Results 41 to 50 of about 6,369 (156)

Impact of Preanalytical Sample Preparation on the Recovery Rate of Cryopreserved Allogeneic Hematopoietic Stem Cells

European Journal of Haematology, Volume 116, Issue 5, Page 604-614, May 2026.
ABSTRACT Introduction Cryopreservation of peripheral‐blood‐derived hematopoietic stem and progenitor cells (PBSCs) has been used for decades, primarily for autologous transplantation. Now, in the era of new cellular therapies, the cryopreservation of allogeneic PBSCs may also become relevant.
Philipp Blüm, Christina Glas, Karen Bieback, Sabine Kayser, Harald Klüter, Patrick Wuchter   +5 more
wiley   +1 more source

Biopharmaceuticals for Cancer Treatment: An Update

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath, Yousuf Alam, Afsana Mustak Mim, Maksuda Akter, Mohammad Abbas Gani, Khondaker Muhammad Khairul Alam, Md. Nur Alam   +6 more
wiley   +1 more source

Validation of an in vitro biological method for filgrastim potency assessment

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Filgrastim is a human granulocyte colony-stimulating factor produced using recombinant DNA technology. Since filgrastim quality control necessitates a validated method, establishing the entire method validation parameters is of high ...
L. A. Gaiderova, M. L. Baykova, O. V. Golovinskaya, S. L. Lysikova, V. V. Fomenko, N. A. Alpatova   +5 more
doaj   +1 more source

Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy: systematic review and meta-analysis

BMC Cancer, 2011
Background Febrile neutropenia (FN) occurs following myelosuppressive chemotherapy and is associated with morbidity, mortality, costs, and chemotherapy reductions and delays. Granulocyte colony-stimulating factors (G-CSFs) stimulate neutrophil production
Stevenson Matt D, Whyte Sophie, Madan Jason, Cooper Katy L, Akehurst Ron L   +4 more
doaj   +1 more source

Linkage Between miR‐218‐2 (rs11134527) Genetic Polymorphism and Breast Cancer Risk: A Case‐Control Study in the Bangladeshi Women

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims The growth and spread of breast carcinoma are influenced by genetic factors. Diverse forms of cancer have been reported to display multiple subtypes of the microRNA gene. Therefore, the current study aimed to explore the connection between the miR‐218‐2 (rs11134527) and breast cancer risk.
A. M. Shamim, Aiman Hossan, Md. Shafiul Hossen, Md Abdul Barek, Mohammad A. Rashid, Mohammad Safiqul Islam   +5 more
wiley   +1 more source

Monocentric Analysis of the Effectiveness and Financial Consequences of the Use of Lenograstim versus Filgrastim for Mobilization of Peripheral Blood Progenitor Cells in Patients with Lymphoma and Myeloma Receiving Chemotherapy and Autologous Stem Cell Transplantation

Journal of Blood Medicine, 2020
Umberto Restelli,1,2 Davide Croce,1,2 Erminio Bonizzoni,3 Mario Marzanatti,3 Angelo Andreini,4 Marco Sorio,4 Cristina Tecchio,4 Erika Barison,4 Fabio Benedetti4 1School of Public Health, Faculty of Health Sciences, University of Witwatersrand ...
Restelli U, Croce D, Bonizzoni E, Marzanatti M, Andreini A, Sorio M, Tecchio C, Barison E, Benedetti F   +8 more
doaj  

Predictive Role of Serum Inflammatory Markers in Metastatic Luminal A/B Breast Cancers Receiving CDK‐4/6 Inhibitors Therapy

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background We conducted this study to evaluate the impact of serum inflammatory markers and histopathological features on prognosis in metastatic hormone receptor positive breast cancer patients treated with first line CDK4/6i (cyclin‐dependent kinase inhibitors).
Nilufer Bulut, Tanju Kapagan, Aykut Ozmen, Gokmen Umut Erdem   +3 more
wiley   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience

Turkish Journal of Internal Medicine, 2020
Introduction. Granulocyte colony-stimulating factor (G-CSF) therapy is commonly used in kidney and liver transplant recipients with severe neutropenia.
Emel Isiktas Sayilar, Alparslan Ersoy, Sedat Çelikçi, Vildan Ozkocaman, Fahir Özkalemkaş, Rıdvan Ali, Yavuz Ayar   +6 more
doaj   +1 more source