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A new neuronal intermediate filament protein
Trends in Neurosciences, 1989It would be an understatement to say that the vertebrate nervous system appears complex. The characterization and classification of its components rely, in addition to its gross anatomy, on analyses of the differential expression of cytoskeletal and other cellular structures and products.
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Molecular Phylogeny of Metazoan Intermediate Filament Proteins
Journal of Molecular Evolution, 1998We have cloned cytoplasmic intermediate filament (IF) proteins from a large number of invertebrate phyla using cDNA probes, the monoclonal antibody IFA, peptide sequence information, and various RT-PCR procedures. Novel IF protein sequences reported here include the urochordata and nine protostomic phyla, i.e., Annelida, Brachiopoda, Chaetognatha ...
Erber, A. +3 more
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Intermediate filament proteins in echinoderm coelomocytes
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2000The presence and organization of intermediate filament (IF) proteins in petaloid coelomocytes from two species of echinoderms, the sea urchin Strongylocentrotus droehachiensis and the sea cucumber Cucumaria frondosa, were studied. Two monoclonal antibodies (IFA and Ah6) and one polyclonal antibody (W3-1) that together recognize invertebrate as well as ...
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Intermediate filament proteins participate in signal transduction
Trends in Cell Biology, 2005How timely transport of chemical signals between the distal end of long axonal processes and the cell bodies of neurons occurs is an interesting and unresolved issue. Recently, Perlson et al. presented evidence that cleavage products of newly synthesized vimentin, an intermediate filament (IF) protein, interact with mitogen-activated protein (MAP ...
Brian T, Helfand +3 more
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Interactions of intermediate filament proteins from wool
International Journal of Biological Macromolecules, 1991Filaments of wool are heteropolymers formed by interaction of type I and type II intermediate filament (IF) proteins. There are four proteins in each of these two classes. Interaction of the reduced wool IF proteins was studied by two-dimensional electrophoresis which showed that complexes between type I and type II proteins were formed in solution at ...
J, Herrling, L G, Sparrow
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[Neuronal intermediate filament proteins].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1997The characteristics of the seven intermediate filament proteins expressed during the development of neurons are reviewed. The most extensively studied have been neurofilament proteins (NFP) and peripherin. The relative plasticity of the peripherin network can account for its possible role during development when the axons of the neurons in which this ...
O, Bousquet, M M, Portier
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Intermediate filament proteins in developing human arteries
Anatomy and Embryology, 1999The distribution of intermediate filament proteins in adult human blood vessels and in human fetal elastic arteries is relatively well-known. However, the distribution of these proteins in the course from neonate to adult has not been established. In this investigation, human postnatal arteries were studied with immunohistochemistry, using antibodies ...
B, Johansson, A, Eriksson, L E, Thornell
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Intermediate Filament Proteins and Their Associated Diseases
New England Journal of Medicine, 2004Intermediate filaments provide scaffolding for the cell and protect it against stress. This comprehensive review points out that there are more than 100 intermediate filament genes and that mutant intermediate filament proteins cause more than 30 diseases.
M Bishr, Omary +2 more
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Antibodies to Intermediate Filament Proteins
Archives of Dermatology, 1985One hundred cutaneous tumors were investigated immunohistopathologically for the expression of intermediate filament (IF) proteins. Epithelial tumors, such as basocellular and squamous cell carcinomas, cutaneous adnexal tumors, and metastatic carcinomas showed keratin positivity in a varying number of tumor cells with two keratin antibodies with ...
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The Molecular Biology of Intermediate Filament Proteins
1992Publisher Summary This chapter focuses on intermediate-filament (IF)-protein family and describes the role intermediate filaments play within cells and tissues. IFs are composed of proteins that self-assemble into filaments that form complex cytoskeletal networks. These proteins are highly diverse and exhibit cell-type specificity of expression.
K, Albers, E, Fuchs
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