Results 11 to 20 of about 510,893 (315)
AGE AND MULTIPLICATION OF FIBROBLASTS [PDF]
Journal of Experimental Medicine, 1921 Pure cultures of fibroblasts displayed marked differences in their activity in the plasma of young, middle aged, and old chickens. The rate of cell multiplication varied in inverse ratio to the age of the animal from which the plasma was taken. There was a definite relation between the age of the animal and the amount of new tissue produced in its ...
Alexis Carrel, Albert H. Ebeling
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A Fibroblast Is Not a Fibroblast Is Not a Fibroblast [PDF]
Journal of Investigative Dermatology, 2018 Fibrosis after injury is a huge public health concern, leading to morbidity, mortality, and expenditure of billions of health care dollars. Recent mouse studies have shown that dermal fibroblasts are heterogeneous. New research using single-cell RNA sequencing to identify major fibroblast populations in humans is paving the way to a better ...
Michael S. Hu +2 more
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Therapeutic downregulation of neuronal PAS domain 2 (Npas2) promotes surgical skin wound healing
eLife, 2022 Attempts to minimize scarring remain among the most difficult challenges facing surgeons, despite the use of optimal wound closure techniques. Previously, we reported improved healing of dermal excisional wounds in circadian clock neuronal PAS domain 2 ...
Yoichiro Shibuya +11 more
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Frontiers in Medicine, 2020 Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited therapeutic options. The current model suggests that chronic or repetitive “micro-injuries” of the alveolar epithelium lead to activation and proliferation of ...
Julia Nemeth +2 more
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Pifu-xingbing zhenliaoxue zazhi, 2021 Objective: To investigate the role of LncRNAs that regulate cathepsin D in chronic light-damaged skin cells and explore their role in the mechanism of skin photoaging. Methods: Cultured human dermal fibroblasts were induced to a photoaging cells model by
Weichun XU +3 more
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eLife, 2021 A monolayer of highly motile cells can establish long-range orientational order, which can be explained by hydrodynamic theory of active gels and fluids.
Tianfa Xie +5 more
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Dental Journal, 2016 Background: Wound healing is a biological process associated with tissue growth and regeneration. Wound healing process, is important to repair damaged tissue.
Gunawan Oentaryo +2 more
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Single-cell RNA sequencing reveals distinct immunology profiles in human keloid
Frontiers in Immunology, 2022 Keloids, characterized by skin fibrosis and excessive accumulation of extracellular matrix, remain a therapeutic challenge. In this study, we systematically capture the cellular composition of keloids by the single-cell RNA sequencing technique.
Cheng Feng +16 more
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Frontiers in Pharmacology, 2022 Background: Vincristine (VCR) is used in the clinic as an anti-tumor drug. VCR can cause pulmonary fibrosis (PF), leading to respiratory failure. The transformation of fibroblasts into myofibroblasts may play a key role in PF. The present study attempted
Hui Xu +11 more
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Frontiers in Immunology, 2023 IntroductionHigh stress in the compartment surrounded by the deep fascia can cause acute compartment syndrome (ACS) that may result in necrosis of the limbs.
Tao Wang +24 more
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