Results 11 to 20 of about 988,166 (377)

AGE AND MULTIPLICATION OF FIBROBLASTS [PDF]

open access: bronzeJournal of Experimental Medicine, 1921
Pure cultures of fibroblasts displayed marked differences in their activity in the plasma of young, middle aged, and old chickens. The rate of cell multiplication varied in inverse ratio to the age of the animal from which the plasma was taken. There was a definite relation between the age of the animal and the amount of new tissue produced in its ...
Alexis Carrel, Albert H. Ebeling
openalex   +5 more sources

A Fibroblast Is Not a Fibroblast Is Not a Fibroblast [PDF]

open access: yesJournal of Investigative Dermatology, 2018
Fibrosis after injury is a huge public health concern, leading to morbidity, mortality, and expenditure of billions of health care dollars. Recent mouse studies have shown that dermal fibroblasts are heterogeneous. New research using single-cell RNA sequencing to identify major fibroblast populations in humans is paving the way to a better ...
Michael S. Hu   +2 more
openaire   +3 more sources

β2‐adrenergic stimulation induces interleukin‐6 by increasing Arid5a, a stabilizer of mRNA, through cAMP/PKA/CREB pathway in cardiac fibroblasts

open access: yesPharmacology Research & Perspectives, 2020
Background and Purpose In cardiovascular diseases, cardiac fibroblasts (CFs) participate in the myocardial inflammation by producing pro‐inflammatory cytokines, worsening the prognosis.
Shota Tanaka   +5 more
doaj   +1 more source

Advanced Glycation End Products in the Skin: Molecular Mechanisms, Methods of Measurement, and Inhibitory Pathways

open access: yesFrontiers in Medicine, 2022
Advanced glycation end products (AGEs) are a series of stable compounds produced under non-enzymatic conditions by the amino groups of biomacromolecules and the free carbonyl groups of glucose or other reducing sugars commonly produced by thermally ...
Chun-yu Chen   +23 more
doaj   +1 more source

The MicroRNA miR-155 Is Essential in Fibrosis

open access: yesNon-Coding RNA, 2019
The function of microRNAs (miRNAs) during fibrosis and the downstream regulation of gene expression by these miRNAs have become of great biological interest.
Mousa G. Eissa, Carol M. Artlett
doaj   +1 more source

Human Lung Fibroblasts Exhibit Induced Inflammation Memory via Increased IL6 Gene Expression and Release

open access: yesFrontiers in Immunology, 2022
Fibroblasts of different origins are known to possess stromal memory after inflammatory episodes. However, there are no studies exploring human lung fibroblast memory which may predict a subsequent inflammatory response in chronic respiratory diseases ...
Jennifer Maries Go Yap   +13 more
doaj   +1 more source

Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling [PDF]

open access: yes, 2021
The analytical theory of our earlier study (Mortensen et al. (2021), Mathematical Medicine and Biology, 38(1), pp. 106-131) is extended to address the outstanding cases of fibroblast barrier distribution and myocyte strait distribution. In particular, closed-form approximations to the resting membrane potential and to the critical parameter values for ...
arxiv   +1 more source

Therapeutic induction of Bcl2‐associated athanogene 3‐mediated autophagy in idiopathic pulmonary fibrosis

open access: yesClinical and Translational Medicine, 2022
Background Exaggerated fibroblast proliferation is a well‐known feature in idiopathic pulmonary fibrosis (IPF) which may be – in part – due to insufficient autophagy, a lysosome dependent cellular surveillance pathway. Bcl2‐associated athanogene 3 (BAG3)
Shashipavan Chillappagari   +10 more
doaj   +1 more source

Biodentine stimulates the migratory and biological responses of human gingival fibroblast

open access: yesJournal of Oral Research, 2022
Introduction: Biodentine (BD), a dentin substitute, is currently used to treat external cervical root resorption, but its effects on gingival fibroblasts (GFs) are not fully known. Objective: To investigate and compare BD and MTA (mineral trioxide aggre-
Febe Vázquez-Vázquez   +4 more
doaj   +1 more source

PU.1 controls fibroblast polarization and tissue fibrosis [PDF]

open access: yes, 2019
Fibroblasts are polymorphic cells with pleiotropic roles in organ morphogenesis, tissue homeostasis and immune responses. In fibrotic diseases, fibroblasts synthesize abundant amounts of extracellular matrix, which induces scarring and organ failure.
Beyer, Christian   +33 more
core   +1 more source

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