Results 81 to 90 of about 1,410,782 (208)

Lung function improvement on triple modulators: high-resolution, nationwide data from the Danish Cystic Fibrosis Cohort

ERJ Open Research
Background People living with cystic fibrosis in Denmark had early, universal access to triple modulator treatment with elexacaftor/tezacaftor/ivacaftor.
Christian Leo-Hansen, Daniel Faurholt-Jepsen, Tavs Qvist, Christine Højte, Bibi U. Nielsen, Thomas Bryrup, Esben H. Henriksen, Terese Katzenstein, Marianne Skov, Inger H.M. Mathiesen, Majbritt Jeppesen, Søren Jensen-Fangel, Hanne V. Olesen, Frederik Fouirnaies Buchvald, Kim Gjerum Nielsen, Espen Jimenez-Solem, Christian Ritz, Tacjana Pressler, Mette F. Olsen, the TransformCF Study Group   +19 more
doaj   +1 more source

Early life growth patterns persist for 12 years and impact pulmonary outcomes in cystic fibrosis [PDF]

, 2018
BACKGROUND: In children with cystic fibrosis (CF), recovery from growth faltering within 2 years of diagnosis (Responders) is associated with better growth and less lung disease at age 6 years.
Farrell, Philip M., Lai, HuiChuan J., Sanders, Don B., Zhang, Zhumin   +3 more
core   +1 more source

Televisit with TytoHome™ device in medically complex child in long-term mechanical ventilation: a pilot study

Italian Journal of Pediatrics
Background During the pandemic, the pneumology team at Bambino Gesù Children’s Hospital highlighted that telemedicine was a valuable tool for remotely managing the medical needs of children with medical complexity (CMC).
Alessandro Onofri, Nicola Ullmann, Elisabetta Verrillo, Maria Giovanna Paglietti, Martino Pavone, Renato Cutrera   +5 more
doaj   +1 more source

Physical activity and activity space in patients with pulmonary fibrosis not prescribed supplemental oxygen

BMC Pulmonary Medicine, 2017
Background Patients with pulmonary fibrosis (PF) have impaired quality of life, and research suggests that dyspnea and physical activity are primary drivers. As PF progresses, some patients notice the disease “shrinks their worlds”. The objective of this
Elisabeth Dowling Root, Bridget Graney, Susan Baird, Tara Churney, Kailtin Fier, Majorie Korn, Mark McCormic, David Sprunger, Tomas Vierzba, Frederick S. Wamboldt, Jeffery J. Swigris   +10 more
doaj   +1 more source

Biomarkers of Inflammation and Fibrosis in Kawasaki Disease Patients Years After Initial Presentation With Low Ejection Fraction. [PDF]

, 2020
Background Coronary artery aneurysms and myocarditis are well-recognized complications of Kawasaki disease (KD) but no systematic evaluation of the consequences of myocarditis has been performed in the subset presenting with low ejection fraction (EF ...
Burns, Jane C, He, Feng, Hoshino, Shinsuke, Jain, Sonia, Shimizu, Chisato, Tremoulet, Adriana H   +5 more
core  

The complexities of elexacaftor/tezacaftor/ivacaftor therapeutic drug monitoring in a person with cystic fibrosis and Mycobacterium abscessus pulmonary disease

European Clinical Respiratory Journal
Therapeutic drug monitoring (TDM) of elexacaftor/tezacaftor/ivacaftor (ETI) remains challenging due to a lack of clarity around the parameters that govern ETI plasma concentrations, whilst the use of concomitant CYP3A inducers rifabutin and rifampicin is
Claire Y Mou, Daniel J Henderson, Angela G Matson, Karen M Herd, David W Reid, Timothy Riddles, Ellie Johnson, Brett McWhinney, Rebecca Swenson, Andrew Burke, Ieuan E S Evans   +10 more
doaj   +1 more source

Diagnostic value of two dimensional shear wave elastography combined with texture analysis in early liver fibrosis. [PDF]

, 2019
BACKGROUND: Staging diagnosis of liver fibrosis is a prerequisite for timely diagnosis and therapy in patients with chronic hepatitis B. In recent years, ultrasound elastography has become an important method for clinical noninvasive assessment of liver ...
Hu, Xiang-Dong, Jian, Zhao-Cheng, Li, Wei-Sheng, Liu, Ji-Bin, Liu, Yu-Jiang, Long, Jin-Feng, Qian, Lin-Xue, Shi, Xian-Quan   +7 more
core   +1 more source

Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor

Nature Communications, 2017
Asthma is characterized by abnormal airway hyperresponsiveness. Here the authors identify BPIFA1 as a factor secreted by airway epithelial cells, and show that it regulates contractility of airway smooth muscle cells by binding to and regulating the ...
Tongde Wu, Julianne Huang, Patrick J. Moore, Michael S. Little, William G. Walton, Robert C. Fellner, Neil E. Alexis, Y. Peter Di, Matthew R. Redinbo, Stephen L. Tilley, Robert Tarran   +10 more
doaj   +1 more source

Keratin variants associate with progression of fibrosis during chronic hepatitis C infection† [PDF]

, 2006
Pavel Strnad, Tim C. Lienau, Guo‐Zhong Tao, Laura C. Lazzeroni, Felix Stickel, Detlef Schuppan, M. Bishr Omary   +6 more
openalex   +1 more source

Genetic Modifying Factors of Cystic Fibrosis Phenotype: A Challenge for Modern Medicine [PDF]

, 2021
Lăcrămioara Ionela Butnariu, Elena Ţarcă, Elena Cojocaru, Cristina Rusu, Ștefana Maria Moisă, Maria Magdalena Leon, Eusebiu Vlad Gorduza, Laura Mihaela Trandafir   +7 more
openalex   +1 more source