Results 201 to 210 of about 320,743 (259)

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

Insulin-like growth factor-2 mRNA-binding protein 2 facilitates post-ischemic angiogenesis by increasing the stability of fibroblast growth factor 2 mRNA and its protein expression. [PDF]

Heliyon
Ma S, Hu Y, Xu W, Xiong W, Xu X, Hou Y, Wang Y, Chen P, Yang W, Lu H, Zhao Y.   +10 more
europepmc   +1 more source

Autonomous Navigation of Pollen‐Inspired Magnetic Microrobots for Biomedical Applications

Advanced Robotics Research, EarlyView.
A sunflower pollen‐inspired magnetic microrobot enables controlled rolling navigation in vessel‐like environments. Its open geometry reduces hydrodynamic drag, while vision‐based closed‐loop control, shortest‐path planning, and reinforcement learning support target‐reaching and maze navigation with microrobot‐scale accuracy, highlighting a route toward
Ali Anil Demircali, Abdurrahim Yilmaz, Meysam Keshavarz, Jinshi Zhao, Ara Darzi, Eric Yeatman, Burak Temelkuran   +6 more
wiley   +1 more source

Fibroblast Growth Factor 2 (FGF2) Activates Vascular Endothelial Growth Factor (VEGF) Signaling in Gastrointestinal Stromal Tumors (GIST): An Autocrine Mechanism Contributing to Imatinib Mesylate (IM) Resistance. [PDF]

Cancers (Basel)
Boichuk S, Dunaev P, Galembikova A, Valeeva E.   +3 more
europepmc   +1 more source

Wireless Precise Manipulation of Tumor Spheroids Using a Millirobot Controlled by Permanent Magnetic Traps

Advanced Robotics Research, EarlyView.
A magnetic donut‐like millirobot is developed for label‐free pick‐and‐place of a tumor spheroid wirelessly controlled by a magnetic trap. Spheroids are important 3D multicellular culture systems that recapitulate key structural and functional features of native tissues.
Yue Gao, Moonkwang Jeong, Anni G. Muñoz, Ann‐Sophia Müller, Fangchao Long, Shengqiang Zhou, Juntian Qu, Leoni A. Kunz‐Schughart, Tian Qiu   +8 more
wiley   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Potential of Titanium Pins Coated with Fibroblast Growth Factor-2-Calcium Phosphate Composite Layers to Reduce the Risk of Impaired Bone-Pin Interface Strength in the External Fixation of Distal Radius Fractures. [PDF]

J Clin Med
Mutsuzaki H, Yanagisawa Y, Noguchi H, Ito A, Yamazaki M.   +4 more
europepmc   +1 more source

All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model. [PDF]

Iran J Basic Med Sci
Rustamzadeh A, Anjomshoa M, Bahreini N, Darabi S, Rezaie MJ, Rezaei S, Rahimi-Madiseh M, Deris F, Zamani S.   +8 more
europepmc   +1 more source

High molecular weight heparin-induced angiogenesis mainly mediated via basic fibroblast growth factor-2- an in-vivo (CAM) and in-silico analysis. [PDF]

Biochem Biophys Rep
Manjunathan R, Mitra K, Vasvani R, Doble M.   +3 more
europepmc   +1 more source