Results 291 to 300 of about 1,957,077 (351)

Diosmetin Modulates EMT-Associated Plasticity and Fibroblast-Activation Markers in Parallel Breast Cancer In Vitro Models. [PDF]

Molecules
Michalczyk M, Kubik J, Józefczyk A, Iwan M, Humeniuk E, Adamczuk G, Michalczuk M, Madej-Czerwonka B, Czerwonka M, Korga-Plewko A.   +9 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Bazedoxifene Targets gp130 Signaling to Suppress Fibroblast Activation in Pathological Cutaneous Fibrosis: Insights from Spatial Transcriptomics and scRNA-seq Data. [PDF]

Int J Biol Sci
Wang Z, Zhang H, Tu L, He J, Wang R, Su Y, Tang S, Li Q, Xia W, Gao Y, Zhao Y, Huang X, Zan T.   +12 more
europepmc   +1 more source

ECM-Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling. [PDF]

Adv Sci (Weinh)
Packirisamy S, André O, Fan Z, Nordenfelt P, Swaminathan VS.   +4 more
europepmc   +1 more source

Fibroblast Activation Protein Inhibitor (FAPI) PET: A Scoping Review of Emerging Oncologic and Fibroinflammatory Applications. [PDF]

Diagnostics (Basel)
Panagiotidis E, Koinis F, Zhang-Yin J, Angelidis G, Valotassiou V, Tsougos I, Kotsakis A, Georgoulias P.   +7 more
europepmc   +1 more source

Inhibition of fibroblast activation protein partially restores the homeostatic phenotype of mechanoactivated synoviocytes. [PDF]

Osteoarthritis Cartilage
Bernstein ER, Stoeckl BD, Flaugh R, Laforest L, Burt KG, Dyment NA, Scanzello CR, Mauck RL, Miller L.   +8 more
europepmc   +1 more source

Single-cell transcriptomics landscape decodes cardiac fibroblast heterogeneity and reveals PDK4-driven profibrotic activation during cardiac fibrosis

Xiaohui Qi, Suxiang Guo, Yujin Sun, Luzheng Zhang, Kongli Lu, Xi Huang, Ri Tang, Ning Zhang, Dingyi Yu, Lian Feng   +9 more
openalex   +1 more source

Linezolid-mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition. [PDF]

Arthritis Rheumatol
Hong X, Xiao Y, Qi H, Zhu S, Filla T, Györfi AH, Li YN, Xu M, Zhi L, Trinh-Minh T, Dees C, Schett G, Distler JHW, Matei AE.   +13 more
europepmc   +1 more source

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger K. Rosdahl, Brendan Gilmore, Oliver Seifert   +3 more
openalex   +1 more source