Results 21 to 30 of about 988,166 (377)
Control of the skin scarring response
Anais da Academia Brasileira de Ciências, 2009 There comes a time when the understanding of the cutaneous healing process becomes essential due to the need for a precocious tissue repair to reduce the physical, social, and psychological morbidity.
Lydia M. Ferreira +3 more
doaj +1 more source
Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair [PDF]
, 2000 We deveiop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a ...
Dallon, J. C. +3 more
core +1 more source
Cardiac Fibrosis and Fibroblasts [PDF]
Cells, 2021 Cardiac fibrosis is the excess deposition of extracellular matrix (ECM), such as collagen. Myofibroblasts are major players in the production of collagen, and are differentiated primarily from resident fibroblasts. Collagen can compensate for the dead cells produced by injury.
openaire +3 more sources
Peripheral vascular remodeling during ischemia
Frontiers in Pharmacology, 2022 About 230 million people worldwide suffer from peripheral arterial disease (PAD), and the prevalence is increasing year by year. Multiple risk factors, including smoking, dyslipidemia, diabetes, and hypertension, can contribute to the development of PAD.
Shigang Lin +4 more
doaj +1 more source
Stromal cells differentially regulate neutrophil and lymphocyte recruitment through the endothelium [PDF]
, 2010 Stromal fibroblasts modify the initial recruitment of leucocytes by endothelial cells (EC), but their effects on subsequent transendothelial migration remain unclear.
Arisaka +72 more
core +2 more sources
Frontiers in Physiology, 2022 Background: Atrial fibrosis plays an important role in the development and persistence of atrial fibrillation by promoting reentry. Primary cilia have been identified as a regulator of fibroblasts (FB) activation and extracellular matrix (ECM) deposition.
Auriane C. Ernault +7 more
doaj +1 more source
Autocrine Transforming Growth Factor β Signaling Regulates Extracellular Signal-regulated Kinase 1/2 Phosphorylation via Modulation of Protein Phosphatase 2A Expression in Scleroderma Fibroblasts [PDF]
, 2010 BACKGROUND. During scleroderma (SSc) pathogenesis, fibroblasts acquire an activated phenotype characterized by enhanced production of extracellular matrix (ECM) and constitutive activation of several major signaling pathways including extracellular ...
Bujor, Andreea M. +4 more
core +3 more sources
Dental Journal, 2015 Background: Wound healing involves cellular, molecular, physiological, and biochemical processes as responses to tissue damage. For instance, when a failure during tooth extraction occurs, radiographic examination, X-rays, is required.
Fatma Yasmin Mahdani +2 more
doaj +1 more source
Primary skin fibroblasts as a model of Parkinson's disease [PDF]
, 2012 Parkinson's disease is the second most frequent neurodegenerative disorder. While most cases occur sporadic mutations in a growing number of genes including Parkin (PARK2) and PINK1 (PARK6) have been associated with the disease.
A Grunewald +84 more
core +1 more source
Journal of Oral and Maxillofacial Pathology, 2011 Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete cellular subsets.
TR Saraswathi +4 more
openaire +4 more sources