Results 351 to 360 of about 665,368 (391)

Fibroblast Growth Factor and Epidermal Growth Factor Receptors in Ligament Healing

Clinical Orthopaedics and Related Research, 1997
Although recent in vivo studies indicate that basic fibroblast growth factor hastens the healing and strength of the medical collateral ligament after injury, in vitro studies with epidermal growth factor and basic fibroblast growth factor have shown increased fibroblast proliferation with the exogenous administration of these growth factors.
Stephen H. Liu, Gerald A. M. Finerman, Joseph M. Lane, Vah Panossian   +3 more
openaire   +3 more sources

Fibroblast Growth Factors and Their Receptors in Hematopoiesis and Hematological Tumors

Journal of Hematotherapy & Stem Cell Research, 2002
Fibroblast growth factors (FGFs) belong to a family of pleiotropic heparin-binding growth factors. They exert multiple functions on various cell types of mesodermal and neuroectodermal origin, affecting cell proliferation, motility, survival, and differentiation.
MORONI E., DELL'ERA, Patrizia, RUSNATI, Marco, PRESTA, Marco   +3 more
openaire   +4 more sources

The ins and outs of fibroblast growth factor receptor signalling.

Clinical science, 2014
FGFR (fibroblast growth factor receptor) signalling plays critical roles in embryogensis, adult physiology, tissue repair and many pathologies. Of particular interest over recent years, it has been implicated in a wide range of cancers, and concerted ...
Stacey J. Coleman, Charo Bruce, A. Chioni, H. Kocher, R. Grose   +4 more
semanticscholar   +1 more source

Expression of fibroblast growth factor 10 and its receptor, fibroblast growth factor receptor 2B, in the bovine corpus luteum

Molecular Reproduction and Development, 2007
AbstractThere is evidence that several fibroblast growth factors (FGFs) are involved in growth and development of the corpus luteum (CL), but many FGFs have not been investigated in this tissue, including FGF10. The objective of this study was to determine if FGF10 and its receptor (FGFR2B) are expressed in the CL.
Castilho, A. C., Giometti, I. C., Berisha, B., Schams, D., Price, C. A., Amorim, Renée Laufer, Papa, P. C., Buratini, J.   +7 more
openaire   +4 more sources

Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2).

Developmental Biology, 1993
The gene for fibroblast growth factor receptor-2 (FGFR2) encodes two splice variants designated here as keratinocyte growth factor (KGFR) and bek. Their ligand-binding specificity is markedly different due to mutually exclusive alternative splicing.
A. Orr-Urtreger, M. Bedford, T. Burakova, E. Arman, Y. Zimmer, A. Yayon, D. Givol, P. Lonai   +7 more
semanticscholar   +1 more source

Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas

Journal of Neuro-Oncology, 1994
Malignant astrocytomas are highly invasive, vascular neoplasms that comprise the majority of nervous system tumors in humans. A strong association has previously been made between malignancy in human astrocytic tumors and increased expression of certain fibroblast growth factor (FGF) family members, including basic and acidic FGF.
Fumio Yamaguchi, Mitchel S. Berger, Richard S. Morrison, Hideyuki Saya, Janet M. Bruner, Lawrence A. Donehower, Alan M. Yahanda   +6 more
openaire   +3 more sources

Immunclocalization of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptor-1 and Receptor-2 in Rat Cranial Sutures

Plastic and Reconstructive Surgery, 1998
Craniosynostosis is a common disorder with an unknown etiology. Recent genetic mapping studies have demonstrated a strong linkage between several familial craniosynostotic syndromes and mutations in fibroblast growth factor receptor 1 (FGF-R1) and 2 (FGF-R2).
Michael T. Longaker, George K. Gittes, Babak J. Mehrara, Richard J. Mackool, Joseph G. McCarthy   +4 more
openaire   +3 more sources

Angiogenesis, Fibroblast Growth Factors, and Their Receptors

1999
The key determinants defining the earliest events in angiogenesis, vas-culogenesis, and the molecular differences that distinguish arteries from veins are now better understood than at any time to date. The adult vasculature consists of large arteries that progressively branch into smaller and smaller vessels terminating into precapillary arterioles ...
openaire   +2 more sources

Modulation of the epidermal growth factor receptor by basic fibroblast growth factor

Journal of Cellular Physiology, 1993
AbstractTreatment of Swiss 3T3 fibroblasts with basic fibroblast growth factor (bFGF) lead to a rapid reduction in epidermal growth factor (EGF) binding and a slower inhibition of EGF receptor autophosphorylation. The reduction in binding was due to a complete loss of the highest affinity EGF binding sites and a reduction in the lower affinity binding ...
openaire   +3 more sources

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly