Results 11 to 20 of about 1,182,877 (363)

Elexacaftor/tezacaftor/ivacaftor as rescue therapy in a patient with the cystic fibrosis genotype F508DEL/G1244E

open access: yesClinical Case Reports, 2021
Elexacaftor/tezacaftor/ivacaftor (ETI) is a cystic fibrosis (CF) transmembrane regulator (CFTR) modulator. It is known to be efficacious in stable patients with severe pneumopathy, but there are few data concerning its effectiveness during acute ...
Donatello Salvatore   +4 more
doaj   +1 more source

Adenosine in fibrosis [PDF]

open access: yesModern Rheumatology, 2009
Adenosine is an endogenous autocoid that regulates a multitude of bodily functions. Its anti-inflammatory actions are well known to rheumatologists since it mediates many of the anti-inflammatory effects of a number of antirheumatic drugs such as methotrexate.
Bruce N. Cronstein, Edwin S. L. Chan
openaire   +3 more sources

Retroperitoneal fibrosis [PDF]

open access: yesThe Lancet, 2006
Retroperitoneal fibrosis encompasses a range of diseases characterised by the presence of a fibro-inflammatory tissue, which usually surrounds the abdominal aorta and the iliac arteries and extends into the retroperitoneum to envelop neighbouring structures--eg, ureters. Retroperitoneal fibrosis is generally idiopathic, but can also be secondary to the
Vaglio, Augusto   +2 more
openaire   +5 more sources

Impact of noise on the instability of spiral waves in stochastic 2D mathematical models of human atrial fibrillation [PDF]

open access: yesJournal of Biological Physics 49 (2023) 521-533, 2023
Sustained spiral waves, also known as rotors, are pivotal mechanisms in persistent atrial fibrillation (AF). Stochasticity is inevitable in nonlinear biological systems such as the heart; however, it is unclear how noise affects the instability of spiral waves in human AF.
arxiv   +1 more source

Paraquat ingestion in an adult with cystic fibrosis (CF): Diagnostic and management dilemmas

open access: yesRespirology Case Reports, 2023
N,N'‐dimethyl‐4,4'bipyridinium dichloride (Paraquat) is a potent herbicide used widely in agriculture. We report the effects of an ingestion of paraquat by a 28 year old male with cystic fibrosis and the diagnostic and management challenges this posed in
Ieuan E. S. Evans   +8 more
doaj   +1 more source

Efficacy of the Simeox® Airway Clearance Technology in the Homecare Treatment of Children with Clinically Stable Cystic Fibrosis: A Randomized Controlled Trial

open access: yesChildren, 2023
Background: Cystic fibrosis (CF) patients require regular airway clearance therapy (ACT). The aim of this study was to evaluate homecare therapeutic effects of a new ACT (Simeox®) added to the optimal standard of care, including home chest physiotherapy,
Dorota Sands   +8 more
doaj   +1 more source

Recombinant truncated latency-associated peptide alleviates liver fibrosis in vitro and in vivo via inhibition of TGF-β/Smad pathway

open access: yesMolecular Medicine, 2022
Background Liver fibrosis is a progressive liver injury response. Transforming growth factor β1 (TGF-β1) is oversecreted during liver fibrosis and promotes the development of liver fibrosis.
Xudong Song   +10 more
doaj   +1 more source

Guía de Práctica Clínica para el manejo nutricional de personas con Fibrosis Quística (GPC-FQ)

open access: yesRevista Española de Nutrición Humana y Dietética, 2017
La fibrosis quística (FQ) es una enfermedad multiorgánica, hereditaria, autosómica y recesiva cuyos problemas más frecuentes están relacionados con las alteraciones de los pulmones y del páncreas exocrino.
María Garriga   +7 more
doaj   +1 more source

Malignancies in patients with cystic fibrosis: a case series

open access: yesJournal of Medical Case Reports, 2022
Background Previous reports have shown an increased number of colorectal cancers in patients with cystic fibrosis. We assessed the database of our cystic fibrosis center to identify patients with all kinds of cancer retrospectively. All patients visiting
Dorothea Appelt   +3 more
doaj   +1 more source

Influence of portal vein occlusion on portal flow and liver elasticity in an animal model [PDF]

open access: yesNMR in Biomedicine, Wiley, 2021, pp.e4498, 2021
Hepatic fibrosis causes an increase in liver stiffness, a parameter measured by elastography and widely used as a diagnosis method. The concomitant presence of portal vein thrombosis (PVT) implies a change in hepatic portal inflow that could also affect liver elasticity.
arxiv   +1 more source

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