation of fibrin clots within a blood vessel, leading to the obstruction of blood flow. Fibrinolytic enzymes from microorganisms have been shown to be more efficient and safer in dissolving clots.
Yanara Alessandra Santana Moura +5 more
semanticscholar +3 more sources
Fermentation, 2023 Fibrinolytic enzymes are a kind of proteolytic enzymes that can hydrolyze fibrin and dissolve blood clots. They could be used as a therapeutic agent for treating thrombosis.
Zixuan He +8 more
semanticscholar +3 more sources
Isolation, Extraction, Purification, and Characterization of Fibrinolytic Enzyme from Pseudomonas aeruginosa and Estimation of the Molecular Weight of the Enzyme [PDF]
Archives of Razi Institute, 2021 Pseudomonas aeruginosa was isolated from injuries of patients' wounds and burns, and to ensure that the isolate was belonging to P. aeruginosa, several tests were performed, such as staining techniques, a biochemical test, morphological test, Vitek 2 ...
B. H Jasim, E. H Ali
doaj +2 more sources