Fibronectin at Select Sites Binds Multiple Growth Factors and Enhances their Activity: Expansion of the Collaborative ECM-GF Paradigm [PDF]
Jia Zhu, Richard A.F. Clark
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An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar +6 more
wiley +1 more source
Molecular Docking and Simulation Analysis of Glioblastoma Cell Surface Receptors and Their Ligands: Identification of Inhibitory Drugs Targeting Fibronectin Ligand to Potentially Halt Glioblastoma Pathogenesis. [PDF]
Khan MWA +6 more
europepmc +1 more source
Fibrinogen controls human platelet fibronectin internalization and cell‐surface retention [PDF]
Zhimin Zhai +7 more
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Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
A cadherin-integrin-ECM code for presomitic mesoderm fluidity. [PDF]
Genuth MA +7 more
europepmc +1 more source
Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen.
Hynda K. Kleinman +2 more
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Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu +12 more
wiley +1 more source
Olive Leaf Extract Added to Losartan Treatment Improved Klotho/Wnt/β-Catenin Signaling in Hypertensive Rats with Focal Segmental Glomerulosclerosis. [PDF]
Karanović D +8 more
europepmc +1 more source
Effects of plasma fibronectin on chemiluminescence of human polymorphonuclear leukocytes
Masayasu Iwase +4 more
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