Results 31 to 40 of about 11,074,756 (345)

Fibroblast growth factor 21 controls mitophagy and muscle mass

Journal of Cachexia, Sarcopenia and Muscle, 2019
Skeletal muscle is a plastic tissue that adapts to changes in exercise, nutrition, and stress by secreting myokines and myometabolites. These muscle‐secreted factors have autocrine, paracrine, and endocrine effects, contributing to whole body homeostasis.
Lynette J. Oost, M. Kustermann, A. Armani, B. Blaauw, V. Romanello   +4 more
semanticscholar   +1 more source

Functional interaction of fibroblast growth factor 8b and androgen in prostate cancer cell proliferation

Tumor Biology, 2017
Fibroblast growth factor 8b and androgen play important roles in cell proliferation of prostate cancer. We investigated the effects of fibroblast growth factor 8b and androgen on the proliferation of prostate cell lines and the corresponding ...
Wen-jun Xiao, Gui-ming Zhang, Ding-wei Ye   +2 more
doaj   +1 more source

Computer-assisted stabilization of fibroblast growth factor FGF-18

Computational and Structural Biotechnology Journal, 2023
The fibroblast growth factors (FGF) family holds significant potential for addressing chronic diseases. Specifically, recombinant FGF18 shows promise in treating osteoarthritis by stimulating cartilage formation.
Jan Vilim, Tereza Ghazalova, Eliska Petulova, Aneta Horackova, Veronika Stepankova, Radka Chaloupkova, David Bednar, Jiri Damborsky, Zbynek Prokop   +8 more
doaj   +1 more source

Comparative genomic analysis of eutherian fibroblast growth factor genes

BMC Genomics, 2020
Background The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either ...
Marko Premzl
doaj   +1 more source

Fibroblast growth factor 21 and bone homeostasis

Biomedical Journal, 2023
Fibroblast growth factor 21 (FGF21), a member of the FGF subfamily, is produced primarily in the liver and adipose tissue. The main function of FGF21 is to regulate energy metabolism of carbohydrates and lipids in the body through endocrine and other ...
Yan Tang, Mei Zhang
doaj   +1 more source

Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism [PDF]

, 2004
Defects of either anosmin-1 or fibroblast growth factor receptor 1 (FGFR1) are known to underlie hereditary Kallmann's syndrome (KS), a human disorder of olfactory and gonadotropin-releasing hormone (GnRH) neuronal ontogeny.
Guimond, S, Bouloux, PM, Turnbull, Jeremy, Turnbull, J, Hu, Youli, Kim, SH, Kim, Soo-Hyun, Schofield, Jonathan, Winyard, P, Winyard, Paul, Vannelli, GB, Bouloux, Pierre-Marc, Gonzalez-Martinez, D, Hu, YL, Schofield, J, Vannelli, Gabriella Barbara, González-Martínez, David, Guimond, Scott   +17 more
core   +1 more source

Fibroblast growth factor 21 in metabolic syndrome

Frontiers in Endocrinology, 2023
Metabolic syndrome is a complex metabolic disorder that often clinically manifests as obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension.
Ming Yang, Ming Yang, Chongbin Liu, Chongbin Liu, Na Jiang, Na Jiang, Yan Liu, Yan Liu, Shilu Luo, Shilu Luo, Chenrui Li, Chenrui Li, Hao Zhao, Hao Zhao, Yachun Han, Yachun Han, Wei Chen, Wei Chen, Li Li, Li Li, Li Xiao, Li Xiao, Lin Sun, Lin Sun   +23 more
doaj   +1 more source

In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

Journal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts, Brooke L Farrugia, Rylie A Green, Jelena Rnjak-Kovacina, Penny J Martens   +4 more
doaj   +1 more source

Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis

Annual review of nutrition, 2018
Fibroblast growth factor 21 (FGF21) is an endocrine hormone derived from the liver that exerts pleiotropic effects on the body to maintain overall metabolic homeostasis.
Lucas D. BonDurant, Matthew J. Potthoff
semanticscholar   +1 more source

Lower cerebrospinal fluid/plasma fibroblast growth factor 21 (FGF21) ratios and placental FGF21 production in gestational diabetes [PDF]

, 2013
Objectives: Circulating Fibroblast Growth Factor 21 (FGF21) levels are increased in insulin resistant states such as obesity, type 2 diabetes mellitus and gestational diabetes mellitus (GDM). In addition, GDM is associated with serious maternal and fetal
Muhammad F Bari, Bari Muhammad F., Sivakumar, Kavitha, Randeva Harpal S., Bari, Muhammad F., Tan, Bee K., Tan Bee K., Randeva, Harpal S., Harpal S Randeva, Bee K Tan, Sivakumar Kavitha, Vatish Manu, Kavitha Sivakumar, Vatish, Manu, Manu Vatish   +14 more
core   +2 more sources