Results 61 to 70 of about 1,904,768 (328)

Implication of fibroblast growth factors in epileptogenesis-associated circuit rearrangements

Frontiers in Cellular Neuroscience, 2013
The transformation of a normal brain in epileptic (epileptogenesis) is associated with extensive morpho-functional alterations, including cell death, axonal and dendritic plasticity, neurogenesis, and others. Neurotrophic factors (NTFs) appear to be very
Beatrice eParadiso, Silvia eZucchini, Michele eSimonato   +2 more
doaj   +1 more source

System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. [PDF]

PLoS Genetics, 2013
Many fibroblast-secreted proteins promote tumorigenicity, and several factors secreted by cancer cells have in turn been proposed to induce these proteins.
Megha Rajaram, Jinyu Li, Mikala Egeblad, R Scott Powers   +3 more
doaj   +1 more source

Semen Modulates Cell Proliferation and Differentiation-Related Transcripts in the Pig Peri-Ovulatory Endometrium

Biology, 2022
Uterine homeostasis is maintained after mating by eliminating pathogens, foreign cells, and proteins by a transient inflammation of the uterus. Such inflammation does not occur in the oviductal sperm reservoir (utero-tubal junction, UTJ), colonized by a ...
Jaume Gardela, Mateo Ruiz-Conca, Dominic Wright, Manel López-Béjar, Cristina A. Martínez, Heriberto Rodríguez-Martínez, Manuel Álvarez-Rodríguez   +6 more
doaj   +1 more source

Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment [PDF]

, 2017
The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells.
Galemmo, Robert, Janetka, James, Klampfer, Lidija, Owusu, Benjamin Yaw   +3 more
core   +2 more sources

Fibroblast growth factor 2

Differentiation
Fibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation.
Audrey Nickle, Sebastian Ko, Amy E. Merrill   +2 more
openaire   +3 more sources

Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes [PDF]

, 2010
Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
core   +1 more source

Fibroblast growth factor receptor 4 single nucleotide polymorphism Gly388Arg in head and neck carcinomas [PDF]

, 2019
BACKGROUND Head and neck squamous cell carcinoma (HNSCC) is considered to be a progressive disease resulting from alterations in multiple genes regulating cell proliferation and differentiation like receptor tyrosine kinases (RTKs) and members of the ...
Bergmann, C., Gires, O., Ihrler, S., Issing, W., Streit, S., Wimmer, E.   +5 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Functional Diversity of Fibroblast Growth Factors in Bone Formation

International Journal of Endocrinology, 2015
The functional significance of fibroblast growth factor (FGF) signaling in bone formation has been demonstrated through genetic loss-of-function and gain-of-function approaches.
Yuichiro Takei, Tomoko Minamizaki, Yuji Yoshiko   +2 more
doaj   +1 more source

Responses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice

Frontiers in Cell and Developmental Biology, 2021
Placodes are ectodermal thickenings of the embryonic vertebrate head. Their descendants contribute to sensory organ development, but also give rise to sensory neurons of the cranial nerves.
Stefan Washausen, Wolfgang Knabe
doaj   +1 more source