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Upstream Regulators of Fibroblast Growth Factor 23

Frontiers in Endocrinology, 2021
Fibroblast growth factor 23 (FGF23) has been described as an important regulator of mineral homeostasis, but has lately also been linked to iron deficiency, inflammation, and erythropoiesis. FGF23 is essential for the maintenance of phosphate homeostasis
Danielle M. A. Ratsma, M. Carola Zillikens, Bram C. J. van der Eerden   +2 more
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Fibroblast growth factors [PDF]

Current Biology, 2003
What are they? Fibroblast growth factors (FGFs) are a family of small (20–30kDa) intercellular signalling proteins which are frequently found to be glycosylated. The first draft of the human genome identified 29 potential FGF genes, and so far transcripts have been identified for 23 of them.
openaire   +3 more sources

Computer-assisted stabilization of fibroblast growth factor FGF-18

Computational and Structural Biotechnology Journal, 2023
The fibroblast growth factors (FGF) family holds significant potential for addressing chronic diseases. Specifically, recombinant FGF18 shows promise in treating osteoarthritis by stimulating cartilage formation.
Jan Vilim, Tereza Ghazalova, Eliska Petulova, Aneta Horackova, Veronika Stepankova, Radka Chaloupkova, David Bednar, Jiri Damborsky, Zbynek Prokop   +8 more
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Fibroblast growth factor receptors in breast cancer

Tumor Biology, 2017
Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their roles in embryogenesis, tissue homeostasis, and development of breast cancer.
Shuwei Wang, Zhongyang Ding
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Fibroblast growth factor 19 stimulates water intake

Molecular Metabolism, 2022
Fibroblast growth factor 19 (FGF19) is a hormone with pleiotropic metabolic functions, leading to ongoing development of analogues for treatment of metabolic disorders. On the other hand, FGF19 is overexpressed in a sub-group of hepatocellular carcinoma (
José Ursic-Bedoya, Carine Chavey, Guillaume Desandré, Lucy Meunier, Anne-Marie Dupuy, Iria Gonzalez-Dopeso Reyes, Thierry Tordjmann, Eric Assénat, Urszula Hibner, Damien Gregoire   +9 more
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Functional interaction of fibroblast growth factor 8b and androgen in prostate cancer cell proliferation

Tumor Biology, 2017
Fibroblast growth factor 8b and androgen play important roles in cell proliferation of prostate cancer. We investigated the effects of fibroblast growth factor 8b and androgen on the proliferation of prostate cell lines and the corresponding ...
Wen-jun Xiao, Gui-ming Zhang, Ding-wei Ye   +2 more
doaj   +1 more source

Comparative genomic analysis of eutherian fibroblast growth factor genes

BMC Genomics, 2020
Background The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either ...
Marko Premzl
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Fibroblast growth factor 21 and bone homeostasis

Biomedical Journal, 2023
Fibroblast growth factor 21 (FGF21), a member of the FGF subfamily, is produced primarily in the liver and adipose tissue. The main function of FGF21 is to regulate energy metabolism of carbohydrates and lipids in the body through endocrine and other ...
Yan Tang, Mei Zhang
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Fibroblast growth factor 21 in metabolic syndrome

Frontiers in Endocrinology, 2023
Metabolic syndrome is a complex metabolic disorder that often clinically manifests as obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension.
Ming Yang, Ming Yang, Chongbin Liu, Chongbin Liu, Na Jiang, Na Jiang, Yan Liu, Yan Liu, Shilu Luo, Shilu Luo, Chenrui Li, Chenrui Li, Hao Zhao, Hao Zhao, Yachun Han, Yachun Han, Wei Chen, Wei Chen, Li Li, Li Li, Li Xiao, Li Xiao, Lin Sun, Lin Sun   +23 more
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In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

Journal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts, Brooke L Farrugia, Rylie A Green, Jelena Rnjak-Kovacina, Penny J Martens   +4 more
doaj   +1 more source