Results 301 to 310 of about 1,957,077 (351)
Cadherin-11 integrates Piezo1 and interleukin-6 signaling to promote fibroblast activation.
Astrab LR, Caliari SR.
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Fibroblast Activation in Scleroderma
Scandinavian Journal of Rheumatology, 1984Skin fibroblast cultures started from 6 scleroderma patients and 5 controls were compared with respect to synthesis of collagen and glycosaminoglycans. Fibroblast strains started from skin biopsy material from patients with active localized disease exhibited appreciably increased synthesis of collagen, whereas cultures from old sclerodermatous areas ...
T K, Vuorio +3 more
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Journal of Molecular and Cellular Cardiology, 2015
Fibroblast activation protein α (FAP) is a membrane-bound serine protease expressed by activated fibroblasts during wound healing in the skin. Expression of FAP after myocardial infarction (MI) and potential effects on cardiac wound healing are largely unknown.MI was induced in rats and FAP expression was analyzed at 3, 7 and 28 days post-MI by ...
Paolo Galuppo +2 more
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Fibroblast activation protein α (FAP) is a membrane-bound serine protease expressed by activated fibroblasts during wound healing in the skin. Expression of FAP after myocardial infarction (MI) and potential effects on cardiac wound healing are largely unknown.MI was induced in rats and FAP expression was analyzed at 3, 7 and 28 days post-MI by ...
Paolo Galuppo +2 more
exaly +3 more sources
Oral Diseases, 2023
Abstract Objectives Fibroblast activating protein (FAP) is associated with various organ fibrosis. However, the expression and molecular function of FAP in oral submucous fibrosis (OSF) is still unclear. Materials and Methods
Ming Li +6 more
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Abstract Objectives Fibroblast activating protein (FAP) is associated with various organ fibrosis. However, the expression and molecular function of FAP in oral submucous fibrosis (OSF) is still unclear. Materials and Methods
Ming Li +6 more
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Activation of fibroblasts in cancer stroma
Experimental Cell Research, 2010Tumor microenvironment has emerged as an important target for cancer therapy. In particular, cancer-associated fibroblasts (CAF) seem to regulate many aspects of tumorigenesis. CAFs secrete a variety of soluble factors that act in a paracrine manner and thus affect not only cancer cells, but also other cell types present in the tumor stroma.
Kati, Räsänen, Antti, Vaheri
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Activated fibroblasts in cancer: Perspectives and challenges
Cancer Cell, 2023Activated fibroblasts in tumors, or cancer-associated fibroblasts (CAFs), have become a popular research area over the past decade. As important players in many aspects of tumor biology, with functions ranging from collagen deposition to immunosuppression, CAFs have been the target of clinical and pre-clinical studies that have revealed their potential
Giuseppina, Caligiuri, David A, Tuveson
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Activation of fibroblast proliferation by Werner's syndrome fibroblast-conditioned medium
Journal of Dermatological Science, 1994The effects of Werner's syndrome (WS) fibroblast-conditioned medium on cell proliferation and collagen production of normal fibroblasts were studied using four WS fibroblast strains. The conditioned medium from the WS fibroblasts brought about activation of normal fibroblast proliferation, whereas, that from late passage normal fibroblasts and ...
A, Hatamochi +3 more
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Ecto-protein kinase activity of fibroblasts
Archives of Biochemistry and Biophysics, 1979Abstract Isolated, intact dermal fibroblasts can transfer the terminal phosphate of adenosine triphosphate, [γ- 32 P]ATP, to an exogenously added macromolecule (histone). The incorporation of labeled phosphate to histone is attributed to an extracellularly directed protein kinase activity (ecto-kinase) which cannot be accounted for by soluble ...
T M, Chiang, E S, Kang, A H, Kang
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Hypotensive Activity of Fibroblast Growth Factor
Science, 1991Acidic and basic fibroblast growth factors (FGFs) are members of a family of proteins that are broad-spectrum mitogens, have diverse hormone-like activities, and function in tumorigenesis. FGF's ability to raise the concentration of intracellular calcium ion suggests that FGF could induce the synthesis of endothelium-derived relaxing factor (EDRF) and ...
P, Cuevas +5 more
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