Results 31 to 40 of about 10,651,893 (289)

Novel parameter for cancer chemosensitivity to fibroblast growth factor receptor inhibitors

Cancer Science, 2022
AbstractFibroblast growth factor receptor inhibitors (FGFRi) were introduced into clinical trials on several cancer types and found to be particularly efficacious on urothelial cancer and cholangiocarcinoma. Although many enrolled patients responded well in clinical trials, there were some patients who did not respond to FGFRi even though their tumors ...
Shoichi Kitano, Takehito Yamamoto, Makoto Mark Taketo   +2 more
openaire   +2 more sources

Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist

Journal of Nanobiotechnology, 2023
Acne is a chronic skin condition that has serious consequences for mental and social well-being because it frequently occurs on the face. Several acne treatment approaches have commonly been used but have been hampered by side effects or weak activity ...
Zijian Su, Yibo Zhang, Jieqiong Cao, Yuanmeng Sun, Yuling Cai, Bihui Zhang, Liu He, Zilei Zhang, Junye Xie, Qilin Meng, Lin Luo, Fu Li, Jingsheng Li, Jinting Zhang, Xiaojia Chen, An Hong   +15 more
doaj   +1 more source

FGFR1 (Fibroblast Growth Factor Receptor 1) [PDF]

, 2009
Review on FGFR1 (Fibroblast Growth Factor Receptor 1), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL
core   +1 more source

Vascular Targeted Agents for the Treatment of Angiosarcoma [PDF]

, 2013
Background: Angiogenesis is the process of new blood vessel formation, and is regulated by angiogenic growth factors including vascular endothelial growth factor (VEGF). Angiosarcomas are rare, aggressive vascular tumours.
P J Woll (16226153), R J Young (13425891), C A Staton (16226156), Malcolm Reed (4465876), Young, Robin, N J Brown (13424178)   +5 more
core   +5 more sources

FGFR4 (fibroblast growth factor receptor 4) [PDF]

, 2012
Review on FGFR4 (fibroblast growth factor receptor 4), with data on DNA, on the protein encoded, and where the gene is ...
Barderas, Rodrigo, Peláez-García, Alberto, Peláez-García, A, Casal, JI, Casal, J. Ignacio, Barderas, R   +5 more
core   +1 more source

The future of fibroblast growth factor receptor inhibitors and mechanisms of resistance for cholangiocarcinoma

Expert Opinion on Pharmacotherapy, 2023
Cholangiocarcinoma (CCA) is a rare cancer that arises from the biliary tract. Despite advances in multimodal treatment, patients with CCA have a poor prognosis. Molecular profiling of CCA has identified unique genetic aberrations (GA) that may serve as therapeutic targets. A common GA in CCA is in the fibroblast growth factor receptors (FGFR).
Samantha M, Ruff, Sameek, Roychowdhury, Timothy M, Pawlik   +2 more
openaire   +2 more sources

FGFR2 (fibroblast growth factor receptor 2) [PDF]

, 2009
Review on FGFR2 (fibroblast growth factor receptor 2), with data on DNA, on the protein encoded, and where the gene is ...
Katoh, M
core   +1 more source

FGFR blockade inhibits targeted therapy-tolerant persister in basal FGFR1- and FGF2-high cancers with driver oncogenes

npj Precision Oncology, 2023
Cancer cell resistance arises when tyrosine kinase inhibitor (TKI)-targeted therapies induce a drug-tolerant persister (DTP) state with growth via genetic aberrations, making DTP cells potential therapeutic targets.
Koh Furugaki, Takaaki Fujimura, Hayato Mizuta, Takuya Yoshimoto, Takashi Asakawa, Yasushi Yoshimura, Shigeki Yoshiura   +6 more
doaj   +1 more source

FGFR3 (fibroblast growth factor receptor 3) [PDF]

, 1998
Review on FGFR3 (fibroblast growth factor receptor 3), with data on DNA, on the protein encoded, and where the gene is ...
Bonaventure, J
core   +1 more source

FGFR1 (fibroblast growth factor receptor 1) [PDF]

, 1998
Review on FGFR1 (fibroblast growth factor receptor 1), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL
core   +1 more source