Results 51 to 60 of about 889,079 (196)

Purification and Properties of a Plasmin-like Marine Protease from Clamworm (Perinereis aibuhitensis)

Marine Drugs
Marine organisms are a rich source of enzymes that exhibit excellent biological activity and a wide range of applications. However, there has been limited research on the proteases found in marine mudflat organisms.
Tingting Jiang, Bing Zhang, Haixing Zhang, Mingjun Wei, Yue Su, Tuo Song, Shijia Ye, Yuping Zhu, Wenhui Wu   +8 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

SCREENING AND BIOSYTNTHESIS OF FIBRINOLYTIC ENZYME FROM ASPERGILLUS JAPONICUM [PDF]

, 2015
Fibrin is a protein that forms in the blood clots after trauma or injury. This is essential to stop blood loss. There are more than twenty enzymes in the body that assist in clotting of the blood, while only one that can break the clot down.
Siddalingeshwara, K G, Yadav, Saroj
core   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Nattokinase: A hope in cardiovascular therapy and more [PDF]

Romanian Journal of Medical Practice, 2020
Nattokinase is a fibrinolytic enzyme identified and isolated in 1987 from a specific Japanese food called natto (a kind of vegetable cheese). Since its discovery and until now, nattokinase has been studied experimentally and clinically almost exclusively
Dan-Dominic IONESCU
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Isolation of thermotolerant bacteria producing fibrinolytic enzyme [PDF]

, 2015
Fibrinolytic enzymes were widely used in the treatment of cardiovascular diseases. However, the efficiency of the commercial enzymes are still lack of perfection because there are many side effects as well as not tolerant to downstream processing such as
Mohamad Ezreen Haikal bin Mahat
core   +1 more source

Pharmacological pain relief and postpartum bleeding in women with moderate or severe anemia: A cohort analysis of the WOMAN‐2 trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Pain relief could minimize blood loss by limiting the adrenaline stress response to fear and trauma during birth. We examined the association between pharmacological pain relief and postpartum bleeding in a large cohort of women giving birth with anemia in sub‐Saharan Africa and South Asia.
Judith Lieber, Monica Arribas, Maha Asad, Eni Balogun, Folasade Adenike Bello, Amy Brenner, Rizwana Chaudhri, Amber Geer, Kiran Javaid, Aasia Kayani, Katharine Ker, Mwansa Ketty Lubeya, Raoul Mansukhani, Projestine Muganyizi, Oladapo Olayemi, Danielle Prowse, Ian Roberts, Haleema Shakur‐Still, Bellington Vwalika, The WOMAN‐2 Trial Collaborators, France Donnay, Racheal Phiri, Tina Lavender, Ghazala Mahmud, Jens Kieckbusch, James Lawrence, Sari Watson, Jane Armitage, Maria Quigley, Olufemi T. Oladapo, Sabaratnam Arulkumaran, Imelda Bates, Bukola Fawole, Danielle Prowse, Danielle Beaumont, Charlotte Fleming, Collette Barrow, Llion Roberts, Julio Gil Onandia, Madeleine Cargill, Andrew Thayne, Christiana Alao, Petula Buck, Raoul Mansukhani, Tim Collier, Mbwana Mohammed, Myriam Benyahia, Projestine Muganyizi, Alice Kawala, Rose Temba, Oladapo Olayemi, Olujide Okunade, Bellington Vwalika, Aziz‐un‐Nisa Abbasi, Ruqqia Sultana, Shehla Noor, Ansa Islam, Sadia Bibi, Sundus Khan, Wajeeha Khurshid, Shahida Magsi, Basma Zia, Haleema Yasmin, Khadija Bano, Saba Khan, Naheed Fatima, Bushra Sher Zaman, Sohail Mahmood Chaudhry, Shakila Yasmin, Khiaynat Sarwar Hashmi, Nadia Babar, Arif Tajammul, Alia Bashir, Farah Siddique, Fouzia Perveen, Nusrat Shah Kamal, Riffat Jaleel, Sarah Kazi, Aruna Hira, Pushpa Makhija, Syeda Batool Mazhar, Nasira Tasnim, Saera Afghan, Mussarat Batool, Sobia Luqman, Fouzia Kashif, Shaista Hifaz Abro, Javeria Abro, Najma Ghaffar, Rakhshanda Mushtaq, Safia Bibi, Shamsa Humayun, Zohra Khanum, Noreen Akmal, Shamila Ijaz Munir, Aisha Malik, Amna Zia Eusaph, Sofia Manzoor, Khola Yousaf, Misbah Kausar, Yasmeen Waqas, Naila Ehsan, Aisha Siddiqa, Uzma Suhail Afridi, Nosheen Sikandar, Rehana Kamaal, Mehnaz Khakwani, Rashida Perveen, Huma Quddusi, Hajira Masood, Syeda Ali, Asma Akhter, Mubashra Samina, Sana Ishfaque, Humaira Bilqis, Shahid Irshad Rao, Saima Ashraf, Uzma Shaheen, Tayyiba Wasim, Natasha Rasool, Nabeela Waheed, Khansa Iqbal, Shahida Husain Tarar, Rizwana Khalid, Rubina Sohail, Shehla Kanwal, Shagufta Saeed Sial, Humera Noreen, Naila Israr, Shehla Baqai, Asifa Siraj, Luzango Maembe, Julius Nyambarino, Enid Simon Chiwanga, Lazaro Y. Madeha, Francis Ngimwichi Joseph, Evelyne Ludovick, Baya H Kissiwa, Sangalala Mtingele, Vincent Tarimo, Alfred Secha, Hudson August Manyanga, Idrisa Hussein, Alphonce Moyo, Delila Msigwa, France John Rwegoshora, Delfina Mkenda, Mojisola Mobolaji‐Ojibara, Michael Babalola, Owa Olorunfemi Oludele, Samuel Ojo, Oladipo Aremu, Kehinde Ogundairo, Oyewole Tunde Aremu, Gazaal Rasheedat, Iman Usman, Auwal Shuaibu, Adewale Adeyemi, Olufemi Aworinde, Theresa Irinyenikan, Mwansa Ketty Lubeya, Kenneth Chanda   +161 more
wiley   +1 more source

Production, purification and characterization of novel fibrinolytic enzyme from Bacillus atrophaeus V4

, 2023
© 2022, The Author(s), under exclusive licence to Plant Science and Biodiversity Centre, Slovak Academy of Sciences (SAS), Institute of Zoology, Slovak Academy of Sciences (SAS), Institute of Molecular Biology, Slovak Academy of Sciences (SAS).This study
ADIGÜZEL, Ahmet, Demir, Yeliz, TAŞKIN, Mesut, ALBAYRAK, Şeyda, Varol, Ayse, ÖZKAN, Hakan   +5 more
core   +1 more source