Results 11 to 20 of about 554,180 (264)

Study of the physical and biological properties of nanocomposite materials obtained with laser radiation

Сеченовский вестник, 2021
The new method of the formation of nanocomposite materials based on carbon nanotubes for the regeneration of connective tissues has been developed.Aim.
U. E. Kurilova, A. Yu. Gerasimenko
doaj   +1 more source

Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice

Cells, 2022
PIEZO1 is a subunit of mechanically-activated, nonselective cation channels. Gain-of-function PIEZO1 mutations are associated with dehydrated hereditary stomatocytosis (DHS), a type of anaemia, due to abnormal red blood cell function.
Fiona Bartoli, Elizabeth L. Evans, Nicola M. Blythe, Leander Stewart, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Katie E. Musialowski, Laeticia Lichtenstein, Gregory Parsonage, T. Simon Futers, Neil A. Turner, David J. Beech   +11 more
doaj   +1 more source

Heterogenecity of fibroblasts

Journal of Oral and Maxillofacial Pathology, 2011
Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete cellular subsets.
Ravikanth, Manyam, Soujanya, P, Manjunath, K, Saraswathi, TR, Ramachandran, CR   +4 more
openaire   +3 more sources

A triple co-culture method to investigate the effect of macrophages and fibroblasts on myoblast proliferation and migration

BioTechniques, 2018
The communication between nonmyogenic cells, such as macrophages and fibroblasts, and myoblasts is crucial for successful skeletal muscle repair. In vitro co-culture methods can be used to increase our understanding of these cellular interactions ...
Colin Venter, Carola Niesler
doaj   +1 more source

Effect of Verapamil on the formation of adhesions in aseptic peritonitis

Бюллетень сибирской медицины, 2017
Objective. An experimental study of verapamil new properties, such as the regulation of the connective tissue formation.Materials and мethods. The study was conducted in an aseptic inflammation of the peritoneum both on the body and cell culture in ...
Sergey V. Skalskiy, Tatyana F. Sokolova, Dmitriy A. Sychev, Nadezhda E. Turok   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reproducibility and Consistency of Isolation Protocols for Fibroblasts, Smooth Muscle Cells, and Epithelial Cells from the Human Vagina

Cells
(1) Background: For the reconstruction of a human vagina, various surgical procedures are available that are often associated with complications due to their failure to mimic the physiology of the human vagina. We recently developed a vascularized, organ-
Jayson Sueters, Rogier Schipperheijn, Judith Huirne, Theo Smit, Zeliha Guler   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Joint use of developed collagen-containing complexes and cell cultures in creating new tissue equivalents

Бюллетень сибирской медицины, 2017
The purpose of the study is to assess the possibility of applying the integrated module as the basis of a celltissue equivalent for treatment of wounds of skin and soft tissues.
K. V. Kulakova, D. Ya. Aleynik, I. N. Charykova   +2 more
doaj   +1 more source

Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction

JACC: Basic to Translational Science, 2023
Summary: Irreversible fibrosis is a hallmark of myocardial infarction (MI) and heart failure. Extracellular matrix protein-1 (ECM-1) is up-regulated in these hearts, localized to fibrotic, inflammatory, and perivascular areas.
Sean A. Hardy, PhD, Laura Liesinger, MSc, Ralph Patrick, PhD, Maria Poettler, PhD, Lavinia Rech, MD, Juergen Gindlhuber, PhD, Nishani S. Mabotuwana, BBmedHons, DiyaaEldin Ashour, PhD, Verena Stangl, MD, Mark Bigland, PhD, Lucy A. Murtha, PhD, Malcolm R. Starkey, PhD, Daniel Scherr, MD, Philip M. Hansbro, PhD, Gerald Hoefler, MD, Gustavo Campos Ramos, PhD, Clement Cochain, PhD, Richard P. Harvey, PhD, Ruth Birner-Gruenberger, PhD, Andrew J. Boyle, PhD, Peter P. Rainer, MD, PhD   +20 more
doaj   +1 more source