Results 21 to 30 of about 35,622 (198)
The small GTPase Rif is dispensable for platelet filopodia generation in mice. [PDF]
PLoS ONE, 2013 Formation of filopodia and other shape change events are vital for platelet hemostatic function. The mechanisms regulating filopodia formation by platelets are incompletely understood however.
Robert Goggs +3 more
doaj +1 more source
Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]
, 2012 Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Reddy, M +10 more
core +1 more source
Scientific Reports, 2017 Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we report the mechanism of myosin X (encoded by Myo10)-induced multi-cycle filopodia extension.
Kangmin He +4 more
doaj +1 more source
Cells, 2021 The cellular mechanisms of basement membrane (BM) invasion remain poorly understood. We investigated the invasion-promoting mechanisms of actin cytoskeleton reorganization in BM-covered MCF10A breast acini.
Julian Eschenbruch +6 more
doaj +1 more source
Tissue guidance without filopodia [PDF]
, 2014 Filopodia are highly dynamic, rod-like protrusions that are found in abundance at the leading edge of migrating cells such as endothelial tip cells and at axonal growth cones of developing neurons.
Phng, L.K., Wacker, A., Gerhardt, H.
core +1 more source
Cells, 2022 Many nervous proteins are expressed in cancer cells. In this report, we asked whether the synaptic protein neuroligin 1 (NLGN1) was expressed by prostatic and pancreatic carcinomas; in addition, given the tendency of these tumors to interact with nerves,
Laura Bizzozero +10 more
doaj +1 more source
Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin [PDF]
, 2001 Cdc42Hs is involved in cytoskeletal reorganization and is required for neurite outgrowth in N1E-115 cells. To investigate the molecular mechanism by which Cdc42Hs regulates these processes, a search for novel Cdc42Hs protein partners was undertaken by ...
Sheila Govind +9 more
core +1 more source
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). [PDF]
PLoS Biology, 2009 The regulation of filopodia plays a crucial role during neuronal development and synaptogenesis. Axonal filopodia, which are known to originate presynaptic specializations, are regulated in response to neurotrophic factors.
Elisabetta Menna +13 more
doaj +1 more source
The making of filopodia. [PDF]
, 2006 Filopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. They are found on a variety of cell types and have been ascribed sensory or exploratory functions.
Rottner, Klemens, Faix, Jan
core +1 more source
Frontiers in Medicine, 2023 IntroductionIn chronic lymphocytic leukemia (CLL), the tumor cells receive survival support from stromal cells through direct cell contact, soluble factors and extracellular vesicles (EVs).
Thaís Dolzany de Oliveira +24 more
doaj +1 more source