Results 221 to 230 of about 1,332,119 (257)

Understanding cystic lung lesions in smokers with interstitial lung disease: radiologic-pathological correlation. [PDF]

Insights Imaging
Arenas-Jiménez JJ, Aranda I, Shalygina S, Alenda C, Ferrandez-Ferrandez D, García-Garrigós E.   +5 more
europepmc   +1 more source

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

Advanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang, Xinru Zhang, Baolong Wang, Haipeng Li, Dongshuo Xu, Yun Yang, Jialu Zhang, Wenbing Wang, Ren Zhang, Xinyu Wang, Yunfeng Cai, Shiyu Cao, Chao Hou, Changhui Wang   +13 more
wiley   +1 more source

Aspartate Aminotransferase to Platelet Ratio Index (APRI), Göteborg University Cirrhosis Index (GUCI), and Fibrosis 4 Score (FIB-4) proved to be the optimal biomarkers for the assessment of liver fibrosis in patients chronically infected with hepatitis C virus in Brazil. [PDF]

Rev Assoc Med Bras (1992)
Dantas BP, Magri MC, Manchiero C, Nunes AKDS, Prata TVG, Tengan FM.   +5 more
europepmc   +1 more source

Asprosin Aggravates Tubular Epithelial Cell Injury and Phenotypic Transformation via Mitochondrial Dynamics Disorder Mediated by Excessive Drp1 SUMOylation in Diabetic Nephropathy Mice

Advanced Science, EarlyView.
ASP aggravates TEC injury and phenotypic transformation via mitochondrial dynamics disorder mediated by excessive Drp1 SUMOylation in DKD mice. However, either ASP deficiency or AASP effectively alleviates the kidney injury and mitochondrial dynamics disorder induced by STZ/HFD, highlighting that ASP could be an early diagnostic marker and potential ...
Qianqian Huang, Xiaowei Xiong, Sheng Chen, Yuan Wang, Li Wang, Wentao Liu, Chen Liu, Guohua Zeng, Qiren Huang   +8 more
wiley   +1 more source

COVID-19 and chronic liver disease: results from the 1219 patients French registry. [PDF]

Sci Rep
Blaise L, Lebossé F, Costentin C, Ahmed SS, Heurgué A, Fontaine H, Meszaros M, Radenne S, Vanlemmens C, Landrieux A, Bouzbib C, Barraud H, Bardou-Jacquet E, Chazouillères O, Latournerie M, Rosa I, Anty R, Gelu-Simeon M, Khaldi M, Amaddeo G, Lemaitre C, Bernard-Chabert B, Moga L, Roulot-Marullo D, Elkrief L, Boursier J, Plessier A, Bureau C, Pageaux GP, Rémy AJ, Sultanik P, de Ledinghen V, Reboux N, Texier F, Hiriart JB, Montialoux H, de Montigny S, Rudler M, Williet N, Talib Z, Mboup B, Bourlière M, Vicaut E, Ganne-Carrié N, Dumortier J.   +44 more
europepmc   +1 more source

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Advanced Science, EarlyView.
This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang   +7 more
wiley   +1 more source

Hepatic ENTPD5 Is Critical for Maintaining Metabolic Homeostasis and Promoting Brown Adipose Tissue Thermogenesis

Advanced Science, EarlyView.
ENTPD5‐mediated conversion of extracellular adenosine triphosphate to ADP of hepatocytes is critical for maintaining hepatic glucose/lipid metabolism and promoting brown adipose tissue thermogenesis via the inhibition of adrenomedullin expression and secretion.
Rufeng Ma, Song Hou, Rui Xiang, Wenjun Liu, Xin Li, Yujing Chi, Ming Xu, Haochen Yao, Jing Li, Jichun Yang   +9 more
wiley   +1 more source

GLUT and FAPα as molecular markers for interstitial lung disease in systemic sclerosis. [PDF]

Respir Res
Broens B, van der Laken CJ, Radonic T, Nossent EJ, Manz XD, Mulder DJ, Al-Adwi Y, Gan CT, Timens W, Voskuyl AE, Duitman JW.   +10 more
europepmc   +1 more source

The role of CARMA3 in regulating fibrosis to prevent hypertrophic cardiomyopathy. [PDF]

Cell Death Discov
Liu Y, Chen G, Yao Y, Jiang Y, Wen C, Wang W, Liu Q, Cao Y, Huang F, Chen W, Qiu Z.   +10 more
europepmc   +1 more source