Results 21 to 30 of about 105,051 (306)

Contrasting expression of keratins in mouse and human embryonic stem cells. [PDF]

PLoS ONE, 2008
RNA expression data reveals that human embryonic stem (hES) cells differ from mouse ES (mES) cells in the expression of RNAs for keratin intermediate filament proteins.
Jochen Maurer, Brandon Nelson, Grace Ceceña, Ruchi Bajpai, Mark Mercola, Alexey Terskikh, Robert G Oshima   +6 more
doaj   +1 more source

Deimination, Intermediate Filaments and Associated Proteins [PDF]

International Journal of Molecular Sciences, 2020
Deimination (or citrullination) is a post-translational modification catalyzed by a calcium-dependent enzyme family of five peptidylarginine deiminases (PADs). Deimination is involved in physiological processes (cell differentiation, embryogenesis, innate and adaptive immunity, etc.) and in autoimmune diseases (rheumatoid arthritis, multiple sclerosis ...
Briot, Julie, Simon, Michel, Méchin, Marie-Claire   +2 more
openaire   +2 more sources

Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly. [PDF]

PLoS ONE, 2015
Keratins are cytoskeletal proteins that hierarchically arrange into filaments, starting with the dimer sub-unit. They are integral to the structural support of cells, in skin, hair and nails.
David J Bray, Tiffany R Walsh, Massimo G Noro, Rebecca Notman   +3 more
doaj   +1 more source

Intermediate Filament Protein Partnership in Astrocytes [PDF]

Journal of Biological Chemistry, 1999
Intermediate filaments are general constituents of the cytoskeleton. The function of these structures and the requirement for different types of intermediate filament proteins by individual cells are only partly understood. Here we have addressed the role of specific intermediate filament protein partnerships in the formation of intermediate filaments ...
C, Eliasson, C, Sahlgren, C H, Berthold, J, Stakeberg, J E, Celis, C, Betsholtz, J E, Eriksson, M, Pekny   +7 more
openaire   +2 more sources

Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers

Nature Communications, 2023
Toxic protein aggregates can spread among neurons to promote human neurodegenerative disease pathology. We found that in C. elegans touch neurons intermediate filament proteins IFD-1 and IFD-2 associate with aggresome-like organelles and are required ...
Meghan Lee Arnold, Jason Cooper, Rebecca Androwski, Sohil Ardeshna, Ilija Melentijevic, Joelle Smart, Ryan J. Guasp, Ken C. Q. Nguyen, Ge Bai, David H. Hall, Barth D. Grant, Monica Driscoll   +11 more
doaj   +1 more source

Neurofilament Light Chain (NfL) in Blood—A Biomarker Predicting Unfavourable Outcome in the Acute Phase and Improvement in the Late Phase after Stroke

Cells, 2021
Increased sensitivity of methods assessing the levels of neurofilament light chain (NfL), a neuron-specific intermediate filament protein, in human plasma or serum, has in recent years led to a number of studies addressing the utility of monitoring NfL ...
Milos Pekny, Ulrika Wilhelmsson, Anna Stokowska, Turgut Tatlisumak, Katarina Jood, Marcela Pekna   +5 more
doaj   +1 more source

Molecular evolution of type VI intermediate filament proteins

BMC Evolutionary Biology, 2007
Background Tanabin, transitin and nestin are type VI intermediate filament (IF) proteins that are developmentally regulated in frogs, birds and mammals, respectively.
Vincent Michel, Savard Pierre E, Khan Paul A, Guérette Dominique   +3 more
doaj   +1 more source

Isolation of a new high molecular weight protein associated with desmin and vimentin filaments from avian embryonic skeletal muscle [PDF]

, 1982
Filaments with a diameter of 80-120 Å have been prepared from 14-d-old chick embryonic skeletal muscle, using a physiological salt solution and gel filtration chromatography.
Breckler, Jennifer, Lazarides, Elias
core   +2 more sources

Role of Intermediate Filaments in Vesicular Traffic

Cells, 2016
Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells.
Azzurra Margiotta, Cecilia Bucci
doaj   +1 more source

Intrinsic structural disorder in cytoskeletal proteins. [PDF]

, 2013
Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and ...
Beata Szabo, Mainak Guharoy, Peter Tompa, Sara Contreras Martos, Simone Kosol   +4 more
core   +1 more source