Results 11 to 20 of about 352,093 (306)

Fibroblast growth factor 10 attenuates advanced liver fibrosis through hepatocyte fibroblast growth factor receptor 2 signalling [PDF]

open access: yesClinical and Translational Medicine
Background Metabolic dysfunction–associated steatotic liver disease (MASLD) and advanced fibrotic stages are significant contributors to cirrhosis and liver‐related mortality, yet no therapies directly target fibrosis in the later stages of the disease ...
Xuanxin Yang   +20 more
doaj   +2 more sources

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis [PDF]

open access: yesCytokine & Growth Factor Reviews, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans, and integrins.
PRESTA, Marco   +5 more
openaire   +4 more sources

Fibroblast growth factor receptors in breast cancer

open access: yesTumor Biology, 2017
Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their roles in embryogenesis, tissue homeostasis, and development of breast cancer.
Shuwei Wang, Zhongyang Ding
doaj   +2 more sources

Fibroblast growth factors as tissue repair and regeneration therapeutics [PDF]

open access: yesPeerJ, 2016
Cell communication is central to the integration of cell function required for the development and homeostasis of multicellular animals. Proteins are an important currency of cell communication, acting locally (auto-, juxta-, or paracrine) or ...
Quentin M. Nunes   +4 more
doaj   +3 more sources

Research progress of fibroblast growth factor homologous factor 1 in the pathogenesis of arrhythmia [PDF]

open access: yesJichu yixue yu linchuang, 2020
Fibroblast growth factor homologous factor 1 (FHF1) is an intracellular signaling protein, a non-specific fibroblast growth factor that does not bind to fibroblast growth factor receptors. FHF1 combines with the C-terminus of cardiac voltage-gated sodium
QIN Tao, LI Qing, LI Ju-xiang
doaj   +1 more source

RANTES and fibroblast growth factor 2 in jawbone cavitations: triggers for systemic disease?

open access: yesInternational Journal of General Medicine, 2013
Johann Lechner,1 Volker von Baehr2 1Clinic for Integrative Dentistry, Munich, Germany; 2Compartment of Immunology and Allergology on Institute for Medical Diagnostics in MVZ GbR, Berlin, Germany Background: Jawbone cavitations (JC) are hollow dead spaces
Lechner J, von Baehr V
doaj   +1 more source

Fibroblast growth factor signaling in macrophage polarization: impact on health and diseases

open access: yesFrontiers in Immunology
Fibroblast growth factors (FGFs) are a versatile family of peptide growth factors that are involved in various biological functions, including cell growth and differentiation, embryonic development, angiogenesis, and metabolism. Abnormal FGF/FGF receptor
Luyao Shen   +3 more
doaj   +3 more sources

Overexpression of fibroblast growth factor 13 ameliorates amyloid-β-induced neuronal damage

open access: yesNeural Regeneration Research, 2023
Previous studies have shown that fibroblast growth factor 13 is downregulated in the brain of both Alzheimer’s disease mouse models and patients, and that it plays a vital role in the learning and memory.
Ruo-Meng Li   +4 more
doaj   +1 more source

Conversion of a Paracrine Fibroblast Growth Factor into an Endocrine Fibroblast Growth Factor [PDF]

open access: yesJournal of Biological Chemistry, 2012
FGFs 19, 21, and 23 are hormones that regulate in a Klotho co-receptor-dependent fashion major metabolic processes such as glucose and lipid metabolism (FGF21) and phosphate and vitamin D homeostasis (FGF23). The role of heparan sulfate glycosaminoglycan in the formation of the cell surface signaling complex of endocrine FGFs has remained unclear. Here
Goetz R   +10 more
openaire   +2 more sources

Molecular description of fibroblast growth factor and mechanisms by which fibroblast growth factor-21 mediating biological actions and acting as a biologic biomarker of cardiovascular diseases

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2020
Fibroblast growth factor (FGF) family members are mostly secreted as signaling proteins with diverse functions in development and metabolism. FGFs can be classified as intracellular, paracrine, and endocrine FGFs by their action mechanisms.
Leta Shiferaw Melaku, Negeri Debela
doaj   +1 more source

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