Results 61 to 70 of about 12,775 (197)

Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy: systematic review and meta-analysis

BMC Cancer, 2011
Background Febrile neutropenia (FN) occurs following myelosuppressive chemotherapy and is associated with morbidity, mortality, costs, and chemotherapy reductions and delays. Granulocyte colony-stimulating factors (G-CSFs) stimulate neutrophil production
Stevenson Matt D, Whyte Sophie, Madan Jason, Cooper Katy L, Akehurst Ron L   +4 more
doaj   +1 more source

Pegfilgrastim reduces the length of hospitalization and the time to engraftment in multiple myeloma patients treated with melphalan 200 and auto-SCT compared with filgrastim [PDF]

, 2018
To reduce the duration of neutropenia after conditioning chemotherapy and autologous peripheral blood stem cell transplantation (APBSCT), granulocyte-colony stimulating factors (G-CSF) are commonly administered. We retrospectively evaluated the impact of
Blickenstorfer, Marcel, Buset, Elefteri, Haile, Sarah, Honegger, Hanspeter, Knuth, Alexander, Mischo, Axel, Petrausch, Ulf, Renner, Christoph, Samaras, Panagiotis, Schanz, Urs, Siciliano, Raffaele, Stahel, Rolf, Stenner-Liewen, Frank, Stussi, Georg   +13 more
core  

Production of the High Value Pharmaceutical Target, Human Granulocyte‐Colony Stimulating Factor, in Nicotiana benthamiana Is Improved by Co‐Expression of the Transcriptional Regulator of the Unfolded Protein Response, bZIP60

Plant Biotechnology Journal, EarlyView.
Nazgul Wagner, Konstantin Musiychuk, Stephen Tottey, Jukka Kervinen, Hong Bi, Stephen J. Streatfield, Rainer Fischer, Vidadi Yusibov   +7 more
wiley   +1 more source

A Clinically Relevant Drug Interaction Between Busulfan and Rifampin in the Setting of Hematopoietic Stem Cell Transplant Conditioning

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Busulfan is an alkylating agent used in combination with other chemotherapeutic agents and has become a common component of conditioning regimens prior to hematopoietic stem cell transplantation. Busulfan has a very narrow therapeutic index corresponding to the area under the plasma concentration–time curve, with supra‐therapeutic busulfan ...
Colleen Drangines, Janet Laquet, Ranju Kunwor   +2 more
wiley   +1 more source

Validation of an in vitro biological method for filgrastim potency assessment

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Filgrastim is a human granulocyte colony-stimulating factor produced using recombinant DNA technology. Since filgrastim quality control necessitates a validated method, establishing the entire method validation parameters is of high ...
L. A. Gaiderova, M. L. Baykova, O. V. Golovinskaya, S. L. Lysikova, V. V. Fomenko, N. A. Alpatova   +5 more
doaj   +1 more source

Implantation of a poly-L-lactide GCSF-functionalized scaffold in a model of chronic myocardial infarction [PDF]

, 2017
A previously developed poly-l-lactide scaffold releasing granulocyte colony-stimulating factor (PLLA/GCSF) was tested in a rabbit chronic model of myocardial infarction (MI) as a ventricular patch.
Chello, Massimo, Crescenzi, Anna, De Marco, Federico, Gambardella, Ivancarmine, Nappi, Francesco, Nenna, Antonio, Rainer, Alberto, Sedati, Pietro, Spadaccio, Cristiano, Taffon, Chiara, Trombetta, Marcella   +10 more
core   +1 more source

Pediatric autologous peripheral blood stem cell collection without heparin using a highly concentrated sodium citrate anticoagulant: A retrospective comparison with standard ACD‐A

Transfusion, Volume 66, Issue 4, Page 677-688, April 2026.
Abstract Background Heparin combined with sodium citrate has been used in leukocytapheresis for pediatric patients. Since 2022, we have performed leukocytapheresis using a highly concentrated sodium citrate solution (HSC, 5.32%) instead of acid citrate dextrose solution A (ACD‐A).
Keiko Fujii, Wataru Kitamura, Kana Washio, Kazuhiro Ikeuchi, Joji Shimono, Hiroyuki Murakami, Fumio Otsuka, Yoshinobu Maeda, Nobuharu Fujii   +8 more
wiley   +1 more source

Monocentric Analysis of the Effectiveness and Financial Consequences of the Use of Lenograstim versus Filgrastim for Mobilization of Peripheral Blood Progenitor Cells in Patients with Lymphoma and Myeloma Receiving Chemotherapy and Autologous Stem Cell Transplantation

Journal of Blood Medicine, 2020
Umberto Restelli,1,2 Davide Croce,1,2 Erminio Bonizzoni,3 Mario Marzanatti,3 Angelo Andreini,4 Marco Sorio,4 Cristina Tecchio,4 Erika Barison,4 Fabio Benedetti4 1School of Public Health, Faculty of Health Sciences, University of Witwatersrand ...
Restelli U, Croce D, Bonizzoni E, Marzanatti M, Andreini A, Sorio M, Tecchio C, Barison E, Benedetti F   +8 more
doaj  

Systemic Therapy in Endometrial Cancer: Recent Advances. [PDF]

, 2013
Endometrial cancer is a chemosensitive disease. Studies have established a clear benefit of chemotherapy in advanced stages and trials are ongoing to define its role in early stages as well.
Bhise, R, Guru Prasad B, B, Kundargi, R, Lakshmaia, KC, Purohit, S, Shetty, R   +5 more
core   +1 more source

Pegfilgrastim compared with Filgrastim after autologous hematopoietic peripheral blood stem cell transplantation. [PDF]

, 2006
peer reviewedIn order to assess the effect of Pegfilgrastim on the duration of neutropenia and clinical outcome of patients after autologous peripheral blood stem cell (PBSC) transplantation, we compared 20 consecutive patients with lymphoma or multiple ...
Beguin, Yves, Fillet, Georges, Frere, Pascale, Ngirabacu, Marie-Christine, Vanstraelen, Gaetan, Willems, Evelyne   +5 more
core   +1 more source