Results 91 to 100 of about 5,542 (153)

Evaluation of inactivated Bordetella pertussis as a delivery system for the immunization of mice with Pneumococcal Surface Antigen A.

PLoS ONE, 2020
Pneumococcal Surface Protein A (PspA) has been successfully tested as vaccine candidate against Streptococcus pneumoniae infections. Vaccines able to induce PspA-specific antibodies and Th1 cytokines usually provide protection in mice. We have shown that
Julia T Castro, Giuliana S Oliveira, Melissa A Nishigasako, Anne-Sophie Debrie, Eliane N Miyaji, Alessandra Soares-Schanoski, Milena A Akamatsu, Camille Locht, Paulo L Ho, Nathalie Mielcarek, Maria Leonor S Oliveira   +10 more
doaj   +1 more source

FHA-mediated cell-substrate and cell-cell adhesions are critical for Bordetella pertussis biofilm formation on abiotic surfaces and in the mouse nose and the trachea.

PLoS ONE, 2011
Bordetella spp. form biofilms in the mouse nasopharynx, thereby providing a potential mechanism for establishing chronic infections in humans and animals. Filamentous hemagglutinin (FHA) is a major virulence factor of B. pertussis, the causative agent of
Diego O Serra, Matt S Conover, Laura Arnal, Gina Parise Sloan, María E Rodriguez, Osvaldo M Yantorno, Rajendar Deora   +6 more
doaj   +1 more source

Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites

npj Viruses
The hemagglutinin (HA) glycoprotein of influenza virus binds host cell receptors and mediates viral entry. Here we present cryo-EM structures of fully glycosylated HAs from H5N1 and H5N8 influenza viruses. We find that the H5N1 HA can form filaments that
Ruofan Li, Jingjing Gao, Lin Wang, Miao Gui, Ye Xiang   +4 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Quantitative bead-based multiplex assay for simultaneous determination of IgG concentrations of pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria, tetanus, Haemophilus influenzae b, and hepatitis B in human serum samples. [PDF]

Front Immunol
Rathod V, Katke S, Patil S, Bhandare S, Kadam L, Gautam M, Gumma P, Kumar KM, Hassall L, Asokanathan C, Douglas-Bardsley A, Markey K, Gupta S, Rao H, Parekh S, Pujari P, Sharma H, Shaligram U, Gairola S.   +18 more
europepmc   +1 more source

Mucosal and systemic immune responses elicited by recombinant Lactococcus lactis expressing a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis. [PDF]

Microb Pathog, 2018
Torkashvand A, Bahrami F, Adib M, Ajdary S.   +3 more
europepmc   +1 more source

Virus-like particles displaying the mature C-terminal domain of filamentous hemagglutinin are immunogenic and protective against Bordetella pertussis respiratory infection in mice. [PDF]

Infect Immun
Pyles GM, Huckaby AB, Gutierrez MdlP, Witt WT, Mateu-Borrás M, Dublin SR, Rocuskie-Marker C, Sesti BN, Peasak K, Bitzer GJ, Rader N, Weaver KL, Boehm DT, Fitzgerald N, Chapman J, Ulicny S, Damron FH, Barbier M.   +17 more
europepmc   +1 more source

The seroepidemiology of immunoglobulin G antibodies against pertussis toxin and filamentous hemagglutinin in the east of China during the COVID-19 pandemic. [PDF]

Hum Vaccin Immunother
Sun X, Zhang T, Sun J, Zhou J, Chen Q, Jia C, Xu Y, Wu Y, Wang Z, Wang W.   +9 more
europepmc   +1 more source

Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities. [PDF]

PLoS Pathog
Benegal A, He Y, Ho K, Groff G, Guo Z, Vahey MD.   +5 more
europepmc   +1 more source