Results 31 to 40 of about 35,622 (198)

Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons

eLife, 2014
In the vertebrate central nervous system, exploratory filopodia transiently form on dendritic branches to sample the neuronal environment and initiate new trans-neuronal contacts.
Milos Galic, Feng-Chiao Tsai, Sean R Collins, Maja Matis, Samuel Bandara, Tobias Meyer   +5 more
doaj   +1 more source

Learning the language of pathogens

eLife, 2023
Parasites can use extracellular vesicles and cellular projections called cytonemes to communicate with one another.
Izadora Volpato Rossi, Marcel Ivan Ramirez   +1 more
doaj   +1 more source

Myosin-X recruits lamellipodin to filopodia tips

, 2022
Myosin-X (MYO10), a molecular motor localizing to filopodia, is thought to transport various cargo to filopodia tips, modulating filopodia function. Yet, only a few MYO10 cargoes have been described.
Grönloh, Max LB, Popović, Ana, Ghimire, Sujan, Ball, Neil, Miihkinen, Mitro, Ivaska, Johanna, Goult, Benjamin, Jacquemet, Guillaume, Saup, Rafael   +8 more
core   +1 more source

Filopodia powered by class x myosin promote fusion of mammalian myoblasts

eLife, 2021
Skeletal muscle fibers are multinucleated cellular giants formed by the fusion of mononuclear myoblasts. Several molecules involved in myoblast fusion have been discovered, and finger-like projections coincident with myoblast fusion have also been ...
David W Hammers, Cora C Hart, Michael K Matheny, Ernest G Heimsath, Young il Lee, John A Hammer III, Richard E Cheney, H Lee Sweeney   +7 more
doaj   +1 more source

An algorithm for quantifying filopodia of multiple cells with weak fluorescence signal

Journal of Innovative Optical Health Sciences
Filopodia function as cellular sensors, detecting the microenvironment and directing cell migration. They play a crucial role in cancer metastasis. Quantifying the filopodia characteristics of cancer cells is a prerequisite for studying the complex role ...
Muyang Hao, Hongcong Zheng, Xiaoyan Wang, Qing Ye, Renqun Liu, Yimei Huang   +5 more
doaj   +1 more source

The Arp2/3 complex, UNC-115/abLIM, and UNC-34/Enabled regulate axon guidance and growth cone filopodia formation in Caenorhabditis elegans

Neural Development, 2009
Background While many molecules involved in axon guidance have been identified, the cellular and molecular mechanisms by which these molecules regulate growth cone morphology during axon outgrowth remain to be elucidated.
Lundquist Erik A, Dyer Jamie O, Norris Adam D   +2 more
doaj   +1 more source

The Process of Filopodia Induction during HPV Infection

Viruses, 2022
Human Papillomavirus 16 (HPV16) infects mucosal and epithelial cells and has been identified as a high-risk HPV type that is an etiologic agent of human cancers.
Alyssa Biondo, Patricio I. Meneses
doaj   +1 more source

3D‐Printed Titanium Gyroid Scaffold Structure Integrated With Tough Hybrid Materials for Cartilage Replacement

Advanced Engineering Materials, EarlyView.
This study proposes a potential device design for joint cartilage replacement. Silica‐polytetrahydrofuran (SiO2‐PolyTHF) hybrids with customizable mechanical properties were developed to mimic the characteristics of a natural meniscus. These were synthesized through a two‐pot sol–gel hybrid process.
Yu‐Chien Lin, Gloria R. Young, Francesca Tallia, Reece N. Oosterbeek, Shaaz Ghouse, Edward Spiers, Nupur Kohli, Tom Briggs, Marc Masen, Siwei Li, Ren‐Jei Chung, Jonathan R. T. Jeffers, Julian R. Jones   +12 more
wiley   +1 more source

Dynamics of filopodia tip complexes [PDF]

, 2020
The shape of many eukaryotic cells depends on the actin cytoskeleton, and changes in actin assembly dynamics underlie many changes in cell shape. Ena/VASP-family actin polymerases, for example, modulate cell shape by locally accelerating actin filament ...
Cheng, Karen
core   +1 more source

Filopodia in cell adhesion, 3D migration and cancer cell invasion [PDF]

, 2015
This review discusses recent advances in our understanding of the role filopodia and filopodia-like structures in cell adhesion and three dimensional (3D) cell migration both in vitro and in vivo.
Hamidi, Hellyeh, Ivaska, Johanna, Jacquemet, Guillaume   +2 more
core   +1 more source