Results 41 to 50 of about 889,079 (196)

All tangled up: interactions of the fibrinolytic and innate immune systems

Frontiers in Medicine, 2023
The hemostatic and innate immune system are intertwined processes. Inflammation within the vasculature promotes thrombus development, whilst fibrin forms part of the innate immune response to trap invading pathogens.
Claire S. Whyte
doaj   +1 more source

Heterologous Expression of the Fibrinolytic Enzyme Gene from Bacillus velezensis 20-1, Isolated from Sojae Semen Praeparatum and Application of Recombinant Strain Containing It in the Production of Sojae Semen Praeparatum [PDF]

Shipin Kexue
In this study, 65 strains of dominant bacteria were isolated from Sojae Semen Praeparatum (SSP) from different regions and screened for their fibrinolytic enzyme activity by enzyme-linked immunosorbent assay (ELISA). Bacillus velezensis 20-1 was selected
XU Jingwen, WU Rina, WANG Weiming, YAN Yiran, XIANG Xueqin, ZHAO Yulian, WU Junrui, WANG Yaqi, DENG Li, TONG Xing, SHI Haisu
doaj   +1 more source

Immobilization of fibrinolytic enzyme

Blood & Vessel, 1978
Today, many investigators have made their efforts to retard or prevent the thrombogenesis on the surface of material which was intended for prolonged intravascular inplantation and developed some polymers which were covered with silicon, low energy, negative charge, hydrogel, anticoagulant substance etc.Then, we also have considered to devise the ...
Takeshi OHSHIRO, Akio SUGITACHI, Seong Deoh HONG, Kiyoshi MUKAI, Fumio MURAKAMI, Goro KOSAKI, Shigemi MOTOI   +6 more
openaire   +3 more sources

Optimization of Physical and Cultural Conditions of Fibrinolytic Enzyme from Bacillus altitudinis S-CSR 0020

Journal of Pure and Applied Microbiology, 2018
The main aim of this work was optimization of physical conditions as well as medium components for the maximum production of fibrinolytic enzyme. A fibrinolytic enzyme producing organism was isolated from soil and identified as Bacillus altitudinis ...
K.V. Smitha, B.V. Pradeep
doaj   +1 more source

Therapeutic and Anti-Thrombotic Properties of Some Naturally Fermented Soybean Foods of the Eastern Himalayas

Fermentation, 2023
Naturally fermented soybean foods have anti-thrombotic properties due to the presence of microbial fibrinolytic enzymes. However, fibrinolytic enzyme-producing bacteria from naturally fermented soybean foods of the Eastern Himalayas viz.
Pynhunlang Kharnaior, Mayouri Das, Jyoti Prakash Tamang   +2 more
doaj   +1 more source

Production and biochemical and biophysical characterization of fibrinolytic protease of a Mucor subtilissimus strain isolated from the caatinga biome [PDF]

Anais da Academia Brasileira de Ciências
Cardiovascular diseases, resulting from the deposition of clots in blood vessels, are the leading cause of death worldwide. Fibrinolytic enzymatic activity can catalyze blood clot degradation. Findings show that 36 fungal isolates recovered from Caatinga
AMANDA EMMANUELLE S. CONNIFF, THIAGO P. NASCIMENTO, ROMERO MARCOS P.B. COSTA, LEONID BREYDO, CAMILA S. PORTO, ATTILIO CONVERTI, JOYCE G.W. SIQUEIRA, JOSE ANTONIO TEIXEIRA, GALBA MARIA DE CAMPOS-TAKAKI, VLADIMIR N. UVERSKY, ANA LÚCIA F. PORTO, TATIANA S. PORTO   +11 more
doaj   +1 more source

FIBRINOLYTIC ENZYME FROM BACILLUS AMYLOLIQUEFACIENS: OPTIMISATION AND SCALE UP STUDIES [PDF]

, 2014
Objective: This research work was carried out to identify a potent microorganism, which produced the fibrinolytic enzyme and to optimise the media and growth parameters to achieve the maximal enzyme production for commercial application.
Gad, Rajani Gopal, Nirmala, S., Sivvaswamy, S. Narendar   +2 more
core   +1 more source

The effect of age on the fibrinolytic enzyme system [PDF]

Journal of Clinical Pathology, 1974
Components of the fibrinolytic enzyme system, FR-antigen and fibrinogen, were measured in 20 healthy volunteers aged 20-40 years and in 61 elderly subjects aged 66-96 years. Plasminogen activator levels did not significantly differ between the 20-40 and 66-75 age groups, but were higher in those over 75.
P J, Hamilton, A A, Dawson, D, Ogston, A S, Douglas   +3 more
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source