Results 261 to 270 of about 2,052,125 (407)

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects. [PDF]

open access: green, 1988
Margaret Bywater   +7 more
openalex   +1 more source

Klotho and fibroblast growth factors 19 and 21 serum concentrations in children and adolescents with normal body weight and obesity and their associations with metabolic parameters. [PDF]

open access: yesBMC Pediatr, 2020
Socha-Banasiak A   +9 more
europepmc   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella   +9 more
wiley   +1 more source

Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts.

open access: bronze, 1987
Leif R. Lund   +8 more
openalex   +1 more source

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