Results 41 to 50 of about 232,776 (304)
PKC regulates the production of fibroblast growth factor 23 (FGF23).
PLoS ONE, 2019 Serine/threonine protein kinase C (PKC) is activated by diacylglycerol that is released from membrane lipids by phospholipase C in response to activation of G protein-coupled receptors or receptor tyrosine kinases.
Ludmilla Bär +2 more
doaj +1 more source
Osteocytes and the pathogenesis of hypophosphatemic rickets
Frontiers in Endocrinology, 2022 Since phosphorus is a component of hydroxyapatite, its prolonged deprivation affects bone mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate homeostasis and is mainly produced by osteocytes.
Miwa Yamazaki, Toshimi Michigami
doaj +1 more source
Intravenous phosphate loading increases fibroblast growth factor 23 in uremic rats. [PDF]
PLoS ONE, 2014 Oral phosphate loading and calcitriol stimulate Fibroblast growth factor 23 (FGF23) secretion, but the mechanisms underlying the stimulation of FGF23 remain to be studied.
Noriko Arai-Nunota +10 more
doaj +1 more source
Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients
Journal of Techniques, 2022 Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue.
Ghaith Hamza Kamil +2 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Tzu Chi Medical Journal, 2021 Objective: Homeostasis of serum phosphorus and calcitriol level is regulated mainly by fibroblast growth factor 23 (FGF23). Studies show that elevated serum FGF23 level was significantly associated with aortic calcification severity, peripheral blood ...
Riri Andri Muzasti, Netty Delvrita Lubis
doaj +1 more source
Cardiac actions of fibroblast growth factor 23 [PDF]
Bone, 2017 Fibroblast growth factors (FGF) are mitogenic signal mediators that induce cell proliferation and survival. Although cardiac myocytes are post-mitotic, they have been shown to be able to respond to local and circulating FGFs. While precise molecular mechanisms are not well characterized, some FGF family members have been shown to induce cardiac ...
openaire +2 more sources
Fibroblast Growth Factor-23 and Outcomes [PDF]
Journal of the American Society of Nephrology, 2013 Even after taking into account comorbidities, such as a diabetes and hypertension, that often accompany CKD, patients are plagued by a high risk of early mortality, particularly because of cardiovascular disease (CVD).[1][1] Focus on traditional risk factors from the general population, such ...
Ishir, Bhan, Ravi, Thadhani
openaire +2 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Einstein (São Paulo)Objective To examine the association of between serum fibroblast growth factor 23 and the functional capacity among independent individuals, aged 80 or older.
Lara Miguel Quirino Araújo +8 more
doaj +2 more sources