Results 61 to 70 of about 21,702 (299)
BMC Research Notes, 2011 Background Canine atopic dermatitis (AD) is a common inflammatory skin disease associated with defects in the epidermal barrier, particularly in West Highland white terriers (WHWTs).
Roque Joana +4 more
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Frontiers in Molecular Biosciences, 2023 Atopic dermatitis (AD) is a common, chronic and relapsing inflammatory skin disease with various clinical presentations and combinations of symptoms. The pathophysiology of AD is complex and multifactorial.
Tubanur Çetinarslan +2 more
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GP37 Is Different From Filaggrin
Journal of Investigative Dermatology, 1990 The identity of two differentiation markers of human epidermis, filaggrin and a Concanavalin A (Con-A) reactive glycoprotein of 37 kD, has been studied. Human epidermis was extracted in Nonidet P-40 buffer, and the soluble proteins were separated by two-dimensional electrophoresis.
Alain Reano, Jean Thivolet, Yves Sarret
openaire +3 more sources
PLoS ONE, 2009 BackgroundFilaggrin is a major protein in the epidermis. Several mutations in the filaggrin gene (FLG) have been associated with a number of conditions.
Santiago Rodriguez +8 more
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Role of FGFR2b expression and signaling in keratinocyte differentiation. Sequential involvement of PKCδ and PKCα [PDF]
, 2018 The tumor suppressor epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) induces human keratinocyte early differentiation. Moreover, protein kinases C (PKCs) are known to regulate the differentiation program in several cellular ...
Belleudi, Francesca +4 more
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Male genital lichen sclerosus and filaggrin [PDF]
Clinical and Experimental Dermatology, 2019 Lichen sclerosus (LSc) is an acquired cutaneous disease of contentious aetiology. The majority of male cases involve the genitalia. Amongst prior postulated pathogenic factors in genital (G)LSc are infection, autoimmunity and genetic and environmental influences.1 There is an arguement that male (M)GLSc might be due to chronic occluded exposure of ...
T. N. Shim +8 more
openaire +3 more sources
Frontiers in Molecular Biosciences, 2023 Background: Loss of function mutation in FLG is the major genetic risk factor for atopic dermatitis (AD) and other allergic manifestations. Presently, little is known about the cellular turnover and stability of profilaggrin, the protein encoded by FLG ...
Argho Aninda Paul +5 more
doaj +1 more source
Association of Filaggrin Loss-of-Function Variants With Race in Children With Atopic Dermatitis.
JAMA dermatology, 2019 Importance Atopic dermatitis (AD) is a common chronic illness that has been associated with variation in the filaggrin gene (FLG). Four variants are most often evaluated.
D. Margolis +7 more
semanticscholar +1 more source
Advanced Materials, EarlyView.In this study, a vaginal specific ECM hydrogel (vECM) is developed, optimized for intravaginal topical administration, and evaluated for mitigatation of vaginal atrophy associated with menopause. When applied in a rat model of menopause, vECM improves vaginal epithelial thickness and stem cell phenotype, and despite topical application, vECM also ...
Emma I. Zelus +6 more
wiley +1 more source
Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s):Several investigations have revealed that caspase-14 is responsible for the epidermal differentiation and cornification, as well as the regulation of moisturizing effect. However, the precise regulation mechanism is still not clear.
Ningning Dang +4 more
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