Trypanosoma cruzi Binds to Cytokeratin through Conserved Peptide Motifs Found in the Laminin-G-Like Domain of the gp85/Trans-sialidase Proteins. [PDF]
PLoS Neglected Tropical Diseases, 2015 BACKGROUND:Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, is a disease that affects millions of people most of them living in South and Central Americas. There are few treatment options for individuals with Chagas' disease making it
Andre Azevedo Reis Teixeira +4 more
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Expression of oestrogen and progesterone receptor and intermediate filament proteins in the oviduct of mares with endometrosis [PDF]
Animal Science and Genetics, 2023 Equine endometrosis is one of the major causes of equine infertility, often associated with signs of periglandular fibrosis occurring in the endometrium.
Magdalena Profaska +5 more
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Contrasting expression of keratins in mouse and human embryonic stem cells. [PDF]
PLoS ONE, 2008 RNA expression data reveals that human embryonic stem (hES) cells differ from mouse ES (mES) cells in the expression of RNAs for keratin intermediate filament proteins.
Jochen Maurer +6 more
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Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly. [PDF]
PLoS ONE, 2015 Keratins are cytoskeletal proteins that hierarchically arrange into filaments, starting with the dimer sub-unit. They are integral to the structural support of cells, in skin, hair and nails.
David J Bray +3 more
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Deimination, Intermediate Filaments and Associated Proteins [PDF]
International Journal of Molecular Sciences, 2020 Deimination (or citrullination) is a post-translational modification catalyzed by a calcium-dependent enzyme family of five peptidylarginine deiminases (PADs). Deimination is involved in physiological processes (cell differentiation, embryogenesis, innate and adaptive immunity, etc.) and in autoimmune diseases (rheumatoid arthritis, multiple sclerosis ...
Briot, Julie +2 more
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Nature Communications, 2023 Toxic protein aggregates can spread among neurons to promote human neurodegenerative disease pathology. We found that in C. elegans touch neurons intermediate filament proteins IFD-1 and IFD-2 associate with aggresome-like organelles and are required ...
Meghan Lee Arnold +11 more
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Cells, 2021 Increased sensitivity of methods assessing the levels of neurofilament light chain (NfL), a neuron-specific intermediate filament protein, in human plasma or serum, has in recent years led to a number of studies addressing the utility of monitoring NfL ...
Milos Pekny +5 more
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Molecular evolution of type VI intermediate filament proteins
BMC Evolutionary Biology, 2007 Background Tanabin, transitin and nestin are type VI intermediate filament (IF) proteins that are developmentally regulated in frogs, birds and mammals, respectively.
Vincent Michel +3 more
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Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization [PDF]
, 2001 The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines the inner nuclear membrane. The lamina is proposed to be an important determinant of nuclear structure, but there has been little direct testing of this idea.
Tinglu Guan +5 more
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Role of Intermediate Filaments in Vesicular Traffic
Cells, 2016 Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells.
Azzurra Margiotta, Cecilia Bucci
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