Cytocompatibility and cell proliferation evaluation of calcium phosphate-based root canal sealers [PDF]
Restorative Dentistry & Endodontics, 2020 ObjectivesThis study aimed to evaluate the cell viability and migration of Endosequence Bioceramic Root Canal Sealer (BC Sealer) compared to MTA Fillapex and AH Plus.Materials and MethodsBC Sealer, MTA Fillapex, and AH Plus were placed in contact with ...
Letícia Boldrin Mestieri +5 more
doaj +1 more source
Indonesian Journal of Biotechnology, 2022 Full‐thickness wound healing is a complex process requiring a well‐orchestrated mechanism of various factors, including cytokines, particularly interleukin (IL)‐10 and transforming growth factor (TGF)‐β.
Adi Muradi Muhar +6 more
doaj +1 more source
In vitro assessment of Neuronal PAS domain 2 mitigating compounds for scarless wound healing
Frontiers in Medicine, 2023 BackgroundThe core circadian gene Neuronal PAS domain 2 (NPAS2) is expressed in dermal fibroblasts and has been shown to play a critical role in regulating collagen synthesis during wound healing.
Adam Clements +7 more
doaj +1 more source
The Effect Of Arbutin On The Expression Of Tumor Suppressor P53, BAX/BCL-2 Ratio And Oxidative Stress Induced By Tert-Butyl Hydroperoxide In Fibroblast And LNcap Cell Lines [PDF]
Cell Journal, 2021 Objective: Arbutin (p-hydroxyphenyl-β-D-glucopyranoside) possesses beneficial functions including antioxidant, antiinflammatory, and anti-tumoral activities.
Shima Ebadollahi +4 more
doaj +1 more source
A Fibroblast Is Not a Fibroblast Is Not a Fibroblast [PDF]
Journal of Investigative Dermatology, 2018 Fibrosis after injury is a huge public health concern, leading to morbidity, mortality, and expenditure of billions of health care dollars. Recent mouse studies have shown that dermal fibroblasts are heterogeneous. New research using single-cell RNA sequencing to identify major fibroblast populations in humans is paving the way to a better ...
Michael S, Hu +2 more
openaire +2 more sources
Therapeutic Potential of Adipose Stem Cell-Derived Conditioned Medium on Scar Contraction Model
Biomedicines, 2022 Scars are composed of stiff collagen fibers, which contract strongly owing to the action of myofibroblasts. To explore the substances that modulate scar contracture, the fibroblast-populated collagen lattice (FPCL) model has been used.
Yukiko Imai +10 more
doaj +1 more source
Cosmetics, 2022 The macroscopic and microscopic deterioration of human skin with age is, in part, attributed to a functional decline in mitochondrial health. We previously demonstrated that exercise attenuated age-associated changes within the skin through enhanced ...
Irena Alexandra Rebalka +3 more
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Fibroblasts – the cellular choreographers of wound healing
Frontiers in Immunology, 2023 Injuries to our skin trigger a cascade of spatially- and temporally-synchronized healing processes. During such endogenous wound repair, the role of fibroblasts is multifaceted, ranging from the activation and recruitment of innate immune cells through ...
Samuel Knoedler +14 more
doaj +1 more source
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD71+ and CD235a+ erythroid like progenitor [PDF]
BioImpactsIntroduction: Ex vivo blood production is an urgent need of most countries, and creating production protocols can save the lives of many patients. Despite the recent advances in blood production in ex vivo conditions, its high-scale production is not yet
Nafiseh Karoubi +4 more
doaj +1 more source
Arterial wall fibrosis in Takayasu arteritis and its potential for therapeutic modulation
Frontiers in Immunology, 2023 Arterial wall damage in Takayasu arteritis (TAK) can progress despite immunosuppressive therapy. Vascular fibrosis is more prominent in TAK than in giant cell arteritis (GCA).
Durga Prasanna Misra +3 more
doaj +1 more source