Results 61 to 70 of about 833,135 (278)

Constraining conformal field theories with a slightly broken higher spin symmetry

, 2012
We consider three dimensional conformal field theories that have a higher spin symmetry that is slightly broken. The theories have a large N limit, in the sense that the operators separate into single trace and multitrace and obey the usual large N ...
Aharony O Gur-Ari G Yacoby R, Alexander Zhiboedov, Anninos D Hartman T Strominger A, Anselmi D, Bianchi M, Chang C-M Yin X, Chang C-M Yin X, Costa M S Penedones J Poland D Rychkov S, Gaberdiel M R, Gaberdiel M R, Giombi S, Giombi S, Giombi S Minwalla S Prakash S Trivedi S P Wadia S R Yin X, Giombi S Prakash S Yin X, Giombi S Yin X, Hertog T, Juan Maldacena, Maldacena J M, Maldacena J Zhiboedov A, Mikhailov A, Moore G W, Ng G S Strominger A, Ruhl W, Sagnotti A, Sezgin E, Vasiliev M A, Vasiliev M A, Witten E   +27 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Spinors fields in co-dimension one braneworlds

Journal of High Energy Physics, 2018
In this work we analyze the zero mode localization and resonances of 1/2−spin fermions in co-dimension one Randall-Sundrum braneworld scenarios. We consider delta-like, domain walls and deformed domain walls membranes.
W.M. Mendes, G. Alencar, R.R. Landim
doaj   +1 more source

T T ¯ $$ T\overline{T} $$ deformations in curved space from 4D Chern-Simons theory

Journal of High Energy Physics, 2022
In this paper, we shed new light onto T T ¯ $$ T\overline{T} $$ -deformations by engineering them on 2D surface defects, supporting chiral and antichiral CFT’s, in a 4D Chern-Simons bulk. This approach is motivated by various connections between T T ¯ $$
Victor Py
doaj   +1 more source

On the c-theorem in more than two dimensions [PDF]

, 2000
Several pieces of evidence have been recently brought up in favour of the c-theorem in four and higher dimensions, but a solid proof is still lacking.
Cappelli, A., D'Appollonio, G., Guida, R., Magnoli, N.   +3 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Localization of U(1) gauge vector field on flat branes with five-dimension (asymptotic) AdS5 spacetime

Journal of High Energy Physics, 2018
In order to localize U(1) gauge vector field on Randall-Sundrum-like braneworld model with infinite extra dimension, we propose a new kind of non-minimal coupling between the U(1) gauge field and the gravity.
Zhen-Hua Zhao, Qun-Ying Xie
doaj   +1 more source

Lightcone bootstrap at higher points

Journal of High Energy Physics, 2022
Higher-point functions of scalar operators are a rich observable in CFTs, as they contain OPE data involving multiple spinning operators. We derive the lightcone blocks for five- and six-point functions in the snowflake channel and use them to bootstrap ...
António Antunes, Miguel S. Costa, Vasco Gonçalves, João Vilas Boas   +3 more
doaj   +1 more source

The Analytic Bootstrap in Fermionic CFTs

, 2017
We apply the method of the large spin bootstrap to analyse fermionic conformal field theories with weakly broken higher spin symmetry. Through the study of correlators of composite operators, we find the anomalous dimensions and OPE coefficients in the ...
van Loon, Mark
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source