Results 11 to 20 of about 28,494 (215)
A Fibroblast Is Not a Fibroblast Is Not a Fibroblast [PDF]
Journal of Investigative Dermatology, 2018 Fibrosis after injury is a huge public health concern, leading to morbidity, mortality, and expenditure of billions of health care dollars. Recent mouse studies have shown that dermal fibroblasts are heterogeneous. New research using single-cell RNA sequencing to identify major fibroblast populations in humans is paving the way to a better ...
Michael S, Hu +2 more
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BioTechniques, 2018 The communication between nonmyogenic cells, such as macrophages and fibroblasts, and myoblasts is crucial for successful skeletal muscle repair. In vitro co-culture methods can be used to increase our understanding of these cellular interactions ...
Colin Venter, Carola Niesler
doaj +1 more source
Nature Reviews Cancer, 2006 Tumours are known as wounds that do not heal - this implies that cells that are involved in angiogenesis and the response to injury, such as endothelial cells and fibroblasts, have a prominent role in the progression, growth and spread of cancers. Fibroblasts are associated with cancer cells at all stages of cancer progression, and their structural and
Kalluri, Raghu, Zeisberg, Michael
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Journal of Oral and Maxillofacial Pathology, 2011 Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete cellular subsets.
Ravikanth, Manyam +4 more
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Effect of Verapamil on the formation of adhesions in aseptic peritonitis
Бюллетень сибирской медицины, 2017 Objective. An experimental study of verapamil new properties, such as the regulation of the connective tissue formation.Materials and мethods. The study was conducted in an aseptic inflammation of the peritoneum both on the body and cell culture in ...
Sergey V. Skalskiy +3 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Cells(1) Background: For the reconstruction of a human vagina, various surgical procedures are available that are often associated with complications due to their failure to mimic the physiology of the human vagina. We recently developed a vascularized, organ-
Jayson Sueters +4 more
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Бюллетень сибирской медицины, 2017 The purpose of the study is to assess the possibility of applying the integrated module as the basis of a celltissue equivalent for treatment of wounds of skin and soft tissues.
K. V. Kulakova +2 more
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JACC: Basic to Translational Science, 2023 Summary: Irreversible fibrosis is a hallmark of myocardial infarction (MI) and heart failure. Extracellular matrix protein-1 (ECM-1) is up-regulated in these hearts, localized to fibrotic, inflammatory, and perivascular areas.
Sean A. Hardy, PhD +20 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source