Results 11 to 20 of about 6,369 (156)

Pegfilgrastim prophylaxis is associated with a lower risk of hospitalization of cancer patients than filgrastim prophylaxis: a retrospective United States claims analysis of granulocyte colony-stimulating factors (G-CSF)

BMC Cancer, 2013
Background Myelosuppressive chemotherapy can lead to dose-limiting febrile neutropenia. Prophylactic use of recombinant human G-CSF such as daily filgrastim and once-per-cycle pegfilgrastim may reduce the incidence of febrile neutropenia.
Naeim Arash, Henk Henry J, Becker Laura, Chia Victoria, Badre Sejal, Li Xiaoyan, Deeter Robert   +6 more
doaj   +1 more source

Effectiveness of filgrastim and polyethylene glycol-filgrastim in the treatment of postchemotherapy neutropenia in children: Phase I clinical trial

Indian Journal of Medical and Paediatric Oncology, 2019
Background: One of the most common side effects of chemotherapy in cancer patients is neutropenia that can result in hospitalization. The purpose of this study was to evaluate the efficacy and tolerability of polyethylene glycol (PEG)-filgrastim compared
Saeed Yousofian, Ghasem Miri-Aliabad, Azadeh Kiumarsi, Tayeb Ramim   +3 more
doaj   +1 more source

Neupogen (Filgrastim) Induced Acute Hematuria/Proteinuria with 3 Days of Use in a 7-Year-old Boy Diagnosed as Aplastic Anemia

Dr. Sulaiman Al Habib Medical Journal, 2020
Filgrastim, a granulocyte-colony stimulating factor (G-CSF), is used in patients with neutropenia caused by chemotherapy, bone marrow transplant, radiation poisoning, or any unknown etiology.
Sohail Azam, Hassan Eliwan, Fatima Eltayeb Hago, Al Husein Mohammed Chyad Hammoudi   +3 more
doaj   +1 more source

Extension of human GCSF serum half-life by the fusion of albumin binding domain

Scientific Reports, 2022
Granulocyte colony stimulating factor (GCSF) can decrease mortality of patients undergo chemotherapy through increasing neutrophil counts. Many strategies have been developed to improve its blood circulating time.
Fatemeh Yadavar Nikravesh, Samira Shirkhani, Elham Bayat, Yeganeh Talebkhan, Esmat Mirabzadeh, Masoumeh Sabzalinejad, Hooman Aghamirza Moghim Aliabadi, Leila Nematollahi, Yalda Hosseinzadeh Ardakani, Soroush Sardari   +9 more
doaj   +1 more source

Effects of Ocimum tenuiflorum on Induced Testicular Degeneration by Filgrastim in Wistar Rats [PDF]

Archives of Razi Institute, 2021
Since the creation of man on earth, herbal remedies have been used as an invaluable, safe, and available natural source of medicine for the treatment of several dysfunctions in living animals and human beings.
G. S Tuimah Alabedi, H. F AL-Baghdady, M. A Alahmer, G. S Bustani, A. M. B Al-Dhalimy   +4 more
doaj   +1 more source

Mobilization of hematopoietic progenitor cells with granulocyte colony stimulating factors for autologous transplant in hematologic malignancies: a single center experience

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: In 2006 the Hematology Service of Hospital Maciel published its experience with peripheral blood progenitor cell harvesting for autologous stem cell transplantation using Filgen JP (Clausen Filgrastim).
Raul Gabús, Gabriel Borelli, Martín Ferrando, Enrique Bódega, Estela Citrín, Constanza Olivera Jiménez, Ramón Álvarez   +6 more
doaj   +1 more source

Filgrastim Protects the Cerebellar Cortex Against TNF-α/Bax Enhanced Apoptosis After Aluminum Toxicity in Albino Rats. Histological and Immunohistochemical Study [PDF]

The Egyptian Journal of Histology
Introduction: Aluminum (Al) is a strong toxicant affecting the brain neurons. Filgrastim can be a promising protective drug.Aim of the Work: Evaluation of the neuro-alleviating role of Filgrastim on the Aluminum-induced neuronal toxicity in the ...
Heba Bayoumi, Mona Mohamed, Hala Shalan, Ebtssam Beder, Enas Elgendy   +4 more
doaj   +1 more source

Assessment of Granulocyte-Colony Stimulating Factors Use at a community-based teaching hospital and compliance with National Comprehensive Cancer Network guidelines

Journal of Taibah University Medical Sciences, 2020
Objectives: Approximately 60,000 patients are hospitalised annually due to chemotherapy-induced febrile neutropenia (FN) in the United States alone. Febrile neutropenia is primarily managed by antibiotics and granulocyte-colony-stimulating factors (G ...
Abdullah A. Alhifany, PharmD, Matthew W. McAllister, PharmD   +1 more
doaj   +1 more source

Anaphylaxis from filgrastim prophylaxis within the same day of chemotherapy: A case report

Current Problems in Cancer: Case Reports
Introduction: Filgrastim is recommended to be used 24–72 h after the last dose of chemotherapy for the prophylaxis of febrile neutropenia. However, several studies demonstrate the efficacy and safety of the use of filgrastim within the same day of the ...
Suluck Soontaros, Supaporn Wongduang, Nattawut Leelakanok   +2 more
doaj   +1 more source

G-CSF filgrastim biosimilar-Sandoz reduces the incidence of febrile neutropenia in patients receiving chemotherapy regimens with rest periods not exceeding 14 days: A French, multicenter, prospective, non-interventional study

Cancer Treatment and Research Communications, 2023
Purpose: The objective of this study was to describe filgrastim biosimilar-Sandoz modalities of use in patients receiving cytotoxic chemotherapy regimens with a rest period of ≤14 days and to investigate the incidence of febrile neutropenia (FN) in ...
Jean-Marc Phelip, Pierre-Jean Souquet, Maya Hacini, Mohamad Chehimi, Vincent Bourgeois, Ryma Bennoune, Olivier Tredan   +6 more
doaj   +1 more source