Results 41 to 50 of about 961,893 (364)

Hyperphosphatemic Tumoral Calcinosis With Pemigatinib Use

AACE Clinical Case Reports, 2022
Background/Objective: Pemigatinib, a fibroblast growth factor receptor (FGFR) 1-3 inhibitor, is a novel therapeutic approach for treating cholangiocarcinoma when an FGFR fusion or gene rearrangement is identified.
Akshan Puar, MBBS, Diane Donegan, MD, Paul Helft, MD, Matthew Kuhar, MD, Jonathan Webster, MD, Megana Rao, BS, Michael Econs, MD   +6 more
doaj  

A rare cause of atraumatic fractures: case series of four patients with tumor-induced osteomalacia

Clinical Diabetes and Endocrinology, 2020
Background Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome that presents with hypophosphatemia, bone pain, muscle weakness and fractures.
Debbie W. Chen, Gregory A. Clines, Michael T. Collins, Liselle Douyon, Palak U. Choksi   +4 more
doaj   +1 more source

The potential impact of the hypovitaminosis D on metabolic complications in obese adolescents - Preliminary results [PDF]

, 2017
Introduction and Objective Vitamin D deficiency is common in obesity; however, its contribution in the development of metabolic complications remains uncertain.
Januś, Dominika, Kalicka-Kasperczyk, Anna, Starzyk, Jerzy, Sztefko, Krystyna, Wójcik, Małgorzata   +4 more
core   +3 more sources

Fibroblast Growth Factor 23 and Klotho in AKI [PDF]

Seminars in Nephrology, 2019
Acute kidney injury (AKI) is associated with many of the same mineral metabolite abnormalities that are observed in chronic kidney disease. These include increased circulating levels of the osteocyte-derived, vitamin D-regulating hormone, fibroblast growth factor 23 (FGF23), and decreased renal expression of klotho, the co-receptor for FGF23.
David E. Leaf, Sanjeev Gupta, Javier A. Neyra, Marta Christov   +3 more
openaire   +2 more sources

FGF-23 (Fibroblast Growth Factor-23) and Cardiorenal Interactions

Circulation: Heart Failure, 2021
Background: Animal models implicate FGF-23 (fibroblast growth factor-23) as a direct contributor to adverse cardiorenal interactions such as sodium avidity, diuretic resistance, and neurohormonal activation, but this has not been conclusively demonstrated in humans.
F. Perry Wilson, Jeffrey M. Turner, Jeffrey M. Testani, Michael G. Shlipak, Veena S. Rao, Juan Betuel Ivey-Miranda, Juan Betuel Ivey-Miranda, Olyvia Gleason, Julieta Moreno-Villagomez, Julieta Moreno-Villagomez, Christopher Maulion, Wendy McCallum, Grace Meegan, B. Stewart, Jonathan G. Amatruda, Devin Mahoney, Zachary L. Cox, Michelle M. Estrella   +17 more
openaire   +5 more sources

Phosphorus Restriction Changes the Expression of Fibroblast Growth Factor 23 and Its Receptors in Laying Hens

Frontiers in Physiology, 2020
Dietary phosphorus oversupply wastes non-renewable natural resources and raises environmental concerns in animal agriculture. We hypothesized that laying hens do not need large safety margins for dietary phosphorus because of the existence of fibroblast ...
Zhouzheng Ren, Jiakun Yan, Qianli Hu, Xinshuai Liu, Chong Pan, Yanli Liu, Xiaozhen Zhang, Xin Yang, Xiaojun Yang   +8 more
doaj   +1 more source

Fibroblast-growth factor 23 promotes terminal differentiation of ATDC5 cells. [PDF]

PLoS ONE, 2017
Fibroblast Growth Factor 23 (FGF23) is well documented as a crucial player in the systemic regulation of phosphate homeostasis. Moreover, loss-of-function experiments have revealed that FGF23 also has a phosphate-independent and local impact on ...
Mathilde Guibert, Adeline Gasser, Hervé Kempf, Arnaud Bianchi   +3 more
doaj   +1 more source

Role of Fibroblast Growth Factor 23 (FGF23) and αKlotho in Cancer

Frontiers in Cell and Developmental Biology, 2021
Together with fibroblast growth factors (FGFs) 19 and 21, FGF23 is an endocrine member of the family of FGFs. Mainly secreted by bone cells, FGF23 acts as a hormone on the kidney, stimulating phosphate excretion and suppressing formation of 1,25(OH)2D3 ...
Franz Ewendt, Martina Feger, Michael Föller   +2 more
doaj   +1 more source

Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique [PDF]

Iraqi Journal of Veterinary Sciences, 2023
Animal public health is crucial concern when considering the role of fibroblast growth factor-23 (FGF-23) in regulating phosphate metabolism. FGF-23 has been associated with to various diseases in animal, such as chronic kidney and cardiovascular disease,
Soulaf J. Kakel, Ayman M. Albanna
doaj   +1 more source

Intact fibroblast growth factor 23 and fragments in plasma from Gambian children [PDF]

, 2012
SUMMARY: Fibroblast growth factor 23 (FGF23) is grossly elevated in Gambian children with rickets and, at a lower prevalence, in those without bone deformities.
A. Prentice, S. F. A. Bruggraber, V. Braithwaite   +2 more
core   +1 more source