Results 71 to 80 of about 18,701 (299)

Cranberry constituents prevent SOS-mediated filamentation of uropathogenic Escherichia coli

Infection and Immunity
The diameter, length, and shape of bacteria are maintained with such high fidelity that these parameters are classically used as metrics in the distinction of bacterial species.
Tracy Prinster, Alistair Harrison, Christopher Dick, Dennis J. Horvath, Birong Li, Grace Sievers, Revanth Madamsetty, Jingwen Zhang, Kevin M. Mason, Christina Khoo, Sheryl S. Justice   +10 more
doaj   +1 more source

Terahertz pulse generation by two-color laser fields with circular polarization

New Journal of Physics, 2020
We study the influence of the polarization states of ionizing femtosecond two-color pulses on the emitted terahertz radiation in gases. A local-current model and plane-wave evaluations justify the previously-reported impact on the THz energy yield and
C Tailliez, A Stathopulos, S Skupin, D Buožius, I Babushkin, V Vaičaitis, L Bergé   +6 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

GlcNAc induces GlcNAc catabolic genes and inhibits filamentation via YlRep1-YlNgs1 signaling in the dimorphic yeast Yarrowia lipolytica

mSphere
Many fungal species can utilize N-acetylglucosamine (GlcNAc) as a carbon source. Studies in the pathogenic yeast Candida albicans have revealed that GlcNAc utilization and the induction of GlcNAc catabolic genes depend on the Ndt80 family transcription ...
Zhen-Hua Wang, Meng-Yang Xu, Xiang-Dong Gao   +2 more
doaj   +1 more source

The 5′ Untranslated Region of the EFG1 Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in Candida albicans

mSphere, 2018
Extensive 5′ untranslated regions (UTR) are a hallmark of transcripts determining hyphal morphogenesis in Candida albicans. The major transcripts of the EFG1 gene, which are responsible for cellular morphogenesis and metabolism, contain a 5′ UTR of up to
Prashant R. Desai, Klaus Lengeler, Mario Kapitan, Silas Matthias Janßen, Paula Alepuz, Ilse D. Jacobsen, Joachim F. Ernst   +6 more
doaj   +1 more source

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues. [PDF]

PLoS Genetics, 2016
The capacity to transition between distinct morphological forms is a key virulence trait for diverse fungal pathogens. A poignant example of a leading opportunistic fungal pathogen of humans for which an environmentally responsive developmental program ...
Jinglin L Xie, Nora Grahl, Trevor Sless, Michelle D Leach, Sang Hu Kim, Deborah A Hogan, Nicole Robbins, Leah E Cowen   +7 more
doaj   +1 more source

The Znf2 downstream target Pum1 directs filamentation.

, 2014
(A) The 29 Znf2 downstream targets were placed under the control of the constitutive PGDP1 promoter to construct a Cryptococcus overexpression library.
James J. Cai (266155), Rachana Gyawali (573435), Srijana Upadhyay (573436), Xiuyun Tian (185166), Gang Wang (36685), Xiaorong Lin (22332), Linqi Wang (157367), Dylan Foyle (573437)   +7 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

The role of turbulence in bottom-up nanoparticle synthesis using ultrafast laser filamentation in ethanol

Journal of the Mechanical Behavior of Materials
Ultrafast laser filamentation in liquids based on nonlinear optical phenomenon is a new method for bottom-up nanoparticle synthesis. The process is able to synthesize nanomaterials such as nanodiamonds from the liquid precursor.
Tan Han Yi, Ong Guang Liang, Nee Chen Hon, Tou Teck Yong, Yap Seong Ling, Sanz-Navarro Carlos Federico, Lee Siaw Foon, Yap Seong Shan   +7 more
doaj   +1 more source

Transcriptional Alterations of Virulence-Associated Genes in Extended Spectrum Beta-Lactamase (ESBL)-Producing Uropathogenic Escherichia coli during Morphologic Transitions Induced by Ineffective Antibiotics

Frontiers in Microbiology, 2017
It is known that an ineffective antibiotic treatment can induce morphological shifts in uropathogenic Escherichia coli (UPEC) but the virulence properties during these shifts remain to be studied.
Isak Demirel, Isak Demirel, Ignacio Rangel, Ignacio Rangel, Ulrika Petersson, Katarina Persson, Katarina Persson, Robert Kruse, Robert Kruse   +8 more
doaj   +1 more source