Results 221 to 230 of about 1,163,030 (369)

Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

open access: yesAdvanced Science, EarlyView.
By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan   +16 more
wiley   +1 more source

AI-Based Platelet-Independent Noninvasive Test for Liver Fibrosis in MASLD Patients. [PDF]

open access: yesJGH Open
Wakabayashi SI   +9 more
europepmc   +1 more source

Pulmonary Fibrosis in Workers Exposed to Finely Powdered Aluminium [PDF]

open access: bronze, 1961
John B. Mitchell   +3 more
openalex   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

open access: yesAdvanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang   +12 more
wiley   +1 more source

Cytomegalovirus-associated pulmonary exacerbation in patients with cystic fibrosis

open access: yesERJ Open Research, 2018
Akhil Sawant   +5 more
doaj   +1 more source

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