Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]
Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation.
Erich A. Nigg +19 more
core +1 more source
Structure of the hDmc1-ssDNA filament reveals the principles of its architecture [PDF]
In eukaryotes, meiotic recombination is a major source of genetic diversity, but its defects in humans lead to abnormalities such as Down's, Klinefelter's and other syndromes.
Dmitry V Bugreev +23 more
core +2 more sources
Immunohistochemical expression of intermediate filaments in diagnostics of diffuse gliomas.
Intermediate filament proteins play an important role in maintaining a stable shape, as well as the possible movement of cells, including neoplastic cells.
T. V. Shynkarenko
doaj +1 more source
Role of Intermediate Filaments in Blood–Brain Barrier in Health and Disease
The blood–brain barrier (BBB) is a highly selective cellular monolayer unique to the microvasculature of the central nervous system (CNS), and it mediates the communication of the CNS with the rest of the body by regulating the passage of molecules into ...
Ece Bayir, Aylin Sendemir
doaj +1 more source
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Christiana Ruhrberg +7 more
core +1 more source
Keratin 76 is required for tight junction function and maintenance of the skin barrier. [PDF]
Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice.
Tia DiTommaso +6 more
doaj +1 more source
Background Proteins linking intermediate filaments to other cytoskeletal components have important functions in maintaining tissue integrity and cell shape.
Hughes Simon M +2 more
doaj +1 more source
Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin [PDF]
The cornified envelope is a layer of transglutaminase cross-linked protein that is deposited under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Dooley, TP +9 more
core +1 more source
The apical submembrane cytoskeleton participates in the organization of the apical pole in epithelial cells [PDF]
In a previous publication (Rodriguez, M.L., M. Brignoni, and P.J.I. Salas. 1994. J. Cell Sci. 107: 3145-3151), we described the existence of a terminal web-like structure in nonbrush border cells, which comprises a specifically apical cytokeratin ...
Ana L. Viciana +14 more
core +1 more source
Background Trichinella britovi is the second most common species of Trichinella that may affect human health. As an early diagnosis of trichinellosis is crucial for effective treatment, it is important to identify sensitive, specific and common antigens ...
Sylwia Grzelak +2 more
doaj +1 more source

