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Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities
Atopic dermatitis (AtD) is multifactorial inflammatory skin disease, one of the aspects of its pathogenesis is epidermal barrier dysfunction. Early development of AtD is associated with filaggrin dysfunction.
Nikolay N. Murashkin+6 more
doaj +1 more source
Comparative immune responses against Psoroptes ovis in two cattle breeds with different susceptibility to mange [PDF]
The sheep scab mite, Psoroptes ovis, is a major problem in the beef cattle industry, especially in Belgian Blue (BB) cattle. This breed is naturally more predisposed to psoroptic mange but reasons for this high susceptibility remain unknown.
Chiers, Koen+9 more
core +4 more sources
The Pathogenesis of Atopic Dermatitis: The Role of Filaggrin
Background: Atopic dermatitis (AD) is a multifactorial skin disease with waxing and waning inflammatory process. In recent years, genetic mutations namely the null mutations of the filaggrin gene (FLG) has been the focus in AD risk factors investigations.
Tamarachiara Kuntjoro, Erna Harijati
doaj +1 more source
Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]
Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos+9 more
core +3 more sources
Dupilumab Significantly Reduces Symptoms of Prurigo Nodularis and Depression: A Case Series
is missing (Short communication)
Louise Lönndahl+3 more
doaj +1 more source
Profile of clindamycin phosphate 1.2%/benzoyl peroxide 3.75% aqueous gel for the treatment of acne vulgaris. [PDF]
Acne vulgaris is a common and chronic skin disease, and is a frequent source of morbidity for affected patients. Treatment of acne vulgaris is often difficult due to the multifactorial nature of this disease.
Eichenfield, Lawrence F, Nguyen, Tuyet A
core +2 more sources
Background Filaggrin proteins are located in the skin and prevent epidermal water loss and impede the entry of micro-organisms, allergens and chemicals.
Allan Linneberg+11 more
doaj +1 more source
Edible bird’s nest (EBN) is a Chinese delicacy possessing skin rejuvenating functions. To verify skin anti-inflammatory function of EBN, water extract and enzymatic digest of EBN, as well as the major sialic acid, N-acetyl neuraminic acid (NANA), were ...
Queenie Wing Sze Lai+10 more
doaj +1 more source
A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. [PDF]
Keratin intermediate filaments (KIFs) protect the epidermis against mechanical force, support strong adhesion, help barrier formation, and regulate growth.
Adams+140 more
core +1 more source
Fleshing Out Filaggrin Phenotypes [PDF]
The association of filaggrin null alleles with eczema has been replicated in several European populations. Three large, well-conducted studies confirm this association and offer insights into the phenotypic nature of eczema associated with these alleles.
Alan D. Irvine, Alan D. Irvine
openaire +3 more sources