Results 21 to 30 of about 11,074,756 (345)

The Fibroblast Growth Factor signaling pathway

Wiley Interdisciplinary Reviews: Developmental Biology, 2015
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF receptors (FGFRs).
D. Ornitz, N. Itoh
semanticscholar   +1 more source

Presence and localization of a 30-kDa basic fibroblast growth factor-like protein in rodent testes [PDF]

, 1991
We have used a recently characterized rabbit antiserum against basic fibroblast growth factor (bFGF), which recognizes various forms of bFGF, to examine the presence and localization of bFGF in the testes of adult rats and mice and the 5-day-old rat.
Russell, J. T., Grothe, C., Gratzl, Manfred, Mayerhofer, Artur, Rudolf, M.   +4 more
core   +1 more source

Molecular networks in FGF signaling: Flotillin-1 and Cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2 [PDF]

, 2012
Fibroblast growth factor receptor substrate 2 (FRS2α) is a signaling adaptor protein that regulates downstream signaling of many receptor tyrosine kinases.
Traub Stephanie, Tomasovic, Ana, Stephanie Traub, Ana Tomasovic, Ana Tomasovic (189773), Ritva Tikkanen (189783), Tikkanen Ritva, Tikkanen, Ritva, Traub, Stephanie, Tomasovic Ana, Ritva Tikkanen, Stephanie Traub (189777)   +11 more
core   +2 more sources

Fibroblast-growth-factor-23 in heart failure with preserved ejection fraction: relation to exercise capacity and outcomes

, 2020
AimsThis study aimed to assess plasma fibroblast growth factor 23 (FGF23) in patients with heart failure with preserved ejection fraction (HFpEF) and its relation to inflammation, renal function, clinical and imaging characteristics, exercise capacity ...
JN Khan (7756580), P Kanagala (7717895), IB Squire (7717910), M Eltayeb (9441314), GP McCann (7687148), LL Ng (7717913), JR Arnold (7717907), P Gupta (7703555), A Singh (7717904), GS Gulsin (7708124)   +9 more
core   +3 more sources

Analysis of Drosophila Fibroblast Growth Factor Functional Domains [PDF]

, 2011
The exciting Fibroblast Growth Factor (FGF) field lies at the crossroads of cell signaling, development, evolution, trafficking, physiology and human disease.
Tulin, Sarah Lynn
core   +1 more source

Receptor Specificity of the Fibroblast Growth Factor Family*

Journal of Biological Chemistry, 1996
Fibroblast growth factors (FGFs) are essential molecules for mammalian development. The nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced variants) are expressed in specific spatial and temporal patterns.
D. Ornitz, Jing-Song Xu, Jennifer S. Colvin, Donald G. McEwen, C. A. Macarthur, F. Coulier, G. Gao, M. Goldfarb   +7 more
semanticscholar   +1 more source

Fibroblast Growth Factor 22 is not essential for skin development and repair but plays a role in tumorigenesis [PDF]

, 2012
Fibroblast Growth Factors play critical roles during development, tissue homeostasis and repair by controlling cell proliferation, survival, migration and differentiation.
Robbez-Masson, L, Ian Rosewell, Grose Richard, Cross, B, Rosewell, I, Athina-Myrto Chioni (156542), Robbez-Masson, Luisa, Rosewell Ian, Chioni Athina-Myrto, Jarosz, Monika, Barbara Cross (156544), Barbara Cross, Grose, Richard, Chioni, A-M, Rosewell, Ian, Cross Barbara, Richard Grose (156552), Chioni, Athina-Myrto, Cross, Barbara, Jarosz, M, Luisa Robbez-Masson (156539), Grose, R, Luisa Robbez-Masson, Jarosz Monika, Ian Rosewell (156548), Monika Jarosz, Richard Grose, Robbez-Masson Luisa, Monika Jarosz (156537), Athina-Myrto Chioni   +29 more
core   +2 more sources

Upstream Regulators of Fibroblast Growth Factor 23

Frontiers in Endocrinology, 2021
Fibroblast growth factor 23 (FGF23) has been described as an important regulator of mineral homeostasis, but has lately also been linked to iron deficiency, inflammation, and erythropoiesis. FGF23 is essential for the maintenance of phosphate homeostasis
Danielle M. A. Ratsma, M. Carola Zillikens, Bram C. J. van der Eerden   +2 more
doaj   +1 more source

Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors

Cells, 2019
Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases expressed on the cell membrane that play crucial roles in both developmental and adult cells.
S. Dai, Zhan Zhou, Zhu-Chu Chen, Guang-Yu Xu, Yongheng Chen   +4 more
semanticscholar   +1 more source

Fibroblast growth factor 19 stimulates water intake

Molecular Metabolism, 2022
Fibroblast growth factor 19 (FGF19) is a hormone with pleiotropic metabolic functions, leading to ongoing development of analogues for treatment of metabolic disorders. On the other hand, FGF19 is overexpressed in a sub-group of hepatocellular carcinoma (
José Ursic-Bedoya, Carine Chavey, Guillaume Desandré, Lucy Meunier, Anne-Marie Dupuy, Iria Gonzalez-Dopeso Reyes, Thierry Tordjmann, Eric Assénat, Urszula Hibner, Damien Gregoire   +9 more
doaj   +1 more source