Results 191 to 200 of about 665,368 (391)

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber‐Unkel, Annette Affolter, Paul Gatenholm, Nicole Rotter, Karen Bieback   +7 more
wiley   +1 more source

Molecular cloning and expression of the acidic fibroblast growth factor receptors in a rat parathyroid cell line (PT-r). Parathyroid cell-specific calcium-dependent change of ligand accessibility and covalent attachment of heparan sulfate glycosaminoglycan to the receptors.

, 1994
Y. Takagi, S. Shrivastav, T Miki, Kazushige Sakaguchi   +3 more
openalex   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer. [PDF]

Sci Rep, 2023
Saridogan T, Akcakanat A, Zhao M, Evans KW, Yuca E, Scott S, Kirby BP, Zheng X, Ha MJ, Chen H, Ng PKS, DiPeri TP, Mills GB, Rodon Ahnert J, Damodaran S, Meric-Bernstam F.   +15 more
europepmc   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

Substitution of putative half-cystine residues in heparin-binding fibroblast growth factor receptors. Loss of binding activity in both two and three loop isoforms.

, 1992
Jinzhao Hou, M Kan, Fang Wang, Jianjun Xu, M. Nakahara, G McBride, Kerstin McKeehan, Wallace L. McKeehan   +7 more
openalex   +1 more source

The 16-kDa Proteolytic Fragment of Insulin-Like Growth Factor (IGF) Binding Protein-3 Inhibits the Mitogenic Action of Fibroblast Growth Factor on Mouse Fibroblasts with a Targeted Disruption of the Type 1 IGF Receptor Gene [PDF]

, 1997
Sarah Mohseni Zadeh
openalex   +1 more source

Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor

Heliyon
Fibroblast growth factors and their receptors (FGFR) have major roles in both human growth and oncogenesis. In adults, therapeutic FGFR inhibitors have been successful against tumors that carry somatic FGFR mutations.
Fataneh Majlessipour, Gaohui Zhu, Nicole Baca, Meenasri Kumbaji, Vivian Hwa, Moise Danielpour   +5 more
doaj  

Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells.

, 1994
Taly R. Spivak-Kroizman, Moosa Mohammadi, Patrick J Hu, Michael Jaye, Joseph Schlessinger, Irit Lax   +5 more
openalex   +1 more source

Fibroblast growth factor receptor expression reflects cellular differentiation in human oral squamous carcinoma cell lines [PDF]

, 1998
C S Drugan
openalex   +1 more source