Results 191 to 200 of about 196,664 (232)

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Integrin-specific signaling drives ER stress-dependent atherogenic endothelial activation. [PDF]

Redox Biol
Ben Dhaou C, Al-Yafeai Z, Cruz-Marquez GA, Scott ML, Pearson-Gallion B, Cockerham E, Li H, Peretik JM, Hong Y, Dhanesha N, Yurdagul A, Rom O, Bhuiyan MS, Orr AW.   +13 more
europepmc   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

HuR-Targeted Small Molecules Reduce <i>Pseudomonas aeruginosa</i> Adhesion in Cystic Fibrosis Airway Epithelial Cells. [PDF]

Int J Mol Sci
Listro R, Pellegrini A, Rossino G, Linciano P, Pietrocola G, Collina S.   +5 more
europepmc   +1 more source

Age-Dependent KLK8 Upregulation Contributes to Elevated Susceptibility to Ventilator-Induced Lung Injury in the Elderly Mice. [PDF]

Aging Cell
Liu D, Lin TT, Zhang H, Zhao Y, Xu CF, Liu YJ, Jiang L, Zhu XY.   +7 more
europepmc   +1 more source

Transforming Growth Factor-β-Mediated Fibrotic Remodeling Drives Chronic Kidney Disease in Methylmalonic Aciduria and Propionic Aciduria-Identification of a New Therapeutic Target. [PDF]

J Inherit Metab Dis
Zeyer KA, Tholen S, Schilling O, Gerling L, Morath M, Kölker S, Nyström A, Spiekerkoetter U, Schumann A.   +8 more
europepmc   +1 more source

Loss of fibronectin fiber tension is inherent to ECM remodeling in human myocarditis and post-inflammatory fibrosis. [PDF]

Matrix Biol Plus
Sridhar KC, Mehl J, Klingel K, Thiele M, Van Linthout S, Tschöpe C, Duda GN, Vogel V.   +7 more
europepmc   +1 more source

The NLRP3 inflammasome as a key pathway in the affective and chronic fatigue symptoms of Long COVID. [PDF]

J Transl Med
Zhang Y, Al-Hakeim HK, Al-Jassas HK, Maes M.   +3 more
europepmc   +1 more source