Results 21 to 30 of about 527,016 (306)

Fibroblast growth factor 21 and bone homeostasis

Biomedical Journal, 2023
Fibroblast growth factor 21 (FGF21), a member of the FGF subfamily, is produced primarily in the liver and adipose tissue. The main function of FGF21 is to regulate energy metabolism of carbohydrates and lipids in the body through endocrine and other ...
Yan Tang, Mei Zhang
doaj   +1 more source

Master regulators of FGFR2 signalling and breast cancer risk. [PDF]

, 2013
The fibroblast growth factor receptor 2 (FGFR2) locus has been consistently identified as a breast cancer risk locus in independent genome-wide association studies. However, the molecular mechanisms underlying FGFR2-mediated risk are still unknown. Using
Caldas, Carlos, Castro, Mauro AA, Chin, Suet-Feung, de Santiago, Ines, Fletcher, Michael NC, Markowetz, Florian, Meyer, Kerstin B, O'Reilly, Martin, Ponder, Bruce AJ, Rueda, Oscar M, Wang, Xin   +10 more
core   +2 more sources

Functional interaction of fibroblast growth factor 8b and androgen in prostate cancer cell proliferation

Tumor Biology, 2017
Fibroblast growth factor 8b and androgen play important roles in cell proliferation of prostate cancer. We investigated the effects of fibroblast growth factor 8b and androgen on the proliferation of prostate cell lines and the corresponding ...
Wen-jun Xiao, Gui-ming Zhang, Ding-wei Ye   +2 more
doaj   +1 more source

Comparative genomic analysis of eutherian fibroblast growth factor genes

BMC Genomics, 2020
Background The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either ...
Marko Premzl
doaj   +1 more source

Fibroblast growth factor 21 in metabolic syndrome

Frontiers in Endocrinology, 2023
Metabolic syndrome is a complex metabolic disorder that often clinically manifests as obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension.
Ming Yang, Ming Yang, Chongbin Liu, Chongbin Liu, Na Jiang, Na Jiang, Yan Liu, Yan Liu, Shilu Luo, Shilu Luo, Chenrui Li, Chenrui Li, Hao Zhao, Hao Zhao, Yachun Han, Yachun Han, Wei Chen, Wei Chen, Li Li, Li Li, Li Xiao, Li Xiao, Lin Sun, Lin Sun   +23 more
doaj   +1 more source

Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]

, 2017
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo, Altissimi, Giancarlo, Artico, Marco, Bardella, Lia, Giangaspero, Felice, Minni, Antonio, Parnigotto, Pier Paolo, Pastore, Francesco Saverio, Spoletini, Marialuisa, Taurone, Samanta, Tombolini, Mario, Wierzbicki, Venceslao   +11 more
core   +1 more source

In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

Journal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts, Brooke L Farrugia, Rylie A Green, Jelena Rnjak-Kovacina, Penny J Martens   +4 more
doaj   +1 more source

The key components of Schwann cell-like differentiation medium and their effects on gene expression pattern of adipose-derived stem cells. [PDF]

, 2015
BackgroundSchwann cell-like cells differentiated from adipose-derived stem cells may have an important role in peripheral nerve regeneration. Herein, we document the individual effects of growth factors in Schwann cell-like differentiation medium ...
Lankford, Lee, Little, Christopher J, Olson, Christine A, Orbay, Hakan, Sahar, David E   +4 more
core   +1 more source

Analysis of the Effects of Five Factors Relevant to In Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput mRNA-Profiling [PDF]

, 2014
The in vitro process of chondrogenic differentiation of mesenchymal stem cells for tissue engineering has been shown to require three-dimensional culture along with the addition of differentiation factors to the culture medium.
Brinchmann, Jan E., Jakobsen, Rune B., Mikkelsen, Tarjei S., Zhang, Xiaolan, Østrup, Esben   +4 more
core   +11 more sources

Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis

Clinics, 2012
OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis.
Daniel Reis Waisberg, Edwin Roger Parra, João Valente Barbas-Filho, Sandra Fernezlian, Vera Luiza Capelozzi   +4 more
doaj   +1 more source