Results 71 to 80 of about 12,775 (197)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 442-452, March 2026.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Consult Series #76: Cancer in pregnancy

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Approximately one in 1000 pregnancies is complicated by the diagnosis of cancer each year, and the incidence of cancer among reproductive‐age individuals is increasing. Management of a pregnant person with cancer can be complex and warrants a multidisciplinary approach to care.
Society for Maternal‐Fetal Medicine (SMFM), Moti Gulersen, Clarissa Bonanno, Justin S. Brandt, Stephanie Pierce, Elyce H. Cardonick, SMFM Publications Committee   +6 more
wiley   +1 more source

Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience

Turkish Journal of Internal Medicine, 2020
Introduction. Granulocyte colony-stimulating factor (G-CSF) therapy is commonly used in kidney and liver transplant recipients with severe neutropenia.
Emel Isiktas Sayilar, Alparslan Ersoy, Sedat Çelikçi, Vildan Ozkocaman, Fahir Özkalemkaş, Rıdvan Ali, Yavuz Ayar   +6 more
doaj   +1 more source

Granulocyte colony-stimulating factors for prevention of febrile neutropenia following chemotherapy: systematic review and meta-analysis [PDF]

Background: Febrile neutropenia (FN) occurs following myelosuppressive chemotherapy and is associated with morbidity, mortality, costs, and chemotherapy reductions and delays.
Akehurst, R., Cooper, K.L., Madan, J., Stevenson, M.D., Whyte, S.   +4 more
core  

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, Volume 15, Issue 7, 16 February 2026.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis: systematic review and mixed method treatment comparison [PDF]

Background This study assesses the efficacy of three granulocyte colony-stimulating factors (G-CSFs; pegfilgrastim, filgrastim and lenograstim) in preventing febrile neutropenia (FN). Methods A systematic review was undertaken.
Akehurst, R., Cooper, K.L., Madan, J., Stevenson, M.D., Whyte, S.   +4 more
core  

Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery [PDF]

, 2009
Background: Grade IV chemotherapy toxicity is defined as absolute neutrophil count <500/μL. The nadir is considered as the lowest neutrophil number following chemotherapy, and generally is not expected before the 7th day from the start of chemotherapy.
Abbasciano V, Albertini F, Barile C, Bononi A, CAMPIONI, Diana, Crepaldi G, Ferrari L, Ferrazzi E, Gilli G, Gusella M, Lanza F, Menon D, Pasini F., Russo A, Stievano L, Toso S   +15 more
core   +1 more source

Enhancing Severe Neutropenia Prediction: PKPD‐Informed Labeling for Machine Learning Models Trained on Real‐World Data

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 427-436, February 2026.
Accurately labeling outcomes in real‐world data for machine learning is challenging due to data sparsity and imbalances. This study developed and evaluated a pharmacokinetic–pharmacodynamic (PKPD)‐informed labeling strategy to enhance the risk prediction of docetaxel‐induced neutropenia.
Conor J O’Hanlon, Jonas Denck, Elif Ozkirimli, Stefanie Bendels, Candice Jamois, Clarisse Chavanne, Dirk Fey, Kimmo Porkka, Oscar Brück, Ken Wang   +9 more
wiley   +1 more source

Recombinant human granulocyte colony stimulating factor versus bone marrow mononuclear cells in treatment of pulmonary emphysema model

Egyptian Journal of Chest Disease and Tuberculosis, 2017
Background: Stem cells therapy is a new therapeutic approach for pulmonary emphysema. Granulocyte colony-stimulating factor (G-CSF) is effective in tissue regeneration through mobilization of stem cells to different organs.
Mohammad K. El-badrawy, Nesrein M. Shalabi, Mie A. Mohamed, Amany Ragab, Heba Wagih Abdelwahab, Nahla Anber, Mohamed A. Sobh, Yomna Khater, Aziza A. Abdel Hamid   +8 more
doaj   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu, Zhi‐Ping Jin, Shu‐Qiang Weng, Ji‐Min Zhu, Ling Dong   +4 more
wiley   +1 more source