Results 211 to 220 of about 320,743 (259)

Fibroblast growth factor-2

The International Journal of Biochemistry & Cell Biology, 2000
Fibroblast growth factor-2 (FGF-2) is a heparin-binding growth factor which occurs in several isoforms resulting from alternative initiations of translation: an 18 kD cytoplasmic isoform and four larger molecular weight nuclear isoforms (22, 22.5, 24 and 34 kD).
M, Okada-Ban, J P, Thiery, J, Jouanneau
openaire   +4 more sources

Fibroblast growth factor-2 and cardioprotection

Heart Failure Reviews, 2007
Boosting myocardial resistance to acute as well as chronic ischemic damage would ameliorate the detrimental effects of numerous cardiac pathologies and reduce the probability of transition to heart failure. Experimental cardiology has pointed to ischemic and pharmacological pre- as well as post-conditioning as potent acute cardioprotective ...
Elissavet, Kardami   +6 more
openaire   +2 more sources

FIBROBLAST GROWTH FACTOR 1 AND FIBROBLAST GROWTH FACTOR 2 IMMUNOREACTIVITY IN GASTROINTESTINAL TUMOURS

The Journal of Pathology, 1997
Acidic and basic fibroblast growth factors (FGF-1 and FGF-2) are mitogenic polypeptides that may play a role in autocrine and paracrine growth control of malignant tumours. We have examined the expression of FGF-1 and FGF-2 in a series of 41 colorectal tumours (24 adenomas, 17 adenocarcinomas) and 50 gastric adenocarcinomas (23 intestinal, 27 diffuse),
I, el-Hariry, M, Pignatelli, N, Lemoine
openaire   +2 more sources

A Glycopolymer Chaperone for Fibroblast Growth Factor-2

Bioconjugate Chemistry, 2004
Mono- and disaccharide-containing glycopolymers were synthesized by cyanoxyl-mediated polymerization of acrylamide with acrylate-derivatized mono- and disaccharides. We demonstrate that a glycopolymer bearing pendant, fully sulfated lactose units effectively replaces heparin and heparan sulfate as a molecular chaperone for fibroblast growth factor-2 ...
Ran, Guan   +4 more
openaire   +2 more sources

Immunohistochemical localization of growth factors fibroblast growth factor-1 and fibroblast growth factor-2 and receptors fibroblast growth factor receptor-2 and fibroblast growth factor receptor-3 in normal oral epithelium, epithelial dysplasias, and squamous cell carcinoma

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2002
Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been identified in a variety of carcinomas, but there are few studies concerning their presence in oral cancers. The objective of this study was to determine whether FGF-1, FGF-2, and high affinity receptors FGFR2 and FGFR3 are present in the pathogenesis of oral epithelial dysplasias ...
Candice, Wakulich   +3 more
openaire   +2 more sources

The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and its role in haematological malignancies

Cytokine & Growth Factor Reviews, 2007
Basic fibroblast growth factor/fibroblast growth factor-2 is one of the best characterized of the pro-angiogenic cytokines. This review describes its history, as well as its role in tumor angiogenesis associated with haematological malignancies, as traced by the main contributions to the international medical literature.
RIBATTI D   +3 more
openaire   +2 more sources

Expression of Fibroblast Growth Factor-1 and Fibroblast Growth Factor-2 in Normal Liver and Hepatocellular Carcinoma

Digestive Diseases and Sciences, 1998
This study was performed to examine the immunohistochemical expression of fibroblast growth factor-1 and fibroblast growth factor-2 in normal liver and a total of 31 cases of hepatocellular carcinoma (HCC). Reactivity for both types of angiogenic factor did not exist in any cellular component of normal liver.
N H, Chow   +6 more
openaire   +2 more sources

The role of fibroblast growth factor-2 (FGF-2) in hematopoiesis

Progress in Growth Factor Research, 1995
Basic fibroblast growth factor (bFGF or FGF-2) is an angiogenic and pleiotropic growth factor involved in the proliferation and differentiation of numerous cell types. It is expressed mostly in tissues of mesoderm and neuroectoderm origin, and is thought to play an important role in the mesoderm induction.
M, Allouche, A, Bikfalvi
openaire   +2 more sources

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