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Filoviridae evolution and Ebola virus outbreaks throughout human history
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Impacts of the Filoviridae family
Current Opinion in Pharmacology, 2021Over 40 filovirus disease outbreaks have been reported since the discovery of the first member of the Filoviridae family, and most of the outbreaks have occurred in Africa. In addition to deaths (primary impacts), there have also been health, social, economic, and political effects (secondary impacts) due to the outbreaks.
Sylvester Languon, Osbourne Quaye
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Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Maria Rosaria Capobianchi +2 more
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Characteristics of Filoviridae: Marburg and Ebola Viruses
Die Naturwissenschaften, 1999Filoviruses are enveloped, nonsegmented negative-stranded RNA viruses. The two species, Marburg and Ebola virus, are serologically, biochemically, and genetically distinct. Marburg virus was first isolated during an outbreak in Europe in 1967, and Ebola virus emerged in 1976 as the causative agent of two simultaneous outbreaks in southern Sudan and ...
Alexander Bukreyev
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Molecular Evolution of Viruses of the Family Filoviridae Based on 97 Whole-Genome Sequences [PDF]
ABSTRACT Viruses in the Ebolavirus and Marburgvirus genera (family Filoviridae ) have been associated with large outbreaks of hemorrhagic fever in human and nonhuman primates.
Jonathan S Towner +2 more
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