Results 1 to 10 of about 350,938 (306)

Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy

Drug Design, Development and Therapy, 2016
Anna Szlachcic, Malgorzata Zakrzewska, Michal Lobocki, Piotr Jakimowicz, Jacek Otlewski Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland Abstract: Fibroblast growth factor receptors (FGFRs) are ...
Szlachcic A, Zakrzewska M, Lobocki M, Jakimowicz P, Otlewski J   +4 more
doaj   +1 more source

Distinct effects of Fgf7 and Fgf10 on the terminal differentiation of murine bladder urothelium revealed using an organoid culture system

BMC Urology, 2023
Background Dysregulation of the terminal differentiation of bladder urothelium is associated with the pathogenesis of urinary tract disorders. Fibroblast growth factor (Fgf)7 and Fgf10 stimulate urothelial proliferation; however, their roles in cellular ...
Kazuto Suda, Yuka Matsumoto, Takanori Ochi, Hiroyuki Koga, Nobutaka Hattori, Atsuyuki Yamataka, Tetsuya Nakamura   +6 more
doaj   +1 more source

Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes

Open Access Rheumatology: Research and Reviews, 2009
Hee-Jeong Im,1–4 Andrew D Sharrocks,5 Xia Lin,6 Dongyao Yan,1 Jaesung Kim,1 Andre J van Wijnen,7 Robert A Hipskind81Departments of Biochemistry, 2Internal Medicine, 3Section of Rheumatology, Orthopedic Surgery, 4Rush University Medical Center ...
Hee-Jeong Im, Andrew D Sharrocks, Xia Lin, et al   +3 more
doaj  

Fibroblast Growth Factor 6

Differentiation
Fibroblast Growth Factor 6 (FGF6), also referred to as HST2 or HBGF6, is a member of the Fibroblast Growth Factor (FGF), the Heparin Binding Growth Factor (HBGF) and the Heparin Binding Secretory Transforming Gene (HST) families. The genomic and protein structure of FGF6 is highly conserved among varied species, as is its expression in muscle and ...
Jennelle Smith, Loydie A. Jerome-Majewska   +1 more
openaire   +2 more sources

Association between fibroblast growth factor 23 and functional capacity among independent elderly individuals

Einstein (São Paulo)
Objective To examine the association of between serum fibroblast growth factor 23 and the functional capacity among independent individuals, aged 80 or older.
Lara Miguel Quirino Araújo, Patrícia Ferreira do Prado Moreira, Clineu de Mello Almada Filho, Luciano Vieira de Araújo, Aline Granja Costa, Ricardo de Castro Cintra Sesso, John P Bilezikian, Marise Lazaretti-Castro, Maysa Seabra Cendoroglo   +8 more
doaj   +2 more sources

Physiological Actions of Fibroblast Growth Factor-23

Frontiers in Endocrinology, 2018
Fibroblast growth factor-23 (FGF23) is a bone-derived hormone suppressing phosphate reabsorption and vitamin D hormone synthesis in the kidney. At physiological concentrations of the hormone, the endocrine actions of FGF23 in the kidney are αKlotho ...
Reinhold G. Erben
doaj   +1 more source

Mutations in fibroblast growth factor (FGF8) and FGF10 identified in patients with conotruncal defects

Journal of Translational Medicine, 2020
Background Conotruncal defects (CTDs) are a type of heterogeneous congenital heart diseases (CHDs), but little is known about their etiology. Increasing evidence has demonstrated that fibroblast growth factor (FGF) 8 and FGF10 may be involved in the ...
Kun Sun, Shuang Zhou, Qingjie Wang, Zhuo Meng, Jiayu Peng, Yue Zhou, Wenting Song, Jian Wang, Sun Chen   +8 more
doaj   +1 more source

Il Fibroblast Growth Factor-23 (FGF-23)

Giornale di Clinica Nefrologia e Dialisi, 2018
Negli ultimi due decenni, l'identificazione delle proprietà biologiche del Fibroblast Growth Factor 23 (FGF23) ha notevolmente ampliato le conoscenze sulla regolazione endocrina e paracrina dell'omeostasi dei fosfati e sulle relazioni intercorrenti tra ...
D. Rendina, G. De Filippo, R. Muscariello, F. De Pascale, P. Strazzullo   +4 more
doaj   +1 more source

Growth factors of fibroblasts and vascular en-dothelium in the early stages of knee osteoarthritis [PDF]

Саратовский научно-медицинский журнал, 2018
Aim: to compare and study the relationship between the maintenance of vascular endothelial growth factor and acidic fibroblast growth factor in individuals with the initial clinical and radiological manifestations of the degeneration of the hyaline ...
Puchinyan D.M., Gladkova E.V., Karyakina E.V., Romakina N.A., Belova S.V.   +4 more
doaj  

siRNA-mediated silencing of bFGF gene inhibits the proliferation, migration, and invasion of human pituitary adenoma cells

Tumor Biology, 2017
Human pituitary adenoma is one of the most common intracranial tumors with an incidence as high as 16.7%. Recent evidence has hinted a relationship between growth factors of pituitary or hypothalamic origin and proliferation of human pituitary adenoma ...
Kai Zhou, Yan-Dong Fan, Serick Duysenbi, Peng-Fei Wu, Zhao-Hai Feng, Zheng Qian, Ting-Rong Zhang   +6 more
doaj   +1 more source