Results 31 to 40 of about 946,310 (305)

Expression of proliferation-dependent antigens during cellular ageing of normal and progeroid human fibroblasts [PDF]

, 1994
Normal human fibroblasts display a limited lifespan in culture, which is due to a steadily decreasing fraction of cells that are able to proliferate.
Faragher, RA, Kill, IR, Lawrence, KM, Shall, S   +3 more
core  

Equine sarcoids: Bovine Papillomavirus type 1 transformed fibroblasts are sensitive to cisplatin and UVB induced apoptosis and show aberrant expression of p53 [PDF]

, 2012
Bovine papillomavirus type 1 infects not only cattle but also equids and is a causative factor in the pathogenesis of commonly occurring equine sarcoid tumours.
Campo, M., Finlay, M., Morgan, I.M., Nasir, L., Yuan, Z.   +4 more
core   +3 more sources

Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Background: Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by GAA repeat expansion in the first intron of the FXN gene, which encodes
A Durr, A Filla, A Halabi, A Hick, A Rotig, A Wong, AH Koeppen, AL Bulteau, AM Khalil, Annalisa Pastore, BL Sopher, C Gellera, C Sandi, CH Zuhlke, Chiranjeevi Sandi, D Marmolino, D Marmolino, D Waldvogel, DH Cho, DW Chung, E Greene, F Foury, G Coppola, G Tan, GS Chandok, H Holemon, H Puccio, H Puccio, H Van Remmen, Harvinder Jassal, I Castaldo, I De Biase, I De Biase, J Du, J Liu, J St-Pierre, JB Schulz, JH Willis, JL Bradley, JL García-Giménez, JP Sarsero, L Grant, L Montermini, L Pianese, L Schols, M Anheim, M Cossee, M Pandolfo, M Perdomini, MA Pook, Madhavi Sandi, Mark A. Pook, ML Moseley, MM Heidari, MM Lufino, MV Evans-Galea, MV Evans-Galea, N Calmels, N Sakamoto, PD Ladd, R Sharma, RA Vaubel, RL Bourn, RM Clark, S Al-Mahdawi, S Al-Mahdawi, S Al-Mahdawi, S Al-Mahdawi, S Ku, Sahar Al-Mahdawi, Sara Anjomani-Virmouni, SW Levison, T Geng, V Campuzano, V Campuzano, V Ezzatizadeh, Vahid Ezzatizadeh, Y Shan   +77 more
core   +6 more sources

Fibroblastic Rheumatism

Indian Journal of Rheumatology, 2017
Fibroblastic rheumatism (FR) is a rare dermoarthopathy reported from different parts of the world since 1980. Although the exact cause is unknown, few reports implicate infection may be a triggering event. Patients usually present with multiple skin nodules and polyarthropathy with progressive skin contractures.
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reproducibility and Consistency of Isolation Protocols for Fibroblasts, Smooth Muscle Cells, and Epithelial Cells from the Human Vagina

Cells
(1) Background: For the reconstruction of a human vagina, various surgical procedures are available that are often associated with complications due to their failure to mimic the physiology of the human vagina. We recently developed a vascularized, organ-
Jayson Sueters, Rogier Schipperheijn, Judith Huirne, Theo Smit, Zeliha Guler   +4 more
doaj   +1 more source

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons [PDF]

, 2015
Patient-derived induced Pluripotent Stem Cells (iPSCs) provide an opportunity to study human diseases mainly in those cases where no suitable model systems are available.
Bozzoni, Irene, Caliendo, Virginia, Calvo, Andrea, Chiò, Adriano, DE SANTIS, Riccardo, Laneve, Pietro, Lenzi, Jessica, Morlando, Mariangela, Rosa, Alessandro, Turris, Valeria de   +9 more
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Joint use of developed collagen-containing complexes and cell cultures in creating new tissue equivalents

Бюллетень сибирской медицины, 2017
The purpose of the study is to assess the possibility of applying the integrated module as the basis of a celltissue equivalent for treatment of wounds of skin and soft tissues.
K. V. Kulakova, D. Ya. Aleynik, I. N. Charykova   +2 more
doaj   +1 more source

Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction

JACC: Basic to Translational Science, 2023
Summary: Irreversible fibrosis is a hallmark of myocardial infarction (MI) and heart failure. Extracellular matrix protein-1 (ECM-1) is up-regulated in these hearts, localized to fibrotic, inflammatory, and perivascular areas.
Sean A. Hardy, PhD, Laura Liesinger, MSc, Ralph Patrick, PhD, Maria Poettler, PhD, Lavinia Rech, MD, Juergen Gindlhuber, PhD, Nishani S. Mabotuwana, BBmedHons, DiyaaEldin Ashour, PhD, Verena Stangl, MD, Mark Bigland, PhD, Lucy A. Murtha, PhD, Malcolm R. Starkey, PhD, Daniel Scherr, MD, Philip M. Hansbro, PhD, Gerald Hoefler, MD, Gustavo Campos Ramos, PhD, Clement Cochain, PhD, Richard P. Harvey, PhD, Ruth Birner-Gruenberger, PhD, Andrew J. Boyle, PhD, Peter P. Rainer, MD, PhD   +20 more
doaj   +1 more source