Results 81 to 90 of about 810,966 (282)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Rate of cluster decomposition via Fermat-Steiner point

Journal of High Energy Physics, 2019
In quantum field theory with a mass gap correlation function between two spatially separated operators decays exponentially with the distance. This fundamental result immediately implies an exponential suppression of all higher point correlation ...
Alexander Avdoshkin, Lev Astrakhantsev, Anatoly Dymarsky, Michael Smolkin   +3 more
doaj   +1 more source

Topological dualities in the Ising model [PDF]

, 2018
We relate two classical dualities in low-dimensional quantum field theory: Kramers-Wannier duality of the Ising and related lattice models in $2$ dimensions, with electromagnetic duality for finite gauge theories in $3$ dimensions.
Freed, Daniel S, Teleman, Constantin
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

O(N) and O(N) and O(N)

, 2017
Three related analyses of $\phi^4$ theory with $O(N)$ symmetry are presented. In the first, we review the $O(N)$ model over the $p$-adic numbers and the discrete renormalization group transformations which can be understood as spin blocking in an ...
Gubser, Steven S., Jepsen, Christian, Parikh, Sarthak, Trundy, Brian   +3 more
core   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

A Rényi quantum null energy condition: proof for free field theories

Journal of High Energy Physics, 2021
The Quantum Null Energy Condition (QNEC) is a lower bound on the stress-energy tensor in quantum field theory that has been proved quite generally.
Mudassir Moosa, Pratik Rath, Vincent Paul Su   +2 more
doaj   +1 more source

The Exact Renormalization Group and Higher-spin Holography

, 2014
In this paper, we revisit scalar field theories in $d$ space-time dimensions possessing $U(N)$ global symmetry. Following our recent work arXiv:1402.1430v2, we consider the generating function of correlation functions of all $U(N)$-invariant, single ...
Leigh, Robert G., Parrikar, Onkar, Weiss, Alexander B.   +2 more
core   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source