Results 31 to 40 of about 105,051 (306)

Intermediate Filaments and Polarization in the Intestinal Epithelium

open access: yesCells, 2016
The cytoplasmic intermediate filament cytoskeleton provides a tissue-specific three-dimensional scaffolding with unique context-dependent organizational features.
Richard A. Coch, Rudolf E. Leube
doaj   +1 more source

Desmin Reorganization by Stimuli Inducing Oxidative Stress and Electrophiles: Role of Its Single Cysteine Residue

open access: yesAntioxidants, 2023
The type III intermediate filament proteins vimentin and GFAP are modulated by oxidants and electrophiles, mainly through perturbation of their single cysteine residues.
Diego Moneo-Corcuera   +3 more
doaj   +1 more source

Epithelial Intermediate Filaments: Guardians against Microbial Infection?

open access: yesCells, 2016
Intermediate filaments are abundant cytoskeletal components of epithelial tissues. They have been implicated in overall stress protection. A hitherto poorly investigated area of research is the function of intermediate filaments as a barrier to microbial
Florian Geisler, Rudolf E. Leube
doaj   +1 more source

BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways

open access: yesFrontiers in Pharmacology, 2023
Introduction: Diabetic nephropathy (DN), a chronic kidney disease, is a major cause of end-stage kidney disease worldwide. Mesenchymal stem cells (MSCs) have become a promising option to mitigate several diabetic complications.Methods: In this study, we ...
Tarek Khamis   +33 more
doaj   +1 more source

Role of the gp85/trans-sialidases in Trypanosoma cruzi tissue tropism: preferential binding of a conserved peptide motif to the vasculature in vivo. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
BACKGROUND: Transmitted by blood-sucking insects, the unicellular parasite Trypanosoma cruzi is the causative agent of Chagas' disease, a malady manifested in a variety of symptoms from heart disease to digestive and urinary tract dysfunctions.
Renata R Tonelli   +9 more
doaj   +1 more source

Role of Intermediate Filaments in Blood–Brain Barrier in Health and Disease

open access: yesCells, 2021
The blood–brain barrier (BBB) is a highly selective cellular monolayer unique to the microvasculature of the central nervous system (CNS), and it mediates the communication of the CNS with the rest of the body by regulating the passage of molecules into ...
Ece Bayir, Aylin Sendemir
doaj   +1 more source

Homologous Recombination under the Single-Molecule Fluorescence Microscope [PDF]

open access: yes, 2019
Homologous recombination (HR) is a complex biological process and is central to meiosis and for repair of DNA double-strand breaks. Although the HR process has been the subject of intensive study for more than three decades, the complex protein–protein ...
Dhakal, Soma, Gibbs, Dalton R.
core   +2 more sources

Immunohistochemical expression of intermediate filaments in diagnostics of diffuse gliomas.

open access: yesMedičnì Perspektivi, 2017
Intermediate filament proteins play an important role in maintaining a stable shape, as well as the possible movement of cells, including neoplastic cells.
T. V. Shynkarenko
doaj   +1 more source

Keratin 76 is required for tight junction function and maintenance of the skin barrier. [PDF]

open access: yesPLoS Genetics, 2014
Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice.
Tia DiTommaso   +6 more
doaj   +1 more source

Vimentin filaments are assembled from a soluble precursor in avian erythroid cells [PDF]

open access: yes, 1983
The synthesis and assembly of vimentin was studied in erythroid cells from 10-d-old chicken embryos. After various periods of [35S]methionine incorporation, cells were lysed in a Triton X-100-containing buffer and separated into a soluble and an ...
Blikstad, Ingrid, Lazarides, Elias
core   +3 more sources

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