Results 161 to 170 of about 554,180 (264)

Direct aldosterone stimulation of skeletal muscle fibroblasts changes gene expression and differentially affects fibroblast functions from normal and diseased muscles. [PDF]

Front Physiol
Gomatam CK, Krishna S, Lowe J, Silver E, Lepper C, Rafael-Fortney JA.   +5 more
europepmc   +1 more source

Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials

Advanced Healthcare Materials, EarlyView.
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores, Eva Mueller, Robert Bui, James C. Fredenburgh, Ruiqi Yin, Rawaa Hussain, Rida A. Malik, Thomas Kalab, Dabeer Abdul‐Azeez, Fei Xu, Michael Brook, Jeffrey I. Weitz, Todd Hoare   +12 more
wiley   +1 more source

Epicardial Contributions to Fibro-Inflammatory Signaling in a Pkp2-Deficient Arrhythmogenic Cardiomyopathy Model. [PDF]

Circ Heart Fail
Han DD, Brooks AC, Baker CD, Dirkx RA, Mickelsen DM, Fisler B, Phadke K, Ashton JM, Delmar M, Small EM.   +9 more
europepmc   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Optimisation of low-level light therapy (lllt) parameters and evaluation of its immunomodulatory effect on fibroblasts. [PDF]

Lasers Med Sci
Ścisłowska-Czarnecka A, Lizak A, Matuła A, Bac A, Homa J, Chadzińska M, Stenka B.   +6 more
europepmc   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Human germline biallelic loss-of-function <i>OSMR</i> variants cause severe allergic disease. [PDF]

J Hum Immun
Samra S, Sharma M, Körholz J, Liu Y, James A, Michalski C, Yousefi P, Del Bel KL, Lu HY, Sharma AA, Tarailo-Graovac M, Dalmann J, Buder L, Modi B, Wiedemuth R, Golding L, Drögemöller B, Blanchard-Rohner G, Senger C, Rehmus W, Prendiville JS, Mangino M, Ross CJ, van Karnebeek CDM, Wasserman WW, D Rosenzweig S, Niemela J, Lavoie PM, Prathibha PM, Wegehaupt O, Biggs CM, Boehnke M, Kinnunen L, Koistinen HA, McKinnon ML, Breuer JM, Schönenkorb J, Brock R, Thull S, Netzer C, Velmans C, Altuwaijri N, Hamadah IR, Altassan R, Alfares A, Maddirevula S, Patil SJ, Bayer DK, Lyons JJ, Turvey SE.   +49 more
europepmc   +1 more source

Fibroblast [PDF]

, 2019
openaire   +1 more source

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

Dynamic Reprogramming of PDGFRA-Expressing Stromal Cells Facilitates WNT-Driven Transformation by Promoting a Fetal-Like State in the Intestinal Epithelium. [PDF]

Cancer Res
Pellon-Cardenas O, Rout P, Hassan S, Fokas E, Patel I, Patel J, Qiu X, He P, Nussbaum O, Wu A, Kumar R, Akther M, Logerfo A, Wu S, Wagner D, Boffelli D, Walton KD, Tong K, Iqbal J, Xiao R, Chen L, Spence JR, Bessman NJ, Manieri E, Shivdasani RA, Verzi MP.   +25 more
europepmc   +1 more source