Results 51 to 60 of about 17,224 (237)

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Goras Georgios, Thrasyvoulou Andreas, Tsilimpokou Evanthia   +2 more
wiley   +1 more source

Fleshing Out Filaggrin Phenotypes [PDF]

Journal of Investigative Dermatology, 2007
The association of filaggrin null alleles with eczema has been replicated in several European populations. Three large, well-conducted studies confirm this association and offer insights into the phenotypic nature of eczema associated with these alleles.
openaire   +2 more sources

Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s):Several investigations have revealed that caspase-14 is responsible for the epidermal differentiation and cornification, as well as the regulation of moisturizing effect. However, the precise regulation mechanism is still not clear.
Ningning Dang, Shuguang Pang, Haiyan Song, Liguo An, Xiaoli Ma   +4 more
doaj  

Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment [PDF]

, 2017
Filaggrin (FLG) mutations are a strong risk factor to develop atopic dermatitis (AD). However, the relationship between FLG mutations and treatment outcome in AD has not been thoroughly studied.
Bos, J. D., Campbell, L. E., Irwin McLean, W. H., Kezic, S., Leeflang, M. M. G., Middelkamp-Hup, M. A., Roekevisch, E., Schram, M. E., Spuls, P. I.   +8 more
core   +2 more sources

Evaluation of OVOL1 and Filaggrin immunohistochemical expression and clinical relevance in psoriasis

Diagnostic Pathology
Background Psoriasis is a disease of overactive immune system. OVOL1 and Filaggrin have been associated with many inflammatory skin lesions. To the best of our knowledge, the correlation between OVOL1 and Filaggrin in psoriasis was not previously ...
Aiat Shaban Hemida, Mostafa Ahmed Hammam, Aya Ahmed Swilam, Wafaa Ahmed Shehata   +3 more
doaj   +1 more source

Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses:part II of a prospective cohort study [PDF]

, 2013
BACKGROUND/OBJECTIVES: Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet ...
Bakker, Jan G., Bos, Jan D., Calkoen, Florentine, Campbell, Linda E., Kezic, Sanja, McLean, W. H. Irwin, Van Dijk, Frank J. H., Verberk, Maarten M., Visser, Maaike J.   +8 more
core   +2 more sources

Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]

, 2020
Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos, Baldrich, Esther Serra, Herráez, L., Jáuregui, Ignacio, Martín-Santiago, Ana, Ortiz de Frutos, Javier, Sastre, Joaquin, Silvestre, Juan Francisco, Universitat Autònoma de Barcelona, Valero, Antonio   +9 more
core   +3 more sources

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes

Scientific Reports, 2017
GATA3 is a transcription factor with an important role in atopic diseases because of its role in the differentiation of Th2 lymphocytes. Moreover, GATA3 is expressed in keratinocytes and has a role in keratinocyte differentiation and the establishment of
Jana Zeitvogel, Neele Jokmin, Samira Rieker, Ilona Klug, Christina Brandenberger, Thomas Werfel   +5 more
doaj   +1 more source