Results 41 to 50 of about 105,051 (306)

Nonlinear Elasticity in Biological Gels [PDF]

, 2004
Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the molecular ...
AD Karakaplan, AY Grosberg, Cornelis Storm, D Morse, DA Head, F Gittes, F Gittes, F MacKintosh, F. C. MacKintosh, J Marko, J Wilhelm, J Wilhelm, J Xu, Jennifer J. Pastore, JF Leterrier, JO Hjortdal, JV Shah, K Kroy, L Ma, LD Landau, LD Landau, LRG Treloar, LZ Wang, M Fixman, ML Gardel, PA Janmey, PA Janmey, PA Janmey, PA Janmey, Paul A. Janmey, RE Shadwick, SB Smith, T. C. Lubensky, Y Fung   +33 more
core   +2 more sources

Intermediate filament-co-localized molecules with myosin heavy chain epitopes define distinct cellular domains in hair follicles and epidermis

BMC Cell Biology, 2003
Background Proteins linking intermediate filaments to other cytoskeletal components have important functions in maintaining tissue integrity and cell shape.
Hughes Simon M, Ehler Elisabeth, Jazwinska Ania   +2 more
doaj   +1 more source

Compare and contrast the reaction coordinate diagrams for chemical reactions and cytoskeletal force generators. [PDF]

, 2013
Reaction coordinate diagrams are used to relate the free energy changes that occur during the progress of chemical processes to the rate and equilibrium constants of the process.
Scholey, Jonathan M
core   +2 more sources

Trichinella britovi muscle larvae and adult worms: stage-specific and common antigens detected by two-dimensional gel electrophoresis-based immunoblotting

Parasites & Vectors, 2018
Background Trichinella britovi is the second most common species of Trichinella that may affect human health. As an early diagnosis of trichinellosis is crucial for effective treatment, it is important to identify sensitive, specific and common antigens ...
Sylwia Grzelak, Bożena Moskwa, Justyna Bień   +2 more
doaj   +1 more source

Assembly mechanisms of the bacterial cytoskeletal protein FilP

Life Science Alliance, 2019
FilP is a coiled-coil protein that self-assembles into striated filaments and meshwork that shares structural and biochemical characteristics with metazoan intermediate filaments. Despite low-sequence homology, the intermediate filament (IF)–like protein
Ala Javadi, Niklas Söderholm, Annelie Olofsson, Klas Flärdh, Linda Sandblad   +4 more
doaj   +1 more source

Role of beta1-adrenergic Blockade in Alleviation of Clozapine-induced Cardiotoxic effect in rats via modulation of cardiac cell death, macrophages, and gap junction intercellular communication proteins

SVU - International Journal of Medical Sciences
Background: Clozapine (CLZ) is an effective choice for the treatment of resistant schizophrenia; however, there is a risk of clozapine-induced cardiotoxicity.
Hala M ElBadre, Manal M Kamal* , Basel A Abdel-Wahab , et all.   +3 more
doaj   +1 more source

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells [PDF]

, 2016
Background: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for ...
Davis, John S., Hou, Xiaoying, Schwab, Nicolette M., Townson, David H., Trisdale, Sarah K.   +4 more
core   +3 more sources

Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens. [PDF]

PLoS ONE, 2012
The basis for mammalian lens fiber cell organization, transparency, and biomechanical properties has contributions from two specialized cytoskeletal systems: the spectrin-actin membrane skeleton and beaded filament cytoskeleton.
David S Gokhin, Roberta B Nowak, Nancy E Kim, Ernest E Arnett, Albert C Chen, Robert L Sah, John I Clark, Velia M Fowler   +7 more
doaj   +1 more source

Rapid transport of neural intermediate filament protein [PDF]

Journal of Cell Science, 2003
Peripherin is a neural intermediate filament protein that is expressed in peripheral and enteric neurons, as well as in PC12 cells. A determination of the motile properties of peripherin has been undertaken in PC12 cells during different stages of neurite outgrowth.
Brian T, Helfand, Patty, Loomis, Miri, Yoon, Robert D, Goldman   +3 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source