Results 51 to 60 of about 16,146 (298)

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent

mSphere
Candida albicans is one of the most common causes of superficial and invasive fungal diseases in humans. Its ability to cause disease is closely linked to its ability to undergo a morphological transition from budding yeast to filamentous forms (hyphae ...
Rohan S. Wakade, Melanie Wellington, Damian J. Krysan   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Discrete damage traces from filamentation of Gauss-Bessel pulses [PDF]

, 2006
Filamentation of Bessel-Gauss pulses propagating in borosilicate glass is found to produce damage lines extending over hundreds of micrometers and consisting of discrete, equidistant damage spots.
Vanagas, Egidijus, Mizeikis, Vygantas, Gaizauskas, Eugenijus, Jarutis, Vygandas, Juodkazis, Saulius, Misawa, Hiroaki   +5 more
core  

Recent developments in femtosecond filamentation

, 2014
International audienceWe review recent developments in the field of femtosecond laser ...
Houard, Aurélien, Mysyrowicz, André, Liu, Yi   +2 more
core   +1 more source

Dark filament

ACM SIGGRAPH 2007 art gallery, 2007
James Faure Walker exhibited his piece, ‘Dark Filament’ in 'Digital Pioneers', a seminal exhibition at the V&A showing early works by pioneer digital artists from all over the world and put on in parallel with the ‘Decode’ exhibition of current interactive digital art at the V&A.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

TUP1-mediated filamentation in Candida albicans leads to inability to colonize the mouse gut

, 2018
Aim: To investigate the role of Candida albicans TUP1-mediated filamentation in the colonization of the mice gut. Materials & methods: We used molecular genetics to generate a strain where filamentation is regulated by altering the expression of the
Blanca Huertas, Román González, Elvira, Pla Alonso, Jesús, Huertas, Blanca, Daniel Prieto, Elvira Román, Jesús Pla, Prieto, Daniel, Rosalía Díez-Orejas, Díez Orejas, Rosalía María   +9 more
core   +1 more source

Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation

mBio, 2017
Candida albicans remains the main etiologic agent of candidiasis, the most common fungal infection and now the third most frequent infection in U.S. hospitals.
Jesus A. Romo, Christopher G. Pierce, Ashok K. Chaturvedi, Anna L. Lazzell, Stanton F. McHardy, Stephen P. Saville, Jose L. Lopez-Ribot   +6 more
doaj   +1 more source

Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype

Molecular Systems Biology, 2021
The relationship between sequence variation and phenotype is poorly understood. Here, we use metabolomic analysis to elucidate the molecular mechanism underlying the filamentous phenotype of E.
Sanchari Bhattacharyya, Shimon Bershtein, Bharat V Adkar, Jaie Woodard, Eugene I Shakhnovich   +4 more
doaj   +1 more source